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8CAV
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BU of 8cav by Molmil
Discovery of the lanthipeptide Curvocidin and structural insights into its trifunctional synthetase CuvL
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CuvA, MAGNESIUM ION, ...
Authors:Sigurdsson, A, Martins, B.M, Duettmann, S.A, Jasyk, M, Dimos-Roehl, B, Schoepf, F, Gemannter, M, Knittel, C.H, Schnegotyzki, R, Schmid, B, Kosol, S, Gonzalez-Viegas, M, Seidel, M, Huegelland, M, Leimkuehler, S, Dobbek, H, Mainz, A, Suessmuth, R.
Deposit date:2023-01-24
Release date:2023-06-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL.
Angew.Chem.Int.Ed.Engl., 62, 2023
8CAR
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BU of 8car by Molmil
Discovery of the lanthipeptide Curvocidin and structural insights into its trifunctional synthetase CuvL
Descriptor: NITRATE ION, PHOSPHATE ION, Serine/threonine protein kinase
Authors:Martins, B.M, Sigurdsson, A, Duettmann, A.A, Jasyk, M, Dimos-Roehl, B, Schoepf, F, Gemander, M, Knittel, C.H, Schegotzki, R, Schmid, B, Kosol, S, Pommerening, L, Gonzalez-Viegas, M, Seidel, M, Huegelland, M, Leimkuehler, S, Dobbek, H, Mainz, A, Suessmuth, R.
Deposit date:2023-01-24
Release date:2023-06-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL.
Angew.Chem.Int.Ed.Engl., 62, 2023
6ET8
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BU of 6et8 by Molmil
Crystal structure of AlbA in complex with albicidin
Descriptor: Albicidin resistance protein, SULFATE ION, albicidin
Authors:Driller, R, Rostock, L, Alings, C, Graetz, S, Suessmuth, R, Mainz, A, Wahl, M.C, Loll, B.
Deposit date:2017-10-25
Release date:2018-08-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular insights into antibiotic resistance - how a binding protein traps albicidin.
Nat Commun, 9, 2018
7B3A
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BU of 7b3a by Molmil
Crystal structure of PamZ
Descriptor: ACETATE ION, ACETYL COENZYME *A, CHLORIDE ION, ...
Authors:Loll, B, Dang, T, Mainz, A, Suessmuth, R, Wahl, M.C.
Deposit date:2020-11-30
Release date:2021-11-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Molecular basis of antibiotic self-resistance in a bee larvae pathogen.
Nat Commun, 13, 2022
7R3W
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BU of 7r3w by Molmil
Crystal structure of the albicidin resistance protein STM3175 from Salmonella typhimurium
Descriptor: Putative bacterial regulatory helix-turn-helix protein
Authors:Dimos, N, Kosol, S, Suessmuth, R, Loll, B.
Deposit date:2022-02-08
Release date:2022-09-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Gene amplifications cause high-level resistance against albicidin in gram-negative bacteria.
Plos Biol., 21, 2023
7Z9C
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BU of 7z9c by Molmil
E.coli gyrase holocomplex with 217 bp DNA and albicidin
Descriptor: DNA (5'-D(*AP*AP*TP*CP*AP*CP*CP*CP*GP*CP*AP*CP*AP*GP*AP*TP*TP*T)-3'), DNA (5'-D(*GP*AP*TP*TP*TP*TP*AP*TP*GP*CP*CP*TP*GP*AP*TP*TP*CP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*CP*TP*GP*TP*GP*CP*GP*GP*GP*T)-3'), ...
Authors:Ghilarov, D, Heddle, J.G.H, Suessmuth, R.
Deposit date:2022-03-21
Release date:2023-02-15
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Molecular mechanism of topoisomerase poisoning by the peptide antibiotic albicidin.
Nat Catal, 6, 2023

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数据于2024-10-30公开中

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