2AN7
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![BU of 2an7 by Molmil](/molmil-images/mine/2an7) | Solution structure of the bacterial antidote ParD | Descriptor: | Protein parD | Authors: | Oberer, M, Zangger, K, Gruber, K, Keller, W. | Deposit date: | 2005-08-11 | Release date: | 2006-09-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The solution structure of ParD, the antidote of the ParDE toxin antitoxin module, provides the structural basis for DNA and toxin binding. Protein Sci., 16, 2007
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3ZNR
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![BU of 3znr by Molmil](/molmil-images/mine/3znr) | HDAC7 bound with inhibitor TMP269 | Descriptor: | HISTONE DEACETYLASE 7, N-{[4-(4-phenyl-1,3-thiazol-2-yl)tetrahydro-2H-pyran-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ... | Authors: | Lobera, m, madauss, k, pohlhaus, d, trump, r, nolan, m. | Deposit date: | 2013-02-15 | Release date: | 2013-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group Nat.Chem.Biol., 9, 2013
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3ZNS
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![BU of 3zns by Molmil](/molmil-images/mine/3zns) | HDAC7 bound with TFMO inhibitor tmp942 | Descriptor: | HISTONE DEACETYLASE 7, N-{[1-methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperidin-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ... | Authors: | Lobera, M, Madauss, K.P, Pohlhaus, D.T, Trump, R.P, Nolan, M.A. | Deposit date: | 2013-02-15 | Release date: | 2013-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group Nat.Chem.Biol., 9, 2013
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1U47
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![BU of 1u47 by Molmil](/molmil-images/mine/1u47) | cytosine-8-Oxoguanine base pair at the polymerase active site | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
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1XC8
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![BU of 1xc8 by Molmil](/molmil-images/mine/1xc8) | CRYSTAL STRUCTURE COMPLEX BETWEEN THE WILD-TYPE LACTOCOCCUS LACTIS FPG (MUTM) AND A FAPY-DG CONTAINING DNA | Descriptor: | 5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', Formamidopyrimidine-DNA glycosylase, ... | Authors: | Coste, F, Ober, M, Carell, T, Boiteux, S, Zelwer, C, Castaing, B. | Deposit date: | 2004-09-01 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase. J.Biol.Chem., 279, 2004
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6FL1
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![BU of 6fl1 by Molmil](/molmil-images/mine/6fl1) | Crystal structure of the complex between the Lactococcus lactis FPG mutant T221P and a Fapy-dG containing DNA | Descriptor: | DNA (5'-D(*CP*TP*CP*TP*TP*TP(FOX)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Coste, F, Castaing, B, Ober, M, Carell, T. | Deposit date: | 2018-01-25 | Release date: | 2019-02-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the complex between the Lactococcus lactis FPG mutant T221P and a Fapy-dG containing DNA To Be Published
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1TDZ
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![BU of 1tdz by Molmil](/molmil-images/mine/1tdz) | Crystal Structure Complex Between the Lactococcus Lactis FPG (Mutm) and a FAPY-dG Containing DNA | Descriptor: | 5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', GLYCEROL, ... | Authors: | Coste, F, Ober, M, Carell, T, Boiteux, S, Zelwer, C, Castaing, B. | Deposit date: | 2004-05-24 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase J.Biol.Chem., 279, 2004
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1U49
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![BU of 1u49 by Molmil](/molmil-images/mine/1u49) | Adenine-8oxoguanine mismatch at the polymerase active site | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
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1U48
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![BU of 1u48 by Molmil](/molmil-images/mine/1u48) | Extension of a cytosine-8-oxoguanine base pair | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
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1U45
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![BU of 1u45 by Molmil](/molmil-images/mine/1u45) | 8oxoguanine at the pre-insertion site of the polymerase active site | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
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1U4B
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![BU of 1u4b by Molmil](/molmil-images/mine/1u4b) | Extension of an adenine-8oxoguanine mismatch | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
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6EIC
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![BU of 6eic by Molmil](/molmil-images/mine/6eic) | Crystal structure of Rv0183, a Monoglyceride Lipase from Mycobacterium Tuberculosis | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Mycobacterium Tuberculosis Monoglyceride Lipase, NITRATE ION, ... | Authors: | Aschauer, P, Pavkov-Keller, T, Oberer, M. | Deposit date: | 2017-09-19 | Release date: | 2018-06-27 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition. Sci Rep, 8, 2018
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7OZM
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![BU of 7ozm by Molmil](/molmil-images/mine/7ozm) | Crystal Structure of mtbMGL K74A (Closed Cap Conformation) | Descriptor: | ISOPROPYL ALCOHOL, Monoacylglycerol lipase | Authors: | Grininger, C, Aschauer, P, Pavkov-Keller, T, Oberer, M. | Deposit date: | 2021-06-28 | Release date: | 2021-09-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural Changes in the Cap of Rv0183/mtbMGL Modulate the Shape of the Binding Pocket. Biomolecules, 11, 2021
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7P0Y
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![BU of 7p0y by Molmil](/molmil-images/mine/7p0y) | Crystal Structure of mtbMGL K74A (Substrate Analog Complex) | Descriptor: | 1-[butyl(fluoranyl)phosphoryl]oxyhexadecane, Monoacylglycerol lipase | Authors: | Grininger, C, Aschauer, P, Pavkov-Keller, T, Oberer, M. | Deposit date: | 2021-06-30 | Release date: | 2021-09-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Changes in the Cap of Rv0183/mtbMGL Modulate the Shape of the Binding Pocket. Biomolecules, 11, 2021
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2LYC
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![BU of 2lyc by Molmil](/molmil-images/mine/2lyc) | Structure of C-terminal domain of Ska1 | Descriptor: | Spindle and kinetochore-associated protein 1 homolog | Authors: | Boeszoermenyi, A, Schmidt, J.C, Markus, M, Oberer, M, Cheeseman, I.M, Wagner, G, Arthanari, H. | Deposit date: | 2012-09-14 | Release date: | 2012-10-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The kinetochore-bound ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments. Dev.Cell, 23, 2012
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2H3C
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![BU of 2h3c by Molmil](/molmil-images/mine/2h3c) | Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA | Descriptor: | 5'-D(P*AP*TP*AP*TP*GP*TP*AP*TP*AP*CP*CP*CP*G)-3', 5'-D(P*TP*CP*GP*GP*GP*TP*AP*TP*AP*CP*AP*TP*A)-3', CcdA | Authors: | Madl, T, Van Melderen, L, Respondek, M, Oberer, M, Keller, W, Zangger, K. | Deposit date: | 2006-05-22 | Release date: | 2006-11-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural Basis for Nucleic Acid and Toxin Recognition of the Bacterial Antitoxin CcdA J.Mol.Biol., 364, 2006
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2H3A
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![BU of 2h3a by Molmil](/molmil-images/mine/2h3a) | Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA | Descriptor: | 5'-D(P*AP*TP*AP*TP*GP*TP*AP*TP*AP*CP*CP*CP*G)-3', 5'-D(P*TP*CP*GP*GP*GP*TP*AP*TP*AP*CP*AP*TP*A)-3', CcdA | Authors: | Madl, T, Van Melderen, L, Respondek, M, Oberer, M, Keller, W, Zangger, K. | Deposit date: | 2006-05-22 | Release date: | 2006-11-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural Basis for Nucleic Acid and Toxin Recognition of the Bacterial Antitoxin CcdA J.Mol.Biol., 364, 2006
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4ZWN
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![BU of 4zwn by Molmil](/molmil-images/mine/4zwn) | Crystal Structure of a Soluble Variant of the Monoglyceride Lipase from Saccharomyces Cerevisiae | Descriptor: | Monoglyceride lipase, NITRATE ION, SODIUM ION, ... | Authors: | Aschauer, P, Rengachari, S, Gruber, K, Oberer, M. | Deposit date: | 2015-05-19 | Release date: | 2016-04-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.491 Å) | Cite: | Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p. Biochim.Biophys.Acta, 1861, 2016
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2ADL
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![BU of 2adl by Molmil](/molmil-images/mine/2adl) | Solution structure of the bacterial antitoxin CcdA: Implications for DNA and toxin binding | Descriptor: | CcdA | Authors: | Madl, T, VanMelderen, L, Oberer, M, Keller, W, Khatai, L, Zangger, K. | Deposit date: | 2005-07-20 | Release date: | 2006-08-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA J.Mol.Biol., 364, 2006
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2ADN
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![BU of 2adn by Molmil](/molmil-images/mine/2adn) | Solution structure of the bacterial antitoxin CcdA: Implications for DNA and toxin binding | Descriptor: | CcdA | Authors: | Madl, T, VanMelderen, L, Oberer, M, Keller, W, Khatai, L, Zangger, K. | Deposit date: | 2005-07-20 | Release date: | 2006-08-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA J.Mol.Biol., 364, 2006
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4ZXF
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![BU of 4zxf by Molmil](/molmil-images/mine/4zxf) | Crystal Structure of a Soluble Variant of Monoglyceride Lipase from Saccharomyces Cerevisiae in Complex with a Substrate Analog | Descriptor: | 1-{3-[(R)-hydroxy(octadecyloxy)phosphoryl]propyl}triaza-1,2-dien-2-ium, Monoglyceride lipase, NITRATE ION, ... | Authors: | Aschauer, P, Lichtenegger, J, Rengachari, S, Gruber, K, Oberer, M. | Deposit date: | 2015-05-20 | Release date: | 2016-05-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p. Biochim.Biophys.Acta, 1861, 2016
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8AXC
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![BU of 8axc by Molmil](/molmil-images/mine/8axc) | Crystal structure of mouse Ces2c | Descriptor: | Acylcarnitine hydrolase, CHLORIDE ION, NICOTINAMIDE, ... | Authors: | Eisner, H, Riegler-Berket, L, Rodriguez Gamez, C, Sagmeister, T, Chalhoub, G, Darnhofer, B, Panikkaveetil Jawaharlal, J, Birner-Gruenberger, R, Pavkov-Keller, T, Haemmerle, G, Schoiswohl, G, Oberer, M. | Deposit date: | 2022-08-31 | Release date: | 2022-11-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1. Int J Mol Sci, 23, 2022
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3RLI
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![BU of 3rli by Molmil](/molmil-images/mine/3rli) | Crystal structure of monoacylglycerol lipase from Bacillus sp. H257 in complex with PMSF | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, Thermostable monoacylglycerol lipase, phenylmethanesulfonic acid | Authors: | Rengachari, S, Bezerra, G.A, Gruber, K, Oberer, M. | Deposit date: | 2011-04-19 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.854 Å) | Cite: | The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes. Biochim.Biophys.Acta, 1821, 2012
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3RM3
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![BU of 3rm3 by Molmil](/molmil-images/mine/3rm3) | Crystal structure of monoacylglycerol lipase from Bacillus sp. H257 | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, Thermostable monoacylglycerol lipase | Authors: | Rengachari, S, Bezerra, G.A, Gruber, K, Oberer, M. | Deposit date: | 2011-04-20 | Release date: | 2012-05-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes. Biochim.Biophys.Acta, 1821, 2012
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4KE8
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![BU of 4ke8 by Molmil](/molmil-images/mine/4ke8) | Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with monopalmitoyl glycerol analogue | Descriptor: | Thermostable monoacylglycerol lipase, tetradecyl hydrogen (R)-(3-azidopropyl)phosphonate | Authors: | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | Deposit date: | 2013-04-25 | Release date: | 2013-09-18 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
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