3RE6
 
 | | Crystal structure of R4-6 streptavidin | | Descriptor: | GLYCEROL, Streptavidin | | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | | Deposit date: | 2011-04-02 | | Release date: | 2011-07-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.823 Å) | | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding.
Protein Sci., 20, 2011
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3RDQ
 | | Crystal structure of R7-2 streptavidin complexed with desthiobiotin | | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, GLYCEROL, NICKEL (II) ION, ... | | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | | Deposit date: | 2011-04-01 | | Release date: | 2011-07-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding.
Protein Sci., 20, 2011
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3KCS
 | | Crystal structure of PAmCherry1 in the dark state | | Descriptor: | PAmCherry1 protein | | Authors: | Malashkevich, V.N, Subach, F.V, Zencheck, W.D, Xiao, H, Filonov, G.S, Almo, S.C, Verkhusha, V.V. | | Deposit date: | 2009-10-21 | | Release date: | 2009-11-17 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Photoactivation mechanism of PAmCherry based on crystal structures of the protein in the dark and fluorescent states.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3KCT
 | | CRYSTAL STRUCTURE OF PAmCherry1 in the photoactivated state | | Descriptor: | PAmCherry1 protein | | Authors: | Malashkevich, V.N, Subach, F.V, Zencheck, W.D, Xiao, H, Filonov, G.S, Almo, S.C, Verkhusha, V.V. | | Deposit date: | 2009-10-21 | | Release date: | 2009-11-17 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Photoactivation mechanism of PAmCherry based on crystal structures of the protein in the dark and fluorescent states.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2OZT
 | | Crystal structure of O-succinylbenzoate synthase from Thermosynechococcus elongatus BP-1 | | Descriptor: | PHOSPHATE ION, SODIUM ION, Tlr1174 protein | | Authors: | Malashkevich, V.N, Bonanno, J, Toro, R, Sauder, J.M, Schwinn, K.D, Bain, K.T, Adams, J.M, Reyes, C, Rooney, I, Gheyi, T, Wasserman, S.R, Emtage, S, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2007-02-27 | | Release date: | 2007-03-13 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2Q6Q
 | | Crystal structure of Spc42p, a critical component of spindle pole body in budding yeast | | Descriptor: | CHLORIDE ION, COBALT (II) ION, Spindle pole body component SPC42 | | Authors: | Malashkevich, V.N, Newman, J.R, Kim, P.S. | | Deposit date: | 2007-06-05 | | Release date: | 2008-05-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Analysis of coiled-coil interactions between core proteins of the spindle pole body.
Biochemistry, 47, 2008
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1ARG
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1ARI
 | | Aspartate aminotransferase, W140H mutant, maleate complex | | Descriptor: | ASPARTATE AMINOTRANSFERASE, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Malashkevich, V.N, Jansonius, J.N. | | Deposit date: | 1995-08-23 | | Release date: | 1995-11-14 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Substitution of apolar residues in the active site of aspartate aminotransferase by histidine. Effects on reaction and substrate specificity.
Eur.J.Biochem., 227, 1995
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1ARH
 | | ASPARTATE AMINOTRANSFERASE, Y225R/R386A MUTANT | | Descriptor: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYLENE)-AMINO]-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE | | Authors: | Malashkevich, V.N, Jansonius, J.N. | | Deposit date: | 1995-08-23 | | Release date: | 1995-11-14 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme.
Eur.J.Biochem., 232, 1995
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1BQD
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3FON
 | | Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFEAI | | Descriptor: | Beta-2-microglobulin, MHC, Peptide | | Authors: | Malashkevich, V.N, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Brims, D.R, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P. | | Deposit date: | 2008-12-30 | | Release date: | 2010-01-12 | | Last modified: | 2020-02-05 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
Int.Immunol., 22, 2010
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1BQA
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3M24
 | | Crystal structure of TagBFP fluorescent protein | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, GLYCEROL, ... | | Authors: | Malashkevich, V.N, Subach, O.M, Almo, S.C, Verkhusha, V.V. | | Deposit date: | 2010-03-06 | | Release date: | 2010-05-26 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural characterization of acylimine-containing blue and red chromophores in mTagBFP and TagRFP fluorescent proteins.
Chem.Biol., 17, 2010
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3NT3
 | | CRYSTAL STRUCTURE OF LSSmKate2 red fluorescent proteins with large Stokes shift | | Descriptor: | GLYCEROL, LSSmKate2 red fluorescent protein | | Authors: | Malashkevich, V.N, Piatkevich, K, Almo, S.C, Verkhusha, V. | | Deposit date: | 2010-07-02 | | Release date: | 2010-08-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Engineering ESPT Pathways Based on Structural Analysis of LSSmKate Red Fluorescent Proteins with Large Stokes Shift.
J.Am.Chem.Soc., 132, 2010
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3M22
 | | Crystal structure of TagRFP fluorescent protein | | Descriptor: | TagRFP | | Authors: | Malashkevich, V.N, Subach, O.M, Ramagopal, U.A, Almo, S.C, Verkhusha, V.V. | | Deposit date: | 2010-03-06 | | Release date: | 2010-05-12 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural characterization of acylimine-containing blue and red chromophores in mTagBFP and TagRFP fluorescent proteins.
Chem.Biol., 17, 2010
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3NT9
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4KGF
 | | Crystal structure of near-infrared fluorescent protein with an extended stokes shift, ph 8.0 | | Descriptor: | CHLORIDE ION, TagRFP675, red fluorescent protein | | Authors: | Malashkevich, V.N, Piatkevich, K, Almo, S.C, Verkhusha, V, New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2013-04-29 | | Release date: | 2013-05-08 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Extended Stokes shift in fluorescent proteins: chromophore-protein interactions in a near-infrared TagRFP675 variant.
Sci Rep, 3, 2013
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4KGE
 | | Crystal structure of near-infrared fluorescent protein with an extended stokes shift, pH 4.5 | | Descriptor: | CHLORIDE ION, TagRFP675, red fluorescent protein | | Authors: | Malashkevich, V.N, Piatkevich, K, Almo, S.C, Verkhusha, V, New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2013-04-29 | | Release date: | 2013-05-08 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Extended Stokes shift in fluorescent proteins: chromophore-protein interactions in a near-infrared TagRFP675 variant.
Sci Rep, 3, 2013
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4N23
 | | Crystal structure of the GP2 Core Domain from the California Academy of Science Virus, monoclinic symmetry | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, GP2 Ectodomain | | Authors: | Malashkevich, V.N, Koellhoffer, J.F, Dai, Z, Toro, R, Lai, J.R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2013-10-04 | | Release date: | 2013-11-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species.
J.Mol.Biol., 426, 2014
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1FBM
 | | ASSEMBLY DOMAIN OF CARTILAGE OLIGOMERIC MATRIX PROTEIN IN COMPLEX WITH ALL-TRANS RETINOL | | Descriptor: | PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN), RETINOL | | Authors: | Guo, Y, Bozic, D, Malashkevich, V.N, Kammerer, R.A, Schulthess, T. | | Deposit date: | 2000-07-16 | | Release date: | 2000-08-02 | | Last modified: | 2018-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | All-trans retinol, vitamin D and other hydrophobic compounds bind in the axial pore of the five-stranded coiled-coil domain of cartilage oligomeric matrix protein.
EMBO J., 17, 1998
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1PIQ
 | | CRYSTAL STRUCTURE OF GCN4-PIQ, A TRIMERIC COILED COIL WITH BURIED POLAR RESIDUES | | Descriptor: | CHLORIDE ION, PROTEIN (GENERAL CONTROL PROTEIN GCN4-PIQ) | | Authors: | Eckert, D.M, Malashkevich, V.N, Kim, P.S. | | Deposit date: | 1998-09-25 | | Release date: | 1998-09-30 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of GCN4-pIQI, a trimeric coiled coil with buried polar residues.
J.Mol.Biol., 284, 1998
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4XTQ
 | | Crystal structure of a mutant (C20S) of a near-infrared fluorescent protein BphP1-FP | | Descriptor: | 3-[2-[(Z)-[5-[(Z)-[(3R,4R)-3-ethenyl-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, BphP1-FP/C20S, CHLORIDE ION | | Authors: | Pletnev, S, Malashkevich, V.N. | | Deposit date: | 2015-01-23 | | Release date: | 2015-12-09 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Molecular Basis of Spectral Diversity in Near-Infrared Phytochrome-Based Fluorescent Proteins.
Chem.Biol., 22, 2015
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1G2C
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1JS6
 | | Crystal Structure of DOPA decarboxylase | | Descriptor: | DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Burkhard, P, Dominici, P, Borri-Voltattorni, C, Jansonius, J.N, Malashkevich, V.N. | | Deposit date: | 2001-08-16 | | Release date: | 2001-10-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase.
Nat.Struct.Biol., 8, 2001
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1JS3
 | | Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa | | Descriptor: | CARBIDOPA, DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Burkhard, P, Dominici, P, Borri-Voltattorni, C, Jansonius, J.N, Malashkevich, V.N. | | Deposit date: | 2001-08-16 | | Release date: | 2001-10-26 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase.
Nat.Struct.Biol., 8, 2001
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