3CMY
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![BU of 3cmy by Molmil](/molmil-images/mine/3cmy) | Structure of a homeodomain in complex with DNA | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*DAP*DCP*DAP*DTP*DAP*DAP*DP*DCP*DGP*DAP*DTP*DTP*DAP*DC)-3', 5'-D(*DTP*DGP*DTP*DAP*DAP*DTP*DCP*DGP*DAP*DTP*DTP*DAP*DTP*DG)-3', ... | Authors: | Birrane, G, Ladias, J.A.A, Soni, A. | Deposit date: | 2008-03-24 | Release date: | 2009-02-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Basis for DNA Recognition by the Human PAX3 Homeodomain. Biochemistry, 48, 2009
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1MFG
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![BU of 1mfg by Molmil](/molmil-images/mine/1mfg) | |
1MFL
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![BU of 1mfl by Molmil](/molmil-images/mine/1mfl) | |
4XWH
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![BU of 4xwh by Molmil](/molmil-images/mine/4xwh) | Crystal structure of the human N-acetyl-alpha-glucosaminidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylglucosaminidase, ... | Authors: | Birrane, G, Meiyappan, M, Dassier, A. | Deposit date: | 2015-01-28 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural characterization of the alpha-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B. J.Struct.Biol., 205, 2019
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3BYA
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![BU of 3bya by Molmil](/molmil-images/mine/3bya) | |
4R2Z
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![BU of 4r2z by Molmil](/molmil-images/mine/4r2z) | |
4LG0
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![BU of 4lg0 by Molmil](/molmil-images/mine/4lg0) | Structure of a ternary FOXO1-ETS1 DNA complex | Descriptor: | CALCIUM ION, DNA (5'-D(*DAP*DAP*DAP*DCP*DAP*DAP*DTP*DAP*DAP*DCP*DAP*DGP*DGP*DAP*DAP*DAP*DCP*DCP*DGP*DTP*DG)-3'), DNA (5'-D(*DTP*DTP*DCP*DAP*DCP*DGP*DGP*DTP*DTP*DTP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DTP*DGP*DT)-3'), ... | Authors: | Birrane, G, Choy, W.C, Datta, D, Geiger, C.A, Grant, M.A. | Deposit date: | 2013-06-27 | Release date: | 2014-07-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structure of a ternary FOXO1-ETS1 DNA complex To be Published
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6E7K
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![BU of 6e7k by Molmil](/molmil-images/mine/6e7k) | |
2NTE
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![BU of 2nte by Molmil](/molmil-images/mine/2nte) | Crystal Structure of the BARD1 BRCT Domains | Descriptor: | 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ... | Authors: | Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A. | Deposit date: | 2006-11-07 | Release date: | 2007-06-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the BARD1 BRCT domains. Biochemistry, 46, 2007
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3QH5
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![BU of 3qh5 by Molmil](/molmil-images/mine/3qh5) | Structure of Thermolysin in complex with N-Carbobenzyloxy-L-aspartic acid and L-Phenylalanine Methyl Ester | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, N-[(benzyloxy)carbonyl]-L-aspartic acid, ... | Authors: | Birrane, G, Bhyravbhatla, B, Navia, M. | Deposit date: | 2011-01-25 | Release date: | 2012-01-04 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Synthesis of Aspartame by Thermolysin: An X-ray Structural Study. ACS MED.CHEM.LETT., 5, 2014
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3QGO
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![BU of 3qgo by Molmil](/molmil-images/mine/3qgo) | Structure of Thermolysin in complex with L-Phenylalanine methylester | Descriptor: | ACETATE ION, CALCIUM ION, DIMETHYL SULFOXIDE, ... | Authors: | Birrane, G, Bhyravbhatla, B, Navia, M. | Deposit date: | 2011-01-24 | Release date: | 2012-01-04 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Synthesis of Aspartame by Thermolysin: An X-ray Structural Study. ACS MED.CHEM.LETT., 5, 2014
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3QH1
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![BU of 3qh1 by Molmil](/molmil-images/mine/3qh1) | Structure of Thermolysin in complex with N-benzyloxycarbonyl-L-aspartic acid | Descriptor: | CALCIUM ION, N-[(benzyloxy)carbonyl]-L-aspartic acid, Thermolysin, ... | Authors: | Birrane, G, Bhyravbhatla, B, Navia, M. | Deposit date: | 2011-01-25 | Release date: | 2012-01-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Synthesis of Aspartame by Thermolysin: An X-ray Structural Study. ACS MED.CHEM.LETT., 5, 2014
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4F8K
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![BU of 4f8k by Molmil](/molmil-images/mine/4f8k) | Molecular analysis of the interaction between the prostacyclin receptor and the first PDZ domain of PDZK1 | Descriptor: | Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Prostacyclin receptor | Authors: | Kocher, O, Birrane, G, Kinsella, B.T, Mulvaney, E.P. | Deposit date: | 2012-05-17 | Release date: | 2013-02-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular Analysis of the Prostacyclin Receptor's Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1. Plos One, 8, 2013
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6XIY
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![BU of 6xiy by Molmil](/molmil-images/mine/6xiy) | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to methyl 2-(acetylamino)-2-deoxy-1-thio-alpha-D-galactopyranose | Descriptor: | C-type lectin domain family 10 member A, CALCIUM ION, CHLORIDE ION, ... | Authors: | Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G. | Deposit date: | 2020-06-22 | Release date: | 2021-03-31 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.307 Å) | Cite: | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen. Biochemistry, 60, 2021
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6OA6
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![BU of 6oa6 by Molmil](/molmil-images/mine/6oa6) | |
6PY1
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![BU of 6py1 by Molmil](/molmil-images/mine/6py1) | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, ACETATE ION, C-type lectin domain family 10 member A, ... | Authors: | Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G. | Deposit date: | 2019-07-28 | Release date: | 2020-07-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen. Biochemistry, 60, 2021
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6PUV
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![BU of 6puv by Molmil](/molmil-images/mine/6puv) | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin | Descriptor: | C-type lectin domain family 10 member A, CALCIUM ION | Authors: | Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G. | Deposit date: | 2019-07-18 | Release date: | 2020-07-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen. Biochemistry, 60, 2021
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6N63
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![BU of 6n63 by Molmil](/molmil-images/mine/6n63) | Crystal structure of an Iron binding protein | Descriptor: | ACETATE ION, ENCAPSULIN CARGO PROTEIN, FE (III) ION, ... | Authors: | Birrane, G, Geissen, T.W. | Deposit date: | 2018-11-24 | Release date: | 2019-07-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Large protein organelles form a new iron sequestration system with high storage capacity. Elife, 8, 2019
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6W12
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![BU of 6w12 by Molmil](/molmil-images/mine/6w12) | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to the Tumor-Associated Tn Antigen | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, C-type lectin domain family 10 member A, CALCIUM ION, ... | Authors: | Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G. | Deposit date: | 2020-03-03 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen. Biochemistry, 60, 2021
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6O31
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2ING
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![BU of 2ing by Molmil](/molmil-images/mine/2ing) | X-ray Structure of the BRCA1 BRCT mutant M1775K | Descriptor: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION | Authors: | Birrane, G, Soni, A, Ladias, J.A.A. | Deposit date: | 2006-10-07 | Release date: | 2007-09-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach. Eur.J.Hum.Genet., 16, 2008
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1Q9H
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![BU of 1q9h by Molmil](/molmil-images/mine/1q9h) | 3-Dimensional structure of native Cel7A from Talaromyces emersonii | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, cellobiohydrolase I catalytic domain | Authors: | Grassick, A, Thompson, R, Murray, P.G, Collins, C.M, Byrnes, L, Tuohy, M.G, Birrane, G, Higgins, T.M. | Deposit date: | 2003-08-25 | Release date: | 2004-11-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii Eur.J.Biochem., 271, 2004
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5D8J
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![BU of 5d8j by Molmil](/molmil-images/mine/5d8j) | |
1Y98
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![BU of 1y98 by Molmil](/molmil-images/mine/1y98) | Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide. | Descriptor: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ... | Authors: | Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A. | Deposit date: | 2004-12-14 | Release date: | 2005-08-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex. Biochemistry, 44, 2005
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3NGH
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![BU of 3ngh by Molmil](/molmil-images/mine/3ngh) | Molecular Analysis of the Interaction of the HDL Receptor SR-BI with the Adaptor Protein PDZK1 | Descriptor: | PDZ domain-containing protein 1 | Authors: | Kocher, O, Birrane, G, Krieger, M, Ladias, J.A. | Deposit date: | 2010-06-11 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1. J.Biol.Chem., 285, 2010
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