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4RWF
Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin
Descriptor:
1,2-ETHANEDIOL, Adrenomedullin, Maltose transporter subunit, ...
Authors:
Booe, J
,
Pioszak, A.
Deposit date:
2014-12-03
Release date:
2015-05-20
Last modified:
2020-07-29
Method:
X-RAY DIFFRACTION (1.76 Å)
Cite:
Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.
Mol.Cell, 58, 2015
4RWG
Crystal structure of the CLR:RAMP1 extracellular domain heterodimer with bound high affinity CGRP analog
Descriptor:
CGRP analog, MAGNESIUM ION, Maltose-binding periplasmic protein, ...
Authors:
Booe, J
,
Pioszak, A.
Deposit date:
2014-12-03
Release date:
2015-05-20
Last modified:
2023-09-20
Method:
X-RAY DIFFRACTION (2.44 Å)
Cite:
Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.
Mol.Cell, 58, 2015
5V6Y
Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity and altered selectivity adrenomedullin variant
Descriptor:
ADM, Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:
Pioszak, A
,
Booe, J.
Deposit date:
2017-03-17
Release date:
2018-01-31
Last modified:
2023-10-04
Method:
X-RAY DIFFRACTION (2.8 Å)
Cite:
Probing the Mechanism of Receptor Activity-Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists.
Mol. Pharmacol., 93, 2018
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数据于2024-10-09公开中