2FOK
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2GIG
| Alteration of sequence specificity of the type II restriction endonuclease HINCII through an indirect readout mechanism | Descriptor: | 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*GP*C)-3', SODIUM ION, Type II restriction enzyme HincII | Authors: | Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J. | Deposit date: | 2006-03-28 | Release date: | 2006-07-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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2GIE
| HincII bound to cognate DNA GTTAAC | Descriptor: | 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*G)-3', SODIUM ION, Type II restriction enzyme HincII | Authors: | Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J. | Deposit date: | 2006-03-28 | Release date: | 2006-07-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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2GIH
| Q138F HincII bound to cognate DNA GTCGAC and Ca2+ | Descriptor: | 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, Type II restriction enzyme HincII | Authors: | Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J. | Deposit date: | 2006-03-28 | Release date: | 2006-07-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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3MQY
| SgrAI with cleaved DNA and Magnesium bound | Descriptor: | DNA (5'-D(*GP*AP*GP*TP*CP*CP*A)-3'), DNA (5'-D(P*CP*CP*GP*GP*TP*GP*GP*AP*CP*TP*C)-3'), MAGNESIUM ION, ... | Authors: | Dunten, P.W, Horton, N.C, Little, E.J. | Deposit date: | 2010-04-28 | Release date: | 2010-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA. Acta Crystallogr.,Sect.D, 67, 2011
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3N7B
| SgrAI bound to secondary site DNA and Ca(II) | Descriptor: | CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*AP*CP*CP*GP*GP*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*CP*CP*CP*CP*CP*GP*GP*TP*GP*GP*AP*CP*T)-3'), ... | Authors: | Horton, N.C, Little, E.J, Dunten, P.W. | Deposit date: | 2010-05-26 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA. Acta Crystallogr.,Sect.D, 67, 2011
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3N78
| SgrAI bound to Secondary Site DNA and Mg(II) | Descriptor: | DNA (5'-D(*AP*GP*TP*CP*CP*AP*CP*CP*GP*GP*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*CP*CP*CP*CP*CP*GP*GP*TP*GP*GP*AP*CP*T)-3'), MAGNESIUM ION, ... | Authors: | Horton, N.C, Little, E.J, Dunten, P.W. | Deposit date: | 2010-05-26 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA. Acta Crystallogr.,Sect.D, 67, 2011
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3MQ6
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2GIJ
| Q138F HincII bound to cognate DNA GTTAAC and Ca2+ | Descriptor: | 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, SODIUM ION, ... | Authors: | Horton, N.C, Joshi, H.K. | Deposit date: | 2006-03-28 | Release date: | 2006-07-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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2GII
| Q138F HincII bound to cognate DNA GTTAAC | Descriptor: | 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*GP*C)-3', Type II restriction enzyme HincII | Authors: | Horton, N.C, Joshi, H.K. | Deposit date: | 2006-03-28 | Release date: | 2006-07-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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3E44
| Q138F HincII bound to cleaved DNA (GTT | AAC) and Mn2+ | Descriptor: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DT)-3', 5'-D(P*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', MANGANESE (II) ION, ... | Authors: | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | Deposit date: | 2008-08-08 | Release date: | 2008-08-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E42
| Q138F HincII bound to GTCGAC and Ca2+ (cocrystallized) | Descriptor: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ... | Authors: | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | Deposit date: | 2008-08-08 | Release date: | 2008-08-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E40
| Q138F HincII bound to GTTAAC and cocrystallized with 5 mM Ca2+ | Descriptor: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3'), CALCIUM ION, SODIUM ION, ... | Authors: | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | Deposit date: | 2008-08-08 | Release date: | 2008-08-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E3Y
| Q138F HincII bound to GTTAAC and cocrystallized with 5 mM Ca2+ | Descriptor: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DTP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ... | Authors: | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | Deposit date: | 2008-08-08 | Release date: | 2008-08-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3E43
| Q138F HincII bound to GTTAAC and cocrystallized with 2.5 mM MgCl2 | Descriptor: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DTP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', Type-2 restriction enzyme HindII, UNKNOWN ATOM OR ION | Authors: | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | Deposit date: | 2008-08-08 | Release date: | 2008-08-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3DVO
| SgrAI with cognate DNA and calcium bound | Descriptor: | CALCIUM ION, DNA (5'-D(*DGP*DAP*DGP*DTP*DCP*DCP*DAP*DCP*DCP*DGP*DGP*DTP*DGP*DGP*DAP*DCP*DTP*DC)-3'), SgraIR restriction enzyme | Authors: | Dunten, P.W, Horton, N.C, Little, E.J. | Deposit date: | 2008-07-18 | Release date: | 2008-08-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.892 Å) | Cite: | The structure of SgrAI bound to DNA; recognition of an 8 base pair target. Nucleic Acids Res., 36, 2008
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3E45
| Q138F HincII bound to Noncognate DNA (GTGCAC) and Ca2+ | Descriptor: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DGP*DCP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ... | Authors: | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | Deposit date: | 2008-08-08 | Release date: | 2008-08-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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3DPG
| SgrAI with noncognate DNA bound | Descriptor: | CALCIUM ION, DNA (5'-D(*DAP*DAP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DTP*DGP*DGP*DAP*DCP*DT)-3'), SgraIR restriction enzyme | Authors: | Dunten, P.W, Horton, N.C, Little, E.J. | Deposit date: | 2008-07-08 | Release date: | 2008-08-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | The structure of SgrAI bound to DNA; recognition of an 8 base pair target. Nucleic Acids Res., 36, 2008
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3DW9
| SgrAI with cognate DNA and manganese bound | Descriptor: | DNA (5'-D(*DGP*DAP*DGP*DTP*DCP*DCP*DAP*DCP*DCP*DGP*DGP*DTP*DGP*DGP*DAP*DCP*DTP*DC)-3'), MANGANESE (II) ION, SgraIR restriction enzyme | Authors: | Dunten, P.W, Horton, N.C, Little, E.J. | Deposit date: | 2008-07-21 | Release date: | 2008-08-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of SgrAI bound to DNA; recognition of an 8 base pair target. Nucleic Acids Res., 36, 2008
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3E41
| Q138F HincII bound to GTCGAC and 5 mM Ca2+ | Descriptor: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ... | Authors: | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | Deposit date: | 2008-08-08 | Release date: | 2008-08-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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