6B2U
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![BU of 6b2u by Molmil](/molmil-images/mine/6b2u) | Crystal structure of Xanthomonas campestris OleA H285N with Cerulenin | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Jensen, M.R, Goblirsch, B.R, Esler, M.A, Christenson, J.K, Mohamed, F.A, Wackett, L.P, Wilmot, C.M. | Deposit date: | 2017-09-20 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | The role of OleA His285 in substrate coordination of long-chain acyl-CoA To be published
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6B2S
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![BU of 6b2s by Molmil](/molmil-images/mine/6b2s) | Crystal structure of Xanthomonas campestris OleA H285N | Descriptor: | 3-oxoacyl-[ACP] synthase III, GLYCEROL, PHOSPHATE ION | Authors: | Jensen, M.R, Goblirsch, B.R, Esler, M.A, Christenson, J.K, Mohamed, F.A, Wackett, L.P, Wilmot, C.M. | Deposit date: | 2017-09-20 | Release date: | 2018-02-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The role of OleA His285 in orchestration of long-chain acyl-coenzyme A substrates. FEBS Lett., 592, 2018
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6B2R
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![BU of 6b2r by Molmil](/molmil-images/mine/6b2r) | Crystal structure of Xanthomonas campestris OleA H285A | Descriptor: | 3-oxoacyl-[ACP] synthase III, GLYCEROL | Authors: | Jensen, M.R, Goblirsch, B.R, Esler, M.A, Christenson, J.K, Mohamed, F.A, Wackett, L.P, Wilmot, C.M. | Deposit date: | 2017-09-20 | Release date: | 2018-02-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | The role of OleA His285 in orchestration of long-chain acyl-coenzyme A substrates. FEBS Lett., 592, 2018
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6B2T
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![BU of 6b2t by Molmil](/molmil-images/mine/6b2t) | Crystal structure of Xanthomonas campestris OleA H285D | Descriptor: | 3-oxoacyl-[ACP] synthase III, GLYCEROL, PHOSPHATE ION | Authors: | Jensen, M.R, Goblirsch, B.R, Esler, M.A, Christenson, J.K, Mohamed, F.A, Wackett, L.P, Wilmot, C.M. | Deposit date: | 2017-09-20 | Release date: | 2018-02-28 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The role of OleA His285 in orchestration of long-chain acyl-coenzyme A substrates. FEBS Lett., 592, 2018
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5VXD
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![BU of 5vxd by Molmil](/molmil-images/mine/5vxd) | |
5VXG
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![BU of 5vxg by Molmil](/molmil-images/mine/5vxg) | Crystal structure of Xanthomonas campestris OleA E117Q bound with Cerulenin | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Jensen, M.R, Wilmot, C.M. | Deposit date: | 2017-05-23 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J., 474, 2017
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5VXI
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![BU of 5vxi by Molmil](/molmil-images/mine/5vxi) | Crystal structure of Xanthomonas campestris OleA E117D bound with Cerulenin | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Jensen, M.R, Wilmot, C.M. | Deposit date: | 2017-05-23 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J., 474, 2017
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5VXF
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5VXH
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![BU of 5vxh by Molmil](/molmil-images/mine/5vxh) | Crystal structure of Xanthomonas campestris OleA E117D | Descriptor: | 3-oxoacyl-[ACP] synthase III, GLYCEROL, PHOSPHATE ION | Authors: | Jensen, M.R, Wilmot, C.M. | Deposit date: | 2017-05-23 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J., 474, 2017
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5VXE
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![BU of 5vxe by Molmil](/molmil-images/mine/5vxe) | Crystal structure of Xanthomonas campestris OleA E117A bound with Cerulenin | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Jensen, M.R, Wilmot, C.M. | Deposit date: | 2017-05-23 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J., 474, 2017
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3SXT
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![BU of 3sxt by Molmil](/molmil-images/mine/3sxt) | |
3SWS
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![BU of 3sws by Molmil](/molmil-images/mine/3sws) | |
3RN1
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4XW2
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![BU of 4xw2 by Molmil](/molmil-images/mine/4xw2) | Structural basis for simvastatin competitive antagonism of complement receptor 3 | Descriptor: | Integrin alpha-M, MAGNESIUM ION, Simvastatin acid | Authors: | Bajic, G, Jensen, M.R, Vorup-Jensen, T, Andersen, G.R. | Deposit date: | 2015-01-28 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural Basis for Simvastatin Competitive Antagonism of Complement Receptor 3. J.Biol.Chem., 291, 2016
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8RPP
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![BU of 8rpp by Molmil](/molmil-images/mine/8rpp) | |
7NYO
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![BU of 7nyo by Molmil](/molmil-images/mine/7nyo) | Mutant A541L of SH3 domain of JNK-interacting Protein 1 (JIP1) | Descriptor: | 1,2-ETHANEDIOL, SH3 domain of JNK-interacting Protein 1 (JIP1), SULFATE ION, ... | Authors: | Perez, L.M, Ielasi, F.S, Palencia, A, Jensen, M.R. | Deposit date: | 2021-03-23 | Release date: | 2021-12-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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7NZC
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7NYK
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7NYM
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![BU of 7nym by Molmil](/molmil-images/mine/7nym) | Mutant V517A - SH3 domain of JNK-interacting Protein 1 (JIP1) | Descriptor: | HEXAETHYLENE GLYCOL, PHOSPHATE ION, SH3 domain of JNK-interacting Protein 1 (JIP1), ... | Authors: | Perez, L.M, Ielasi, F.S, Palencia, A, Jensen, M.R. | Deposit date: | 2021-03-23 | Release date: | 2021-12-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.614 Å) | Cite: | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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7NZB
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![BU of 7nzb by Molmil](/molmil-images/mine/7nzb) | Mutant V517L of the SH3 domain of JNK-interacting protein 1 (JIP1) | Descriptor: | PHOSPHATE ION, SH3 domain of JNK-interacting protein 1 (JIP1), TETRAETHYLENE GLYCOL | Authors: | Perez, L.M, Ielasi, F.S, Jensen, M.R, Palencia, A. | Deposit date: | 2021-03-23 | Release date: | 2021-12-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.959 Å) | Cite: | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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7NYN
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![BU of 7nyn by Molmil](/molmil-images/mine/7nyn) | Mutant Y526A of SH3 domain of JNK-interacting Protein 1 (JIP1) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... | Authors: | Perez, L.M, Ielasi, F.S, Palencia, A, Jensen, M.R. | Deposit date: | 2021-03-23 | Release date: | 2021-12-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.537 Å) | Cite: | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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7NYL
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![BU of 7nyl by Molmil](/molmil-images/mine/7nyl) | Mutant H493A of SH3 domain of JNK-interacting Protein 1 (JIP1) | Descriptor: | SH3 domain of JNK-interacting Protein 1 (JIP1), TETRAETHYLENE GLYCOL, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | Authors: | Perez, L.M, Ielasi, F.S, Palencia, A, Jensen, M.R. | Deposit date: | 2021-03-23 | Release date: | 2021-12-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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7NZD
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![BU of 7nzd by Molmil](/molmil-images/mine/7nzd) | Fourth SH3 domain of POSH (Plenty of SH3 Domains protein) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase SH3RF1 | Authors: | Palencia, A, Bessa, L.M, Jensen, M.R. | Deposit date: | 2021-03-23 | Release date: | 2021-12-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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4CO6
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![BU of 4co6 by Molmil](/molmil-images/mine/4co6) | Crystal structure of the Nipah virus RNA free nucleoprotein- phosphoprotein complex | Descriptor: | BROMIDE ION, CHLORIDE ION, NUCLEOPROTEIN, ... | Authors: | Yabukarksi, F, Lawrence, P, Tarbouriech, N, Bourhis, J.M, Jensen, M.R, Ruigrok, R.W.H, Blackledge, M, Volchkov, V, Jamin, M. | Deposit date: | 2014-01-27 | Release date: | 2014-08-13 | Last modified: | 2014-09-17 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Structure of Nipah Virus Unassembled Nucleoprotein in Complex with its Viral Chaperone. Nat.Struct.Mol.Biol., 21, 2014
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4FCQ
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![BU of 4fcq by Molmil](/molmil-images/mine/4fcq) | Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization | Descriptor: | 4-(2,4-dimethylphenyl)-2-(methylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Heat shock protein HSP 90-alpha | Authors: | Davies, N.G, Browne, H, Davis, B, Foloppe, N, Geoffrey, S, Gibbons, B, Hart, T, Drysdale, M.J, Mansell, H, Massey, A, Matassova, N, Moore, J.D, Murray, J, Pratt, R, Ray, S, Roughley, S.D, Jensen, M.R, Schoepfer, J, Scriven, K, Simmonite, H, Stokes, S, Surgenor, A, Webb, P, Wright, L, Brough, P. | Deposit date: | 2012-05-25 | Release date: | 2012-10-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization. Bioorg.Med.Chem., 20, 2012
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