1TV6
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![BU of 1tv6 by Molmil](/molmil-images/mine/1tv6) | HIV-1 Reverse Transcriptase Complexed with CP-94,707 | Descriptor: | 3-[4-(2-METHYL-IMIDAZO[4,5-C]PYRIDIN-1-YL)BENZYL]-3H-BENZOTHIAZOL-2-ONE, reverse transcriptase p51 subunit, reverse transcriptase p66 subunit | Authors: | Pata, J.D, Stirtan, W.G, Goldstein, S.W, Steitz, T.A. | Deposit date: | 2004-06-28 | Release date: | 2004-07-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant RTs resistant to other non-nucleoside inhibitors Proc.Natl.Acad.Sci.USA, 101, 2004
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3BQ2
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![BU of 3bq2 by Molmil](/molmil-images/mine/3bq2) | Post-insertion binary complex of Dbh DNA polymerase | Descriptor: | CALCIUM ION, DNA (5'-D(*DGP*DAP*DAP*DGP*DCP*DCP*DGP*DGP*DCP*DGP*DG)-3'), DNA (5'-D(*DTP*DTP*DCP*DCP*DGP*DCP*DCP*DCP*DGP*DGP*DCP*DTP*DTP*DCP*DC)-3'), ... | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2007-12-19 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into the generation of single-base deletions by the Y family DNA polymerase dbh. Mol.Cell, 29, 2008
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3BQ1
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![BU of 3bq1 by Molmil](/molmil-images/mine/3bq1) | Insertion ternary complex of Dbh DNA polymerase | Descriptor: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*DGP*DAP*DAP*DGP*DCP*DCP*DGP*DGP*DCP*DG)-3'), ... | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2007-12-19 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into the generation of single-base deletions by the Y family DNA polymerase dbh. Mol.Cell, 29, 2008
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3BQ0
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![BU of 3bq0 by Molmil](/molmil-images/mine/3bq0) | Pre-insertion binary complex of Dbh DNA polymerase | Descriptor: | CALCIUM ION, DNA (5'-D(*DGP*DAP*DAP*DGP*DCP*DCP*DGP*DGP*DCP*DG)-3'), DNA (5'-D(*DT*DTP*DCP*DCP*DGP*DCP*DCP*DCP*DGP*DGP*DCP*DTP*DTP*DCP*DC)-3'), ... | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2007-12-19 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the generation of single-base deletions by the Y family DNA polymerase dbh. Mol.Cell, 29, 2008
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3QZ7
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![BU of 3qz7 by Molmil](/molmil-images/mine/3qz7) | T-3 ternary complex of Dpo4 | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*GP*GP*G)-3', 5'-D(*TP*TP*AP*CP*GP*CP*CP*TP*CP*GP*AP*TP*CP*AP*GP*TP*GP*CP*C)-3', ... | Authors: | Pata, J.D, Wu, Y, Wilson, R.C. | Deposit date: | 2011-03-04 | Release date: | 2011-04-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | The y-family DNA polymerase dpo4 uses a template slippage mechanism to create single-base deletions. J.Bacteriol., 193, 2011
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3QZ8
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![BU of 3qz8 by Molmil](/molmil-images/mine/3qz8) | TT-4 ternary complex of Dpo4 | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*AP*GP*G)-3', 5'-D(*TP*TP*AP*CP*GP*CP*CP*TP*TP*GP*AP*TP*CP*AP*GP*TP*GP*CP*C)-3', ... | Authors: | Pata, J.D, Wu, Y, Wilson, R.C. | Deposit date: | 2011-03-04 | Release date: | 2011-04-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | The y-family DNA polymerase dpo4 uses a template slippage mechanism to create single-base deletions. J.Bacteriol., 193, 2011
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4HYK
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![BU of 4hyk by Molmil](/molmil-images/mine/4hyk) | Dbh Ternary Complex (substrates partially disordered) | Descriptor: | DNA (5'-D(*GP*GP*GP*AP*AP*GP*CP*CP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*GP*CP*CP*CP*CP*GP*GP*CP*TP*TP*CP*CP*C)-3'), DNA polymerase IV | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2012-11-13 | Release date: | 2013-01-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure, 21, 2013
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1IM4
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![BU of 1im4 by Molmil](/molmil-images/mine/1im4) | |
4F4X
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![BU of 4f4x by Molmil](/molmil-images/mine/4f4x) | Y-family DNA polymerase chimera Dbh-Dpo4-Dpo4 #2 | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*GP*GP*GP*C)-3'), ... | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2012-05-11 | Release date: | 2013-01-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.049 Å) | Cite: | Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure, 21, 2013
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4F4W
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![BU of 4f4w by Molmil](/molmil-images/mine/4f4w) | Y-family DNA polymerase chimera Dbh-Dpo4-Dpo4 #1 | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*GP*GP*C)-3'), ... | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2012-05-11 | Release date: | 2013-01-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure, 21, 2013
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4F4Y
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![BU of 4f4y by Molmil](/molmil-images/mine/4f4y) | Y-family DNA polymerase chimera Dbh-Dpo4-Dbh | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*GP*GP*GP*CP*CP*C)-3'), ... | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2012-05-11 | Release date: | 2013-01-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.338 Å) | Cite: | Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure, 21, 2013
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4F4Z
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![BU of 4f4z by Molmil](/molmil-images/mine/4f4z) | Y-family DNA polymerase chimera Dpo4-Dpo4-Dbh | Descriptor: | CALCIUM ION, DNA (5'-D(*AP*GP*GP*GP*GP*GP*AP*AP*GP*CP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*GP*CP*CP*CP*GP*GP*CP*TP*TP*CP*CP*CP*CP*CP*T)-3'), ... | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2012-05-11 | Release date: | 2013-01-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.305 Å) | Cite: | Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure, 21, 2013
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4F50
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![BU of 4f50 by Molmil](/molmil-images/mine/4f50) | Y-family DNA polymerase chimera Dbh-Dbh-Dpo4 | Descriptor: | CALCIUM ION, DNA (5'-D(*CP*CP*GP*CP*CP*T*GP*GP*CP*TP*TP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*AP*AP*GP*CP*CP*GP*GP*C)-3'), ... | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2012-05-11 | Release date: | 2013-01-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.215 Å) | Cite: | Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure, 21, 2013
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4NLG
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![BU of 4nlg by Molmil](/molmil-images/mine/4nlg) | Y-family DNA polymerase chimera Dbh-Dpo4(243-245)-Dbh | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*GP*GP*G)-3', 5'-D(*TP*TP*AP*CP*GP*CP*CP*CP*TP*GP*AP*TP*CP*AP*GP*TP*GP*CP*C)-3', ... | Authors: | Mukherjee, P, Wilson, R.C, Pata, J.D. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Three Residues of the Interdomain Linker Determine the Conformation and Single-base Deletion Fidelity of Y-family Translesion Polymerases. J.Biol.Chem., 289, 2014
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5W5A
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![BU of 5w5a by Molmil](/molmil-images/mine/5w5a) | Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c) | Descriptor: | CHLORIDE ION, HTH-type transcriptional regulator Cmr, SULFATE ION | Authors: | Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A. | Deposit date: | 2017-06-14 | Release date: | 2017-12-13 | Last modified: | 2019-01-09 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria. Nucleic Acids Res., 46, 2018
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5W5B
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![BU of 5w5b by Molmil](/molmil-images/mine/5w5b) | Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c), truncated construct | Descriptor: | CHLORIDE ION, HTH-type transcriptional regulator Cmr | Authors: | Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A. | Deposit date: | 2017-06-14 | Release date: | 2017-12-13 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria. Nucleic Acids Res., 46, 2018
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3F2B
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![BU of 3f2b by Molmil](/molmil-images/mine/3f2b) | DNA Polymerase PolC from Geobacillus kaustophilus complex with DNA, dGTP, Mg and Zn | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DAP*DTP*DAP*DAP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DTP*DCP*DAP*DCP*DTP*DG)-3', 5'-D(*DCP*DAP*DGP*DTP*DGP*DAP*DGP*DAP*DCP*DGP*DGP*DGP*DCP*DAP*DAP*DCP*DC)-3', ... | Authors: | Davies, D.R, Evans, R.J, Bullard, J.M, Christensen, J, Green, L.S, Guiles, J.W, Ribble, W.K, Janjic, N, Jarvis, T.C. | Deposit date: | 2008-10-29 | Release date: | 2009-01-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structure of PolC reveals unique DNA binding and fidelity determinants. Proc.Natl.Acad.Sci.USA, 105, 2008
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3F2C
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![BU of 3f2c by Molmil](/molmil-images/mine/3f2c) | DNA Polymerase PolC from Geobacillus kaustophilus complex with DNA, dGTP and Mn | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DAP*DTP*DAP*DAP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DTP*DCP*DAP*DCP*DTP*DG)-3', 5'-D(*DCP*DAP*DGP*DTP*DGP*DAP*DGP*DAP*DCP*DGP*DGP*DGP*DCP*DAP*DAP*DCP*DC)-3', ... | Authors: | Davies, D.R, Evans, R.J, Bullard, J.M, Christensen, J, Green, L.S, Guiles, J.W, Ribble, W.K, Janjic, N, Jarvis, T.C. | Deposit date: | 2008-10-29 | Release date: | 2009-01-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of PolC reveals unique DNA binding and fidelity determinants. Proc.Natl.Acad.Sci.USA, 105, 2008
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3F2D
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![BU of 3f2d by Molmil](/molmil-images/mine/3f2d) | DNA Polymerase PolC from Geobacillus kaustophilus complex with DNA, dGTP, Mn and Zn | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DAP*DTP*DAP*DAP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DTP*DCP*DAP*DCP*DTP*DG)-3', 5'-D(*DCP*DAP*DGP*DTP*DGP*DAP*DGP*DAP*DCP*DGP*DGP*DGP*DCP*DAP*DAP*DCP*DC)-3', ... | Authors: | Davies, D.R, Evans, R.J, Bullard, J.M, Christensen, J, Green, L.S, Guiles, J.W, Ribble, W.K, Janjic, N, Jarvis, T.C. | Deposit date: | 2008-10-29 | Release date: | 2009-01-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure of PolC reveals unique DNA binding and fidelity determinants. Proc.Natl.Acad.Sci.USA, 105, 2008
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