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Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor:	ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN
Authors:	Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:	2015-08-24
Release date:	2016-05-11
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.597 Å)
Cite:	Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016

5DD0

Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor:	ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB HEAVY LIGHT, oligo peptide
Authors:	Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:	2015-08-24
Release date:	2016-05-11
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.488 Å)
Cite:	Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016

4QF1

Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
Descriptor:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
Authors:	Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:	2014-05-19
Release date:	2015-02-18
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved. Immunity, 41, 2014

7UD6

Designed Enzyme SH3-588 (Catechol O-methyltransferase catalytic domain and Src homology 3 binding domain fusion)
Descriptor:	POTASSIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Tyrosine-protein kinase Fyn,Catechol O-methyltransferase
Authors:	Ongpipattanakul, C, Nair, S.K.
Deposit date:	2022-03-18
Release date:	2023-01-11
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (2.59 Å)
Cite:	Designer installation of a substrate recruitment domain to tailor enzyme specificity. Nat.Chem.Biol., 19, 2023

8CSA

Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 3-RBD-Down conformation (S-GSAS-D614G-K417N-E484K-N501Y)
Descriptor:	Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2022-05-12
Release date:	2022-07-20
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (3.84 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity Science, 2021

6XRJ

Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
Descriptor:	DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
Authors:	Manne, K, Nicely, N.I, Acharya, P.
Deposit date:	2020-07-13
Release date:	2020-12-30
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (3.15 Å)
Cite:	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

6X2B

SARS-CoV-2 u1S2q 2-RBD Up Spike Protein Trimer
Descriptor:	Spike glycoprotein
Authors:	Henderson, R, Acharya, P.
Deposit date:	2020-05-20
Release date:	2020-05-27
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (3.6 Å)
Cite:	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

6X2C

SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer
Descriptor:	Spike glycoprotein
Authors:	Henderson, R, Acharya, P.
Deposit date:	2020-05-20
Release date:	2020-05-27
Last modified:	2024-10-16
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

7M0J

SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer - asymmetric refinement
Descriptor:	Spike glycoprotein
Authors:	Henderson, R, Acharya, P.
Deposit date:	2021-03-11
Release date:	2021-03-31
Last modified:	2024-10-09
Method:	ELECTRON MICROSCOPY (3.52 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation and antigenicity. Biorxiv, 2021

6X2A

SARS-CoV-2 u1S2q 1-RBD Up Spike Protein Trimer
Descriptor:	Spike glycoprotein
Authors:	Henderson, R, Acharya, P.
Deposit date:	2020-05-20
Release date:	2020-05-27
Last modified:	2024-10-16
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

6X29

SARS-CoV-2 rS2d Down State Spike Protein Trimer
Descriptor:	Spike glycoprotein
Authors:	Henderson, R, Acharya, P.
Deposit date:	2020-05-20
Release date:	2020-05-27
Last modified:	2020-10-21
Method:	ELECTRON MICROSCOPY (2.7 Å)
Cite:	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

8VLT

Crystal structure of glycan-targeting antibody 2526 Fab bound to Mannose
Descriptor:	2526 Fab Heavy Chain, 2526 Fab Light Chain, alpha-D-mannopyranose
Authors:	Lindenberger, J, Acharya, P.
Deposit date:	2024-01-12
Release date:	2024-10-16
Method:	X-RAY DIFFRACTION (1.84 Å)
Cite:	Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral families. Plos Pathog., 20, 2024

7BH8

3H4-Fab HLA-E-VL9 co-complex
Descriptor:	3H4 Fab heavy chain, 3H4 Fab light chain, Beta-2-microglobulin, ...
Authors:	Walters, L.C, Rozbesky, D.
Deposit date:	2021-01-10
Release date:	2022-04-13
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity. Commun Biol, 5, 2022

7LYK

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 2-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (3.65 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYL

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the RBD-down conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.72 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYQ

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.34 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYO

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (3.32 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYP

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (4.05 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYN

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2024-10-16
Method:	ELECTRON MICROSCOPY (3.32 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

8SAW

CryoEM structure of DH270.UCA.G57R-CH848.10.17DT
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.SOSIP.664 gp120A, CH848.3.D0949.10.17chim.6R.SOSIP.664 gp41, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-02
Release date:	2023-04-19
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SAN

CryoEM structure of VRC01-CH848.0836.10
Descriptor:	CH848.0836.10 gp120, CH848.0836.10 gp41, VCR01 variable heavy chain, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-01
Release date:	2023-04-19
Last modified:	2023-05-31
Method:	ELECTRON MICROSCOPY (4.6 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SAQ

CryoEM structure of DH270.6-CH848.0526.25
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.0526.25 gp120, CH848.0526.25 gp41, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-01
Release date:	2023-04-19
Last modified:	2023-05-31
Method:	ELECTRON MICROSCOPY (3.9 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SAU

CryoEM structure of DH270.4-CH848.10.17
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-02
Release date:	2023-04-19
Last modified:	2024-10-09
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SB2

CryoEM structure of DH270.I2-CH848.10.17
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-02
Release date:	2023-04-19
Last modified:	2024-10-30
Method:	ELECTRON MICROSCOPY (3.5 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SB0

CryoEM structure of DH270.I4.6-CH848.10.17
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-02
Release date:	2023-04-19
Last modified:	2023-05-31
Method:	ELECTRON MICROSCOPY (4.2 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

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Total results:	157
Displayed results:	25
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