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2XSD
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BU of 2xsd by Molmil
Crystal Structure of the dimeric Oct-6 (Pou3f1) POU domain bound to palindromic MORE DNA
Descriptor: 1,2-ETHANEDIOL, 5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*AP)-3', 5'-D(*CP*CP*TP*CP*AP*TP*GP*CP*AP*TP*AP)-3', ...
Authors:Jauch, R, Choo, S.H, Ng, C.K.L, Kolatkar, P.R.
Deposit date:2010-09-28
Release date:2010-10-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Crystal Structure of the Dimeric Oct6 (POU3F1) POU Domain Bound to Palindromic More DNA.
Proteins, 79, 2011
2VI6
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BU of 2vi6 by Molmil
Crystal Structure of the Nanog Homeodomain
Descriptor: HOMEOBOX PROTEIN NANOG
Authors:Jauch, R, Ng, C.K.L, Saitakendu, K.S, Stevens, R.C, Kolatkar, P.R.
Deposit date:2007-11-28
Release date:2008-01-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure and DNA Binding of the Homeodomain of the Stem Cell Transcription Factor Nanog.
J.Mol.Biol., 376, 2008
1PZW
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BU of 1pzw by Molmil
Crystal structure of the zinc finger associated domain of the Drosophila transcription factor Grauzone
Descriptor: Transcription factor grauzone, ZINC ION
Authors:Jauch, R, Bourenkov, G.P, Chung, H.-R, Urlaub, H, Reidt, U, Jaeckle, H, Wahl, M.C.
Deposit date:2003-07-14
Release date:2003-11-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The zinc finger-associated domain of the Drosophila transcription factor grauzone is a novel zinc-coordinating protein-protein interaction module
STRUCTURE, 11, 2003
3U2B
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BU of 3u2b by Molmil
Structure of the Sox4 HMG domain bound to DNA
Descriptor: DNA (5'-D(*CP*CP*AP*GP*GP*AP*CP*AP*AP*TP*AP*GP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*TP*GP*TP*CP*CP*TP*GP*G)-3'), Transcription factor SOX-4
Authors:Jauch, R, Ng, C.K.L, Kolatkar, P.R.
Deposit date:2011-10-03
Release date:2011-12-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognition
Biochem.J., 443, 2012
2AC3
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BU of 2ac3 by Molmil
Structure of human Mnk2 Kinase Domain
Descriptor: MAP kinase-interacting serine/threonine kinase 2, ZINC ION
Authors:Jauch, R, Wahl, M.C, Netter, C, Jakel, S, Schreiter, K, Aicher, B, Jackle, H.
Deposit date:2005-07-18
Release date:2005-10-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the Mnk2 kinase domain reveal an inhibitory conformation and a zinc binding site.
Structure, 13, 2005
2AC5
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BU of 2ac5 by Molmil
Structure of human Mnk2 Kinase Domain mutant D228G
Descriptor: MAP kinase-interacting serine/threonine kinase 2, ZINC ION
Authors:Jauch, R, Wahl, M.C, Jakel, S, Schreiter, K, Aicher, B, Jackle, H.
Deposit date:2005-07-18
Release date:2005-10-04
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of the Mnk2 kinase domain reveal an inhibitory conformation and a zinc binding site.
Structure, 13, 2005
2HW7
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BU of 2hw7 by Molmil
Crystal Structure of Mnk2-D228G in complex with Staurosporine
Descriptor: MAP kinase-interacting serine/threonine-protein kinase 2, STAUROSPORINE, ZINC ION
Authors:Jauch, R, Wahl, M.C.
Deposit date:2006-08-01
Release date:2006-08-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.
Embo J., 25, 2006
2HW6
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BU of 2hw6 by Molmil
Crystal structure of Mnk1 catalytic domain
Descriptor: MAP kinase-interacting serine/threonine-protein kinase 1, SULFATE ION
Authors:Jauch, R, Wahl, M.C.
Deposit date:2006-08-01
Release date:2006-08-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.
Embo J., 25, 2006
1WXI
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BU of 1wxi by Molmil
E.coli NAD Synthetase, AMP.PP
Descriptor: ADENOSINE MONOPHOSPHATE, DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jauch, R, Humm, A, Huber, R, Wahl, M.C.
Deposit date:2005-01-23
Release date:2005-02-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements
J.Biol.Chem., 280, 2005
1WXG
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BU of 1wxg by Molmil
E.coli NAD Synthetase, DND
Descriptor: MAGNESIUM ION, NH(3)-dependent NAD(+) synthetase, NICOTINIC ACID ADENINE DINUCLEOTIDE
Authors:Jauch, R, Humm, A, Huber, R, Wahl, M.C.
Deposit date:2005-01-23
Release date:2005-02-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements
J.Biol.Chem., 280, 2005
1WXH
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BU of 1wxh by Molmil
E.coli NAD Synthetase, NAD
Descriptor: NH(3)-dependent NAD(+) synthetase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Jauch, R, Humm, A, Huber, R, Wahl, M.C.
Deposit date:2005-01-23
Release date:2005-02-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements
J.Biol.Chem., 280, 2005
1WXE
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BU of 1wxe by Molmil
E.coli NAD Synthetase, AMP
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, NH(3)-dependent NAD(+) synthetase
Authors:Jauch, R, Humm, A, Huber, R, Wahl, M.C.
Deposit date:2005-01-23
Release date:2005-02-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements
J.Biol.Chem., 280, 2005
1WXF
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BU of 1wxf by Molmil
E.coli NAD Synthetase
Descriptor: NH(3)-dependent NAD(+) synthetase
Authors:Jauch, R, Humm, A, Huber, R, Wahl, M.C.
Deposit date:2005-01-23
Release date:2005-02-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements
J.Biol.Chem., 280, 2005
4PFE
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BU of 4pfe by Molmil
Crystal structure of vsfGFP-0
Descriptor: Green fluorescent protein
Authors:Jauch, R, Chen, S.L.
Deposit date:2014-04-29
Release date:2015-06-24
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Rational Structure-Based Design of Bright GFP-Based Complexes with Tunable Dimerization.
Angew.Chem.Int.Ed.Engl., 54, 2015
5XGO
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BU of 5xgo by Molmil
The Ferritin E-Domain: Toward Understanding Its Role in Protein Cage Assembly Through the Crystal Structure of a Maxi-/Mini-Ferritin Chimera
Descriptor: CHLORIDE ION, DNA protection during starvation protein,Bacterioferritin
Authors:Cornell, T.A, Srivastava, Y, Jauch, R, Fan, R, Orner, B.P.
Deposit date:2017-04-14
Release date:2018-02-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The Crystal Structure of a Maxi/Mini-Ferritin Chimera Reveals Guiding Principles for the Assembly of Protein Cages.
Biochemistry, 56, 2017
7XRC
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BU of 7xrc by Molmil
Crystal Structure of the dimeric Brn2 (Pou3f2) POU domain bound to palindromic MORE DNA
Descriptor: More palindromic Oct factor Recognition Element (MORE), POU domain protein
Authors:Tan, D.S.Y, Jauch, R.
Deposit date:2022-05-10
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The homeodomain of Oct4 is a dimeric binder of methylated CpG elements.
Nucleic Acids Res., 51, 2023
4Y60
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BU of 4y60 by Molmil
Structure of SOX18-HMG/PROX1-DNA
Descriptor: DNA (5'-D(*CP*AP*CP*TP*AP*GP*CP*AP*TP*TP*GP*TP*CP*TP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*AP*GP*AP*CP*AP*AP*TP*GP*CP*TP*AP*GP*T)-3'), Transcription factor SOX-18
Authors:Narasimhan, K, Prokoph, N, Kolatkar, P, Robinson, H, Jauch, R.
Deposit date:2015-02-12
Release date:2016-03-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.
Nucleic Acids Res., 44, 2016
3F27
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BU of 3f27 by Molmil
Structure of Sox17 Bound to DNA
Descriptor: DNA (5'-D(*DCP*DCP*DAP*DGP*DGP*DAP*DCP*DAP*DAP*DTP*DAP*DGP*DAP*DGP*DAP*DC)-3'), DNA (5'-D(*DGP*DTP*DCP*DTP*DCP*DTP*DAP*DTP*DTP*DGP*DTP*DCP*DCP*DTP*DGP*DG)-3'), Transcription factor SOX-17
Authors:Palasingam, P, Jauch, R, Ng, C.K.L, Kolatkar, P.R.
Deposit date:2008-10-29
Release date:2009-04-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Structure of Sox17 Bound to DNA Reveals a Conserved Bending Topology but Selective Protein Interaction Platforms
J.Mol.Biol., 388, 2009
3QSV
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BU of 3qsv by Molmil
Structural basis for DNA recognition by constitutive Smad4 MH1 dimers
Descriptor: DNA (5'-D(P*TP*GP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 4, ZINC ION
Authors:Baburajendran, N, Jauch, R, Zhen, C.T.Y, Kolatkar, P.R.
Deposit date:2011-02-22
Release date:2011-06-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.708 Å)
Cite:Structural basis for DNA recognition by constitutive Smad4 MH1 dimers
To be Published
3KMP
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BU of 3kmp by Molmil
Crystal Structure of SMAD1-MH1/DNA complex
Descriptor: 5'-D(P*AP*TP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*AP*TP*A)-3', 5'-D(P*GP*TP*AP*TP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*A)-3', GLYCEROL, ...
Authors:Baburajendran, N, Palasingam, P, Narasimhan, K, Jauch, R, Kolatkar, P.R.
Deposit date:2009-11-11
Release date:2010-02-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors.
Nucleic Acids Res., 38, 2010
3L1P
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BU of 3l1p by Molmil
POU protein:DNA complex
Descriptor: DNA (5'-D(*AP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP*TP*CP*AP*AP*AP*TP*GP*TP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP*CP*AP*AP*AP*TP*GP*GP*A)-3'), POU domain, ...
Authors:Vahokoski, J, Groves, M.R, Pogenberg, V, Wilmanns, M.
Deposit date:2009-12-14
Release date:2010-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A unique Oct4 interface is crucial for reprogramming to pluripotency
Nat.Cell Biol., 15, 2013
4A3N
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BU of 4a3n by Molmil
Crystal Structure of HMG-BOX of Human SOX17
Descriptor: TRANSCRIPTION FACTOR SOX-17, ZINC ION
Authors:Gao, N, Gao, H, Qian, H, Si, S, Xie, Y.
Deposit date:2011-10-01
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Human Transcription Factor Sry-Related Box 17 Binding to DNA.
Protein Pept.Lett., 20, 2013

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数据于2024-11-06公开中

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