7KMA
 
 | | Crystal structure of eif2Balpha with a ligand. | | Descriptor: | 6-O-phosphono-alpha-D-mannopyranose, ACETATE ION, Translation initiation factor eIF-2B subunit alpha | | Authors: | Nocek, B, Hao, Q, Remarcik, C, Stoll, V, Wong, Y, Sidrauski, C. | | Deposit date: | 2020-11-02 | | Release date: | 2021-07-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Sugar phosphate activation of the stress sensor eIF2B.
Nat Commun, 12, 2021
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7KMF
 | | Sugar phosphate activation of the stress sensor eIF2B | | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | | Authors: | Nocek, B, Hao, Q, Wong, Y, Stoll, V, Sidrauski, C. | | Deposit date: | 2020-11-02 | | Release date: | 2021-07-14 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | Sugar phosphate activation of the stress sensor eIF2B.
Nat Commun, 12, 2021
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8QZZ
 | | Crystal structure of human eIF2 alpha-gamma complexed with PPP1R15A_420-452 | | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Yan, Y, Ron, D. | | Deposit date: | 2023-10-30 | | Release date: | 2024-03-20 | | Last modified: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Substrate recruitment via eIF2 gamma enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response.
Proc.Natl.Acad.Sci.USA, 121, 2024
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