7F3U
| Cryo-EM structure of human TMEM120A in the CoASH-free state | Descriptor: | Transmembrane protein 120A | Authors: | Rong, Y, Gao, Y.W, Song, D.F, Zhao, Y, Liu, Z.F. | Deposit date: | 2021-06-17 | Release date: | 2021-06-30 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells. Elife, 10, 2021
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7F3T
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4WY4
| Crystal structure of autophagic SNARE complex | Descriptor: | Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8 | Authors: | Zhao, M, Brunger, A.T. | Deposit date: | 2014-11-15 | Release date: | 2015-02-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes. Nature, 520, 2015
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5U4M
| RTA-V1C7-G29R-no_salt | Descriptor: | CHLORIDE ION, Ricin, V1C7 VHH antibody | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2016-12-05 | Release date: | 2017-12-13 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies. Proteins, 85, 2017
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5U4L
| RTA-V1C7_G29R-high-salt | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2016-12-05 | Release date: | 2017-12-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies. Proteins, 85, 2017
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6CWK
| Anti-RTA VHH antibody | Descriptor: | 1,2-ETHANEDIOL, Anti-Ricin antibody, CHLORIDE ION, ... | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2018-03-30 | Release date: | 2019-01-16 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (1.256 Å) | Cite: | Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity. Protein Eng. Des. Sel., 31, 2018
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6CWG
| Ricin catalytic subunit bound go A9 VHH antibody | Descriptor: | CHLORIDE ION, Ricin, VHH antibody | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2018-03-30 | Release date: | 2019-01-16 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity. Protein Eng. Des. Sel., 31, 2018
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5BOZ
| Ricin A chain bound to camelid nanobody (VHH9)(E1) | Descriptor: | CHLORIDE ION, Ricin, SULFATE ION, ... | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2015-05-27 | Release date: | 2016-12-07 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
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5E1H
| Ricin toxin in complex with neutralizing single chain monoclonal antibodies (VHHs) | Descriptor: | CHLORIDE ION, F8(JOB10) VHH antibody, Ricin | Authors: | Rudolph, M.J, Vance, D, Shoemaker, C, Mantis, N. | Deposit date: | 2015-09-29 | Release date: | 2016-08-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.032 Å) | Cite: | Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit. Proteins, 84, 2016
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4Z9K
| Ricin A chain bound to camelid nanobody (VHH2)(F5) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ... | Authors: | Rudolph, M.J. | Deposit date: | 2015-04-10 | Release date: | 2016-07-20 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit. Proteins, 84, 2016
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7DV4
| Crystal structure of anti-CTLA-4 VH domain in complex with human CTLA-4 | Descriptor: | 1,2-ETHANEDIOL, 4003-1(VH), Cytotoxic T-lymphocyte protein 4 | Authors: | Li, H, Gan, X, He, Y. | Deposit date: | 2021-01-12 | Release date: | 2022-01-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | An anti-CTLA-4 heavy chain-only antibody with enhanced T reg depletion shows excellent preclinical efficacy and safety profile. Proc.Natl.Acad.Sci.USA, 119, 2022
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4RE1
| Crystal structure of human TEAD1 and disulfide-engineered YAP | Descriptor: | CHLORIDE ION, Transcriptional enhancer factor TEF-1, Yorkie homolog | Authors: | Xu, Z, Zhou, Z. | Deposit date: | 2014-09-21 | Release date: | 2014-11-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides. Faseb J., 29, 2015
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5J56
| RTA-V1C7 | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | Authors: | Rudolph, M.J. | Deposit date: | 2016-04-01 | Release date: | 2016-12-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
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5J57
| V5E1-RTA complex | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ... | Authors: | Rudolph, M.J. | Deposit date: | 2016-04-01 | Release date: | 2016-12-07 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
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