4YVB
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![BU of 4yvb by Molmil](/molmil-images/mine/4yvb) | Structure of D128N streptavidin | Descriptor: | BIOTIN, Streptavidin | Authors: | Baugh, L, Le Trong, I, Stayton, P.S, Stenkamp, R.E, Lybrand, T.P. | Deposit date: | 2015-03-19 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.351 Å) | Cite: | A Streptavidin Binding Site Mutation Yields an Unexpected Result To Be Published
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3T6F
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![BU of 3t6f by Molmil](/molmil-images/mine/3t6f) | Biotin complex of Y54F core streptavidin | Descriptor: | BIOTIN, BIOTIN-D-SULFOXIDE, GLYCEROL, ... | Authors: | Baugh, L, Le Trong, I, Cerutti, D.S, Mehta, N, Gulich, S, Stayton, P.S, Stenkamp, R.E, Lybrand, T.P. | Deposit date: | 2011-07-28 | Release date: | 2011-12-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Second-Contact Shell Mutation Diminishes Streptavidin-Biotin Binding Affinity through Transmitted Effects on Equilibrium Dynamics. Biochemistry, 51, 2012
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3T6L
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![BU of 3t6l by Molmil](/molmil-images/mine/3t6l) | Y54F mutant of core streptavidin | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Streptavidin | Authors: | Baugh, L, Le Trong, I, Stayton, P.S, Stenkamp, R.E, Lybrand, T.P. | Deposit date: | 2011-07-28 | Release date: | 2011-12-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Second-Contact Shell Mutation Diminishes Streptavidin-Biotin Binding Affinity through Transmitted Effects on Equilibrium Dynamics. Biochemistry, 51, 2012
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4GD9
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![BU of 4gd9 by Molmil](/molmil-images/mine/4gd9) | Circular Permuted Streptavidin N49/G48 | Descriptor: | BIOTIN, SULFATE ION, Streptavidin | Authors: | Le Trong, I, Chu, V, Xing, Y, Lybrand, T.P, Stayton, P.S, Stenkamp, R.E. | Deposit date: | 2012-07-31 | Release date: | 2013-06-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural consequences of cutting a binding loop: two circularly permuted variants of streptavidin. Acta Crystallogr.,Sect.D, 69, 2013
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4GDA
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![BU of 4gda by Molmil](/molmil-images/mine/4gda) | Circular Permuted Streptavidin A50/N49 | Descriptor: | BIOTIN, ETHANOL, GLYCEROL, ... | Authors: | Le Trong, I, Chu, V, Xing, Y, Lybrand, T.P, Stayton, P.S, Stenkamp, R.E. | Deposit date: | 2012-07-31 | Release date: | 2013-06-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Structural consequences of cutting a binding loop: two circularly permuted variants of streptavidin. Acta Crystallogr.,Sect.D, 69, 2013
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3MG5
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![BU of 3mg5 by Molmil](/molmil-images/mine/3mg5) | Core-streptavidin mutant F130L in complex with biotin | Descriptor: | BIOTIN, GLYCEROL, Streptavidin | Authors: | Le Trong, I, Baugh, L, Stayton, P.S, Lybrand, T.P, Stenkamp, R.E. | Deposit date: | 2010-04-05 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | A distal point mutation in the streptavidin-biotin complex preserves structure but diminishes binding affinity: experimental evidence of electronic polarization effects? Biochemistry, 49, 2010
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3RY1
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![BU of 3ry1 by Molmil](/molmil-images/mine/3ry1) | Wild-type core streptavidin at atomic resolution | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Streptavidin | Authors: | Stenkamp, R.E, Wang, Z, Le Trong, I, Stayton, P.S, Lybrand, T.P. | Deposit date: | 2011-05-10 | Release date: | 2011-08-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Streptavidin and its biotin complex at atomic resolution. Acta Crystallogr.,Sect.D, 67, 2011
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3RY2
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![BU of 3ry2 by Molmil](/molmil-images/mine/3ry2) | Wild-type core streptavidin-biotin complex at atomic resolution | Descriptor: | BIOTIN, GLYCEROL, Streptavidin | Authors: | Stenkamp, R.E, Le Trong, I, Stayton, P.S, Lybrand, T.P. | Deposit date: | 2011-05-10 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Streptavidin and its biotin complex at atomic resolution. Acta Crystallogr.,Sect.D, 67, 2011
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8SV4
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![BU of 8sv4 by Molmil](/molmil-images/mine/8sv4) | 7-Deazapurines and 5-Halogenpyrimidine DNA duplex | Descriptor: | 1,2-ETHANEDIOL, 2-[2-(2-ethoxyethoxy)ethoxy]ethanol, ACETATE ION, ... | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2023-05-15 | Release date: | 2023-10-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry. Biochemistry, 62, 2023
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8SV3
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![BU of 8sv3 by Molmil](/molmil-images/mine/8sv3) | 7-Deazapurines and 5-Halogenpyrimidine DNA duplex | Descriptor: | GLYCEROL, MAGNESIUM ION, Modified DNA, ... | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2023-05-15 | Release date: | 2023-10-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry. Biochemistry, 62, 2023
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5DO4
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![BU of 5do4 by Molmil](/molmil-images/mine/5do4) | Thrombin-RNA aptamer complex | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2015-09-10 | Release date: | 2016-09-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.859 Å) | Cite: | Evoking picomolar binding in RNA by a single phosphorodithioate linkage. Nucleic Acids Res., 44, 2016
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7UCR
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![BU of 7ucr by Molmil](/molmil-images/mine/7ucr) | Joint X-ray/neutron structure of the Sarcin-Ricin loop RNA | Descriptor: | SULFATE ION, Sarcin-Ricin loop RNA | Authors: | Harp, J.M, Egli, M.E, Pallan, P.S, Coates, L. | Deposit date: | 2022-03-17 | Release date: | 2022-07-20 | Last modified: | 2024-04-03 | Method: | NEUTRON DIFFRACTION (1 Å), X-RAY DIFFRACTION | Cite: | Cryo neutron crystallography demonstrates influence of RNA 2'-OH orientation on conformation, sugar pucker and water structure. Nucleic Acids Res., 50, 2022
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7JJE
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![BU of 7jje by Molmil](/molmil-images/mine/7jje) | |
7JJF
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![BU of 7jjf by Molmil](/molmil-images/mine/7jjf) | Sarcin-ricin loop with modified residue. | Descriptor: | MAGNESIUM ION, RNA/DNA (27-mer) | Authors: | Harp, J.M, Pallan, P.S, Egli, M. | Deposit date: | 2020-07-25 | Release date: | 2020-12-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Incorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost. Biochemistry, 59, 2020
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7JJD
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1SWS
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![BU of 1sws by Molmil](/molmil-images/mine/1sws) | CORE-STREPTAVIDIN MUTANT D128A AT PH 4.5 | Descriptor: | PROTEIN (STREPTAVIDIN) | Authors: | Freitag, S, Chu, V, Le Trong, I, Klumb, L.A, To, R, Stayton, P.S, Stenkamp, R.E. | Deposit date: | 1998-10-22 | Release date: | 1999-07-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural snapshot of an intermediate on the streptavidin-biotin dissociation pathway. Proc.Natl.Acad.Sci.USA, 96, 1999
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1SWT
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![BU of 1swt by Molmil](/molmil-images/mine/1swt) | CORE-STREPTAVIDIN MUTANT D128A IN COMPLEX WITH BIOTIN AT PH 4.5 | Descriptor: | BIOTIN, PROTEIN (STREPTAVIDIN) | Authors: | Freitag, S, Le Trong, I, Chu, V, Klumb, L.A, Stayton, P.S, Stenkamp, R.E. | Deposit date: | 1998-10-22 | Release date: | 1999-07-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural snapshot of an intermediate on the streptavidin-biotin dissociation pathway. Proc.Natl.Acad.Sci.USA, 96, 1999
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