7CNL
| Crystal structure of TEAD3 in complex with VT105 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, N-[(1S)-1-pyridin-2-ylethyl]-8-[4-(trifluoromethyl)phenyl]quinoline-3-carboxamide, ... | Authors: | Tang, T.T, Konradi, A.W. | Deposit date: | 2020-08-01 | Release date: | 2021-04-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2 -deficient Mesothelioma. Mol.Cancer Ther., 20, 2021
|
|
8PQO
| PITP in complex with the inhibitor VT01545 | Descriptor: | (2~{R})-2-azanyl-3-[(2~{S},3~{R})-2-methyl-5-oxidanylidene-pyrrolidin-3-yl]sulfanyl-propanal, (2~{R})-3-methyl-2-(methylamino)butanoic acid, (2~{R})-4-methyl-2-(methylamino)pentanamide, ... | Authors: | Boura, E, Eisenreichova, A. | Deposit date: | 2023-07-11 | Release date: | 2024-05-08 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Non-vesicular phosphatidylinositol transfer plays critical roles in defining organelle lipid composition. Embo J., 43, 2024
|
|