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7BBD
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BU of 7bbd by Molmil
Crystal structure of monoubiquitinated TRIM21 RING (Ub-RING) In complex with ubiquitin charged Ube2N (Ube2N~Ub) and Ube2V2
Descriptor: Polyubiquitin-B,E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Kiss, L, Neuhaus, D, James, L.C.
Deposit date:2020-12-17
Release date:2021-01-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.
Nat Commun, 12, 2021
7BBF
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BU of 7bbf by Molmil
Crystal structure of ubiquitin charged Ube2N (Ube2N~Ub) in complex with Ube2V2
Descriptor: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Kiss, L, Neuhaus, D, James, L.C.
Deposit date:2020-12-17
Release date:2021-01-27
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.
Nat Commun, 12, 2021
6S53
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BU of 6s53 by Molmil
Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ...
Authors:Kiss, L, Boland, A, Neuhaus, D, James, L.C.
Deposit date:2019-06-30
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Nat Commun, 10, 2019
8A58
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BU of 8a58 by Molmil
X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W
Descriptor: E3 ubiquitin-protein ligase TRIM21, Ubiquitin-conjugating enzyme E2 W, ZINC ION
Authors:James, L.C, Kiss, L.
Deposit date:2022-06-14
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Nat Commun, 14, 2023
2LPB
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BU of 2lpb by Molmil
Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15
Descriptor: General control protein GCN4, Mediator of RNA polymerase II transcription subunit 15
Authors:Brzovic, P.S, Heikaus, C.C, Kisselev, L, Vernon, R, Herbig, E, Pacheco, D, Warfield, L, Littlefield, P, Baker, D, Klevit, R.E, Hahn, S.
Deposit date:2012-02-07
Release date:2012-02-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Mol.Cell, 44, 2011
7Q72
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BU of 7q72 by Molmil
Structure of Pla1 in complex with Red1
Descriptor: NURS complex subunit red1, Poly(A) polymerase pla1
Authors:Soni, K, Wild, K, Sinning, I.
Deposit date:2021-11-09
Release date:2022-12-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Nat Commun, 14, 2023
7Q73
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BU of 7q73 by Molmil
Structure of Pla1 apo
Descriptor: GLYCEROL, Poly(A) polymerase pla1
Authors:Soni, K, Wild, K, Sinning, I.
Deposit date:2021-11-09
Release date:2022-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Nat Commun, 14, 2023
7Q74
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BU of 7q74 by Molmil
Structure of Pla1 apo, with a C-terminal deletion
Descriptor: Poly(A) polymerase pla1
Authors:Soni, K, Wild, K, Sinning, I.
Deposit date:2021-11-09
Release date:2022-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Nat Commun, 14, 2023
1DT9
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BU of 1dt9 by Molmil
THE CRYSTAL STRUCTURE OF HUMAN EUKARYOTIC RELEASE FACTOR ERF1-MECHANISM OF STOP CODON RECOGNITION AND PEPTIDYL-TRNA HYDROLYSIS
Descriptor: PROTEIN (EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1)
Authors:Frolova, L.
Deposit date:2000-01-12
Release date:2000-02-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis.
Cell(Cambridge,Mass.), 100, 2000

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数据于2024-11-06公开中

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