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1U5U
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BU of 1u5u by Molmil
The structure of an Allene Oxide Synthase reveals a novel use for a catalase fold
Descriptor: Allene oxide synthase-lipoxygenase protein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Oldham, M.L, Brash, A.R, Newcomer, M.E.
Deposit date:2004-07-28
Release date:2005-01-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of coral allene oxide synthase reveals a catalase adapted for metabolism of a fatty acid hydroperoxide.
Proc.Natl.Acad.Sci.USA, 102, 2005
3O8Y
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BU of 3o8y by Molmil
Stable-5-Lipoxygenase
Descriptor: Arachidonate 5-lipoxygenase, FE (II) ION
Authors:Newcomer, M.E, Gilbert, N.C, Bartlett, S.G, Waight, M.T, Neau, D.B, Boeglin, W.E, Brash, A.R.
Deposit date:2010-08-03
Release date:2011-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.389 Å)
Cite:The structure of human 5-lipoxygenase.
Science, 331, 2011
2FNQ
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BU of 2fnq by Molmil
Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via A C2-like domain and a structural basis of product chirality
Descriptor: Allene oxide synthase-lipoxygenase protein, CALCIUM ION, FE (II) ION
Authors:Oldham, M.L, Brash, A.R, Newcomer, M.E.
Deposit date:2006-01-11
Release date:2006-02-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via a C2-like domain and a structural basis of product chirality.
J.Biol.Chem., 280, 2005
3V92
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BU of 3v92 by Molmil
S663A Stable-5-LOX
Descriptor: Arachidonate 5-lipoxygenase, FE (II) ION
Authors:Gilbert, N.C, Rui, Z, Neau, D.B, Waight, M, Bartlett, S.G, Boeglin, W.E, Brash, A.R, Newcomer, M.E.
Deposit date:2011-12-23
Release date:2012-05-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.
Faseb J., 26, 2012
3V98
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BU of 3v98 by Molmil
S663D Stable-5-LOX
Descriptor: Arachidonate 5-lipoxygenase, FE (II) ION
Authors:Gilbert, N.C, Rui, Z, Neau, D.B, Waight, M, Bartlett, S.G, Boeglin, W.E, Brash, A.R, Newcomer, M.E.
Deposit date:2011-12-23
Release date:2012-05-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.
Faseb J., 26, 2012
3V99
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BU of 3v99 by Molmil
S663D Stable-5-LOX in complex with Arachidonic Acid
Descriptor: ARACHIDONIC ACID, Arachidonate 5-lipoxygenase, FE (II) ION
Authors:Gilbert, N.C, Rui, Z, Neau, D.B, Waight, M, Bartlett, S.G, Boeglin, W.E, Brash, A.R, Newcomer, M.E.
Deposit date:2011-12-23
Release date:2012-05-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.252 Å)
Cite:Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.
Faseb J., 26, 2012
6NS5
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BU of 6ns5 by Molmil
Crystal structure of fungal lipoxygenase from Fusarium graminearum. Second C2 crystal form.
Descriptor: FE (II) ION, lipoxygenase
Authors:Pakhomova, S, Boeglin, W.E, Neau, D.B, Bartlett, S.G, Brash, A.R, Newcomer, M.E.
Deposit date:2019-01-24
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere.
Protein Sci., 28, 2019
6NS2
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BU of 6ns2 by Molmil
Crystal structure of fungal lipoxygenase from Fusarium graminearum. P212121 crystal form.
Descriptor: FE (II) ION, lipoxygenase
Authors:Pakhomova, S, Boeglin, W.E, Neau, D.B, Bartlett, S.G, Brash, A.R, Newcomer, M.E.
Deposit date:2019-01-24
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere.
Protein Sci., 28, 2019
6NS4
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BU of 6ns4 by Molmil
Crystal structure of fungal lipoxygenase from Fusarium graminearum. C2 crystal form.
Descriptor: ACETATE ION, FE (II) ION, GLYCEROL, ...
Authors:Pakhomova, S, Boeglin, W.E, Neau, D.B, Bartlett, S.G, Brash, A.R, Newcomer, M.E.
Deposit date:2019-01-24
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere.
Protein Sci., 28, 2019
6NS3
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BU of 6ns3 by Molmil
Crystal structure of fungal lipoxygenase from Fusarium graminearum. I222 crystal form.
Descriptor: FE (II) ION, lipoxygenase
Authors:Pakhomova, S, Boeglin, W.E, Neau, D.B, Bartlett, S.G, Brash, A.R, Newcomer, M.E.
Deposit date:2019-01-24
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere.
Protein Sci., 28, 2019
6NS6
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BU of 6ns6 by Molmil
Crystal structure of fungal lipoxygenase from Fusarium graminearum. P21 crystal form.
Descriptor: FE (II) ION, lipoxygenase
Authors:Pakhomova, S, Boeglin, W.E, Neau, D.B, Bartlett, S.G, Brash, A.R, Newcomer, M.E.
Deposit date:2019-01-24
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere.
Protein Sci., 28, 2019
4QWT
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BU of 4qwt by Molmil
Anaerobic crystal structure of delta413-417:GS LOX in complex with arachidonate
Descriptor: ACETATE ION, ARACHIDONIC ACID, Allene oxide synthase-lipoxygenase protein, ...
Authors:Neau, D.B, Newcomer, M.E.
Deposit date:2014-07-17
Release date:2014-09-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal Structure of a Lipoxygenase in Complex with Substrate: THE ARACHIDONIC ACID-BINDING SITE OF 8R-LIPOXYGENASE.
J.Biol.Chem., 289, 2014
3FG1
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BU of 3fg1 by Molmil
Crystal structure of Delta413-417:GS LOX
Descriptor: ACETIC ACID, Allene oxide synthase-lipoxygenase protein, CALCIUM ION, ...
Authors:Neau, D.B, Newcomer, M.E.
Deposit date:2008-12-04
Release date:2009-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity.
Biochemistry, 48, 2009
3DY5
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BU of 3dy5 by Molmil
Allene oxide synthase 8R-lipoxygenase from Plexaura homomalla
Descriptor: Allene oxide synthase-lipoxygenase protein, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Gilbert, N.C, Niebuhr, M, Tsuruta, H, Newcomer, M.E.
Deposit date:2008-07-25
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:A covalent linker allows for membrane targeting of an oxylipin biosynthetic complex.
Biochemistry, 47, 2008
3E4Y
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BU of 3e4y by Molmil
Crystal structure of a 33kDa catalase-related protein from Mycobacterium avium subsp. paratuberculosis. I2(1)2(1)2(1) crystal form
Descriptor: GLYCEROL, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Pakhomova, S, Newcomer, M.E.
Deposit date:2008-08-12
Release date:2009-08-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure and peroxidase activity of a 33-kDa catalase-related protein from Mycobacterium avium ssp. paratuberculosis.
Protein Sci., 18, 2009
3FG3
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BU of 3fg3 by Molmil
Crystal structure of Delta413-417:GS I805W LOX
Descriptor: ACETIC ACID, Allene oxide synthase-lipoxygenase protein, CALCIUM ION, ...
Authors:Neau, D.B, Newcomer, M.E.
Deposit date:2008-12-04
Release date:2009-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity.
Biochemistry, 48, 2009
3E4W
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BU of 3e4w by Molmil
Crystal structure of a 33kDa catalase-related protein from Mycobacterium avium subsp. paratuberculosis. P2(1)2(1)2(1) crystal form.
Descriptor: GLYCEROL, HEXANE-1,6-DIOL, PHOSPHATE ION, ...
Authors:Pakhomova, S, Newcomer, M.E.
Deposit date:2008-08-12
Release date:2009-08-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure and peroxidase activity of a 33-kDa catalase-related protein from Mycobacterium avium ssp. paratuberculosis.
Protein Sci., 18, 2009
3FG4
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BU of 3fg4 by Molmil
Crystal structure of Delta413-417:GS I805A LOX
Descriptor: ACETIC ACID, ARACHIDONIC ACID, Allene oxide synthase-lipoxygenase protein, ...
Authors:Neau, D.B, Newcomer, M.E.
Deposit date:2008-12-04
Release date:2009-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity.
Biochemistry, 48, 2009

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数据于2024-11-06公开中

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