4Q0C
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![BU of 4q0c by Molmil](/molmil-images/mine/4q0c) | 3.1 A resolution crystal structure of the B. pertussis BvgS periplasmic domain | Descriptor: | Virulence sensor protein BvgS | Authors: | Dupre, E, Herrou, J, Lensink, M.F, Wintjens, R, Lebedev, A, Crosson, S, Villeret, V, Locht, C, Antoine, R, Jacob-Dubuisson, F. | Deposit date: | 2014-04-01 | Release date: | 2015-02-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Virulence Regulation with Venus Flytrap Domains: Structure and Function of the Periplasmic Moiety of the Sensor-Kinase BvgS. Plos Pathog., 11, 2015
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6YHW
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![BU of 6yhw by Molmil](/molmil-images/mine/6yhw) | Co-crystals in the P212121 space group, of a beta-cyclodextrin spacered by triazole heptyl from alpha-D-mannose, with FimH lectin at 2.00 A resolution. | Descriptor: | 2H-1,2,3-TRIAZOL-4-YLMETHANOL, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), FimH, ... | Authors: | de Ruyck, J, Bouckaert, J. | Deposit date: | 2020-03-31 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.962 Å) | Cite: | The Antiadhesive Strategy in Crohn's Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut. Chembiochem, 17, 2016
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8BXY
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![BU of 8bxy by Molmil](/molmil-images/mine/8bxy) | FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group | Descriptor: | NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ... | Authors: | Bridot, C, Bouckaert, J, Krammer, E.-M. | Deposit date: | 2022-12-11 | Release date: | 2023-04-12 | Last modified: | 2023-04-26 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors. J.Biol.Chem., 299, 2023
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8BY3
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![BU of 8by3 by Molmil](/molmil-images/mine/8by3) | FimH lectin domain in complex with oligomannose-6 | Descriptor: | NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ... | Authors: | Bouckaert, J, Bourenkov, G.P. | Deposit date: | 2022-12-11 | Release date: | 2023-04-12 | Last modified: | 2023-04-26 | Method: | X-RAY DIFFRACTION (3.186 Å) | Cite: | Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors. J.Biol.Chem., 299, 2023
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7BHD
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![BU of 7bhd by Molmil](/molmil-images/mine/7bhd) | FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group | Descriptor: | NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ... | Authors: | Bridot, C, Bouckaert, J, Krammer, E.-M. | Deposit date: | 2021-01-11 | Release date: | 2022-07-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors. J.Biol.Chem., 299, 2023
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8BVD
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![BU of 8bvd by Molmil](/molmil-images/mine/8bvd) | FimH lectin domain in complex with mannose C-linked to quinoline | Descriptor: | (2R,3S,4R,5S,6R)-2-(hydroxymethyl)-6-[(E)-3-quinolin-6-ylprop-2-enyl]oxane-3,4,5-triol, Type 1 fimbrin D-mannose specific adhesin | Authors: | Bouckaert, J, Bridot, C. | Deposit date: | 2022-12-03 | Release date: | 2023-02-15 | Last modified: | 2023-03-08 | Method: | X-RAY DIFFRACTION (2.995 Å) | Cite: | Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists. Pharmaceutics, 15, 2023
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6ZJ8
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![BU of 6zj8 by Molmil](/molmil-images/mine/6zj8) | |
7QUO
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![BU of 7quo by Molmil](/molmil-images/mine/7quo) | FimH lectin domain in complex with oligomannose-6 | Descriptor: | FimH, NICKEL (II) ION, SULFATE ION, ... | Authors: | Bouckaert, J, Bourenkov, G.P. | Deposit date: | 2022-01-18 | Release date: | 2023-02-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors J.Biol.Chem., 299, 2023
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4CA4
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![BU of 4ca4 by Molmil](/molmil-images/mine/4ca4) | Crystal structure of FimH lectin domain with the Tyr48Ala mutation, in complex with heptyl alpha-D-mannopyrannoside | Descriptor: | FIMH, heptyl alpha-D-mannopyranoside | Authors: | Rabbani, S, Bouckaert, J, Zalewski, A, Preston, R, Eid, S, Thompson, A, Puorger, C, Glockshuber, R, Ernst, B. | Deposit date: | 2013-10-06 | Release date: | 2014-10-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding. IUCrJ, 4, 2017
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6EW4
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6EW2
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![BU of 6ew2 by Molmil](/molmil-images/mine/6ew2) | Human myelin protein P2 F57A mutant, tetragonal crystal form | Descriptor: | CHLORIDE ION, Myelin P2 protein, PALMITIC ACID | Authors: | Laulumaa, S, Lehtimaki, M, Kursula, P. | Deposit date: | 2017-11-03 | Release date: | 2018-07-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.588 Å) | Cite: | Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the beta barrel in fatty acid binding proteins. BMC Struct. Biol., 18, 2018
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6EW5
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5AAL
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![BU of 5aal by Molmil](/molmil-images/mine/5aal) | Complex of the FimH lectin with a C-linked para-biphenyl ethylene alpha-D-mannoside in soaked trigonal crystals at 2.45 A resolution | Descriptor: | (2R,3S,4R,5S,6R)-2-(hydroxymethyl)-6-[(Z)-3-(4-phenylphenyl)prop-2-enyl]oxane-3,4,5-triol, FIMH, NICKEL (II) ION, ... | Authors: | De Ruyck, J, Bouckaert, J. | Deposit date: | 2015-07-27 | Release date: | 2016-03-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structures of C-Mannosylated Anti-Adhesives Bound to the Type 1 Fimbrial Fimh Adhesin Iucrj, 3, 2016
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5ABZ
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![BU of 5abz by Molmil](/molmil-images/mine/5abz) | Complex of the FimH lectin with a C-linked naphtyl alpha-D-mannoside in soaked trigonal crystals at 2.40 A resolution | Descriptor: | (2R,3S,4R,5S,6R)-2-(HYDROXYMETHYL)-6-[3-(NAPHTHALEN-1-YL)PROPYL]OXANE-3,4,5-TRIOL, FIMH, NICKEL (II) ION | Authors: | de Ruyck, J, Bouckaert, J. | Deposit date: | 2015-08-10 | Release date: | 2016-03-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of C-Mannosylated Anti-Adhesives Bound to the Type 1 Fimbrial Fimh Adhesin Iucrj, 3, 2016
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5AAP
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5FX3
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![BU of 5fx3 by Molmil](/molmil-images/mine/5fx3) | |
5FS5
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5FWR
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![BU of 5fwr by Molmil](/molmil-images/mine/5fwr) | |