8U4C
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![BU of 8u4c by Molmil](/molmil-images/mine/8u4c) | Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation. | Descriptor: | Insulin receptor, Insulin-like growth factor II | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2023-09-10 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8VJC
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![BU of 8vjc by Molmil](/molmil-images/mine/8vjc) | Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation. | Descriptor: | Insulin-like growth factor II, Isoform Short of Insulin receptor | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2024-01-06 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8U4E
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![BU of 8u4e by Molmil](/molmil-images/mine/8u4e) | Cryo-EM structure of long form insulin receptor (IR-B) with three IGF2 bound, asymmetric conformation. | Descriptor: | Insulin receptor, Insulin-like growth factor II | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2023-09-10 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8VJB
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![BU of 8vjb by Molmil](/molmil-images/mine/8vjb) | Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation. | Descriptor: | Insulin-like growth factor II, Isoform Short of Insulin receptor | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2024-01-06 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8U4B
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![BU of 8u4b by Molmil](/molmil-images/mine/8u4b) | Cryo-EM structure of long form insulin receptor (IR-B) in the apo state | Descriptor: | Insulin receptor | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2023-09-10 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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5YZ4
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![BU of 5yz4 by Molmil](/molmil-images/mine/5yz4) | Structure of the PIN domain endonuclease Utp24 | Descriptor: | CALCIUM ION, ZINC ION, rRNA-processing protein fcf1 | Authors: | Du, Y, An, W, Ye, K. | Deposit date: | 2017-12-12 | Release date: | 2018-12-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.135 Å) | Cite: | Structural and functional analysis of Utp24, an endonuclease for processing 18S ribosomal RNA. Plos One, 13, 2018
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7U5V
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![BU of 7u5v by Molmil](/molmil-images/mine/7u5v) | Crystal structure of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and Borealin peptide | Descriptor: | Borealin, Histone-lysine N-methyltransferase 2A, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | An, S, Cho, U.S, Oh, H, Sha, L, Xu, J, Kim, S, Yang, W, An, W, Dou, Y. | Deposit date: | 2022-03-02 | Release date: | 2023-09-27 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Non-canonical MLL1 activity regulates centromeric phase separation and genome stability. Nat.Cell Biol., 25, 2023
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7KN0
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![BU of 7kn0 by Molmil](/molmil-images/mine/7kn0) | Structure of the integrin aIIb(W968V)b3 transmembrane complex | Descriptor: | Integrin alpha-IIb, Integrin beta-3 | Authors: | Situ, A.J, Kim, J, An, W, Kim, C, Ulmer, T.S. | Deposit date: | 2020-11-03 | Release date: | 2021-09-15 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Insight Into Pathological Integrin alpha IIb beta 3 Activation From Safeguarding The Inactive State. J.Mol.Biol., 433, 2021
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2NA8
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![BU of 2na8 by Molmil](/molmil-images/mine/2na8) | Transmembrane Structure of the Cytokine Receptor Common Subunit beta | Descriptor: | Cytokine receptor common subunit beta | Authors: | Schmidt, T, Ye, F, Situ, A.J, An, W, Ginsberg, M.H, Ulmer, T.S. | Deposit date: | 2015-12-21 | Release date: | 2016-07-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors. J.Biol.Chem., 291, 2016
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2NA9
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![BU of 2na9 by Molmil](/molmil-images/mine/2na9) | Transmembrane Structure of the P441A Mutant of the Cytokine Receptor Common Subunit beta | Descriptor: | Cytokine receptor common subunit beta | Authors: | Schmidt, T, Ye, F, Situ, A.J, An, W, Ginsberg, M.H, Ulmer, T.S. | Deposit date: | 2015-12-21 | Release date: | 2016-07-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors. J.Biol.Chem., 291, 2016
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6KE6
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![BU of 6ke6 by Molmil](/molmil-images/mine/6ke6) | |
6LQS
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![BU of 6lqs by Molmil](/molmil-images/mine/6lqs) | |
6LQR
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![BU of 6lqr by Molmil](/molmil-images/mine/6lqr) | |
6LQV
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![BU of 6lqv by Molmil](/molmil-images/mine/6lqv) | |
6LQT
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![BU of 6lqt by Molmil](/molmil-images/mine/6lqt) | |
6LQQ
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![BU of 6lqq by Molmil](/molmil-images/mine/6lqq) | |
6LQP
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![BU of 6lqp by Molmil](/molmil-images/mine/6lqp) | |
7D4I
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![BU of 7d4i by Molmil](/molmil-images/mine/7d4i) | Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-24 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1 To Be Published
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7D63
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![BU of 7d63 by Molmil](/molmil-images/mine/7d63) | Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-29 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (12.3 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) To Be Published
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7D5S
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![BU of 7d5s by Molmil](/molmil-images/mine/7d5s) | Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S12, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-28 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) To Be Published
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7D5T
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![BU of 7d5t by Molmil](/molmil-images/mine/7d5t) | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-28 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) To Be Published
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6LQU
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5WWO
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![BU of 5wwo by Molmil](/molmil-images/mine/5wwo) | Crystal structure of Enp1 | Descriptor: | Essential nuclear protein 1, Protein LTV1 | Authors: | Ye, K, Zhang, W. | Deposit date: | 2017-01-03 | Release date: | 2017-06-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular architecture of the 90S small subunit pre-ribosome Elife, 6, 2017
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5WWN
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![BU of 5wwn by Molmil](/molmil-images/mine/5wwn) | Crystal structure of Tsr1 | Descriptor: | Ribosome biogenesis protein TSR1, SULFATE ION | Authors: | Ye, K, Wang, B. | Deposit date: | 2017-01-03 | Release date: | 2017-06-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | Molecular architecture of the 90S small subunit pre-ribosome Elife, 6, 2017
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5WXM
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![BU of 5wxm by Molmil](/molmil-images/mine/5wxm) | Crystal structure of the Imp3 and Mpp10 complex | Descriptor: | SULFATE ION, U3 small nucleolar RNA-associated protein MPP10, U3 small nucleolar ribonucleoprotein protein IMP3 | Authors: | Ye, K, Zheng, S. | Deposit date: | 2017-01-07 | Release date: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Molecular architecture of the 90S small subunit pre-ribosome Elife, 6, 2017
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