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1AN2
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BU of 1an2 by Molmil
RECOGNITION BY MAX OF ITS COGNATE DNA THROUGH A DIMERIC B/HLH/Z DOMAIN
Descriptor: DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*GP*AP*CP*C P*TP*AP*CP*AP*C)- 3'), PROTEIN (TRANSCRIPTION FACTOR MAX (TF MAX))
Authors:Ferre-D'Amare, A.R, Prendergast, G.C, Ziff, E.B, Burley, S.K.
Deposit date:1996-09-06
Release date:1997-09-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain.
Nature, 363, 1993
1AN4
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BU of 1an4 by Molmil
STRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF
Descriptor: DNA (5'-D(*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*C P*TP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*C P*GP*GP*GP*T)-3'), PROTEIN (UPSTREAM STIMULATORY FACTOR)
Authors:Ferre-D'Amare, A.R, Pognonec, P, Roeder, R.G, Burley, S.K.
Deposit date:1997-03-15
Release date:1997-09-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and function of the b/HLH/Z domain of USF.
EMBO J., 13, 1994
1DRZ
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BU of 1drz by Molmil
U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX
Descriptor: MAGNESIUM ION, PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), ...
Authors:Ferre-D'Amare, A.R, Zhou, K, Doudna, J.A.
Deposit date:1998-09-01
Release date:1999-02-16
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a hepatitis delta virus ribozyme.
Nature, 395, 1998
4TZY
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BU of 4tzy by Molmil
Vibrio vulnificus Adenine Riboswitch Variant, grown in both Sr2+ and Mg2+
Descriptor: ADENINE, MAGNESIUM ION, STRONTIUM ION, ...
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-11
Release date:2014-09-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZP
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BU of 4tzp by Molmil
As Grown, Untreated Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its cognate tRNAGly, and B. subtilis YbxF protein
Descriptor: Ribosome-associated protein L7Ae-like, engineered tRNA, glyQ T-box Stem I
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-10
Release date:2014-09-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (8.503 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZV
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BU of 4tzv by Molmil
Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate post crystallization
Descriptor: Ribosome-associated protein L7Ae-like, T-box stem I, engineered tRNA
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-11
Release date:2014-09-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (5.03 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
7MLW
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BU of 7mlw by Molmil
Burkholderia sp. TJI49 Guanidine-I riboswitch
Descriptor: GUANIDINE, Guanidine-I riboswitch, MAGNESIUM ION, ...
Authors:Trachman, R.J, Ferre-D'Amare, A.R.
Deposit date:2021-04-29
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An uncommon [K + (Mg 2+ ) 2 ] metal ion triad imparts stability and selectivity to the Guanidine-I riboswitch.
Rna, 27, 2021
2AQA
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BU of 2aqa by Molmil
NMR structural analysis of Nop10p from Saccharomyces cerevisiae
Descriptor: H/ACA ribonucleoprotein complex subunit 3
Authors:Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
Deposit date:2005-08-17
Release date:2005-11-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
2AQC
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BU of 2aqc by Molmil
NMR Structural analysis of archaeal Nop10
Descriptor: Ribosome biogenesis protein Nop10, ZINC ION
Authors:Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
Deposit date:2005-08-17
Release date:2005-11-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
4W90
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BU of 4w90 by Molmil
Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ...
Authors:Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.118 Å)
Cite:Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA.
Embo J., 33, 2014
4W92
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BU of 4w92 by Molmil
Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, 1,2-ETHANEDIOL, C-di-AMP ribsoswitch, ...
Authors:Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:2014-08-26
Release date:2014-10-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.209 Å)
Cite:Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA.
Embo J., 33, 2014
6WZS
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BU of 6wzs by Molmil
Fusibacterium ulcerans ZTP riboswitch bound to m-1-pyridinyl AICA
Descriptor: 5-amino-1-(pyridin-3-yl)-1H-imidazole-4-carboxamide, Fusibacterium ulcerans ZTP riboswitch, MAGNESIUM ION, ...
Authors:Pichling, P, Jones, C.P, Ferre-D'Amare, A.R, Tran, B.
Deposit date:2020-05-14
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design.
Cell Chem Biol, 27, 2020
6WZR
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BU of 6wzr by Molmil
Fusibacterium ulcerans ZTP riboswitch bound to p-1-pyridinyl AICA
Descriptor: 5-amino-1-(pyridin-4-yl)-1H-imidazole-4-carboxamide, Fusibacterium ulcerans ZTP riboswitch, MAGNESIUM ION, ...
Authors:Pichling, P, Jones, C.P, Ferre-D'Amare, A.R, Tran, B.
Deposit date:2020-05-14
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design.
Cell Chem Biol, 27, 2020
7SXP
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BU of 7sxp by Molmil
G-quadruplex structure formed in the NRAS mRNA with a G8U substitution
Descriptor: CACODYLIC ACID, NRAS mRNA, POTASSIUM ION
Authors:Banco, M.T, Ferre-D'Amare, A.R.
Deposit date:2021-11-24
Release date:2023-05-31
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Investigating the NRAS 5' UTR as a target for small molecules.
Cell Chem Biol, 30, 2023
1M5K
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BU of 1m5k by Molmil
Crystal structure of a hairpin ribozyme in the catalytically-active conformation
Descriptor: CALCIUM ION, CHLORIDE ION, PROTEIN (U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A), ...
Authors:Rupert, P.B, Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-08-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
1M5V
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BU of 1m5v by Molmil
Transition State Stabilization by a Catalytic RNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, RNA HAIRPIN RIBOZYME, ...
Authors:Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-10-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
1M5O
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BU of 1m5o by Molmil
Transition State Stabilization by a Catalytic RNA
Descriptor: CALCIUM ION, RNA SUBSTRATE, RNA HAIRPIN RIBOZYME, ...
Authors:Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-10-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
1M5P
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BU of 1m5p by Molmil
Transition State Stabilization by a Catalytic RNA
Descriptor: CALCIUM ION, RNA HAIRPIN RIBOZYME, RNA INHIBITOR SUBSTRATE, ...
Authors:Rupert, P.B, Massey, A, Sigurdsson, S.T, Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-10-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
4TZZ
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BU of 4tzz by Molmil
Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate and increasing PEG3350 concentration from 20% to 45% post crystallization
Descriptor: MAGNESIUM ION, Ribosome-associated protein L7Ae-like, T-box Stem I RNA, ...
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-11
Release date:2014-09-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZX
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BU of 4tzx by Molmil
Vibrio Vulnificus Adenine Riboswitch variant, grown in Mg2+
Descriptor: ADENINE, MAGNESIUM ION, Vibrio vulnificus Adenine Riboswitch
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-11
Release date:2014-09-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
1ZL3
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BU of 1zl3 by Molmil
Coupling of active site motions and RNA binding
Descriptor: 5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*UP*(FLO) UP*CP*GP*AP*UP*CP*CP*CP*GP*UP*UP*GP*C)-3', SULFATE ION, tRNA pseudouridine synthase B
Authors:Hoang, C, Hamilton, C.S, Mueller, E.G, Ferre-D'Amare, A.R.
Deposit date:2005-05-05
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain
Protein Sci., 14, 2005
2APO
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BU of 2apo by Molmil
Crystal Structure of the Methanococcus jannaschii Cbf5 Nop10 Complex
Descriptor: POTASSIUM ION, Probable tRNA pseudouridine synthase B, Ribosome biogenesis protein Nop10, ...
Authors:Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
Deposit date:2005-08-16
Release date:2005-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
1SB7
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BU of 1sb7 by Molmil
Crystal structure of the E.coli pseudouridine synthase TruD
Descriptor: GLYCEROL, PHOSPHATE ION, tRNA pseudouridine synthase D
Authors:Hoang, C, Ferre-D'Amare, A.R.
Deposit date:2004-02-10
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a conserved fold.
Rna, 10, 2004
3K1V
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BU of 3k1v by Molmil
Cocrystal structure of a mutant class-I preQ1 riboswitch
Descriptor: 7-DEAZA-7-AMINOMETHYL-GUANINE, CALCIUM ION, PreQ1 riboswitch
Authors:Klein, D.J, Edwards, T.E, Ferre-D'Amare, A.R.
Deposit date:2009-09-28
Release date:2009-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cocrystal Structure of a Class I Preq1 Riboswitch Reveals a Pseudoknot Recognizing an Essential Hypermodified Nucleobase
Nat.Struct.Mol.Biol., 16, 2009
3K0J
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BU of 3k0j by Molmil
Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module
Descriptor: MAGNESIUM ION, RNA (87-MER), THIAMINE DIPHOSPHATE, ...
Authors:Kulshina, N, Edwards, T.E, Ferre-D'Amare, A.R.
Deposit date:2009-09-24
Release date:2009-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch.
Rna, 16, 2010

223790

数据于2024-08-14公开中

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