7TVI
| Alpha1/BetaB Heteromeric Glycine Receptor in Glycine-Bound State | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, Glycine receptor beta subunit 2, ... | Authors: | Gibbs, E, Chakrapani, S, Kumar, A. | Deposit date: | 2022-02-04 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Conformational transitions and allosteric modulation in a heteromeric glycine receptor Nat Commun, 14, 2023
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2BPG
| STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP | Descriptor: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*GP*CP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*G)-3'), ... | Authors: | Pelletier, H, Sawaya, M.R, Kumar, A, Wilson, S.H, Kraut, J. | Deposit date: | 1994-05-19 | Release date: | 1994-08-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science, 264, 1994
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8OUI
| Complex of ASCT2 with Suppressyn | Descriptor: | ALANINE, Neutral amino acid transporter B(0), Suppressyn | Authors: | Khare, S, Kumar, A, Reyes, N. | Deposit date: | 2023-04-23 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins. Nat.Struct.Mol.Biol., 2024
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4YN6
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6I1D
| Structure of the Ysh1-Mpe1 nuclease complex from S.cerevisiae | Descriptor: | Endoribonuclease YSH1, GLYCEROL, Protein MPE1, ... | Authors: | Hill, C.H, Boreikaite, V, Kumar, A, Casanal, A, Kubik, P, Degliesposti, G, Maslen, S, Mariani, A, von Loeffelholz, O, Girbig, M, Skehel, M, Passmore, L.A. | Deposit date: | 2018-10-28 | Release date: | 2019-02-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex. Mol.Cell, 73, 2019
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3QG1
| Crystal structure of P-loop G239A mutant of subunit A of the A1AO ATP synthase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, V-type ATP synthase alpha chain | Authors: | Ragunathan, P, Manimekalai, M.S.S, Kumar, A, Jeyakanthan, J, Gruber, G. | Deposit date: | 2011-01-24 | Release date: | 2011-10-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Conserved glycine residues in the P-loop of ATP synthases form a doorframe for nucleotide entrance. J.Mol.Biol., 413, 2011
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4B2Z
| Structure of Osh6 in complex with phosphatidylserine | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ... | Authors: | Maeda, K, Anand, K, Chiapparino, A, Kumar, A, Poletto, M, Kaksonen, M, Gavin, A.C. | Deposit date: | 2012-07-19 | Release date: | 2013-06-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Interactome Map Uncovers Phosphatidylserine Transport by Oxysterol-Binding Proteins Nature, 501, 2013
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4JC4
| Crystal structure of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa at 2.25 angstrom resolution | Descriptor: | GLYCEROL, Peptidyl-tRNA hydrolase | Authors: | Singh, A, Kumar, A, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Arora, A, Singh, T.P. | Deposit date: | 2013-02-21 | Release date: | 2013-04-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolase Biochem.J., 463, 2014
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5GIV
| Crystal structure of M32 carboxypeptidase from Deinococcus radiodurans R1 | Descriptor: | ACETATE ION, Carboxypeptidase 1, ZINC ION | Authors: | Sharma, B, Singh, R, Yadav, P, Ghosh, B, Kumar, A, Jamdar, S.N, Makde, R.D. | Deposit date: | 2016-06-25 | Release date: | 2017-07-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Active site gate of M32 carboxypeptidases illuminated by crystal structure and molecular dynamics simulations Biochim. Biophys. Acta, 1865, 2017
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5GIU
| Crystal structure of Xaa-Pro peptidase from Deinococcus radiodurans, metal-free active site | Descriptor: | PHOSPHATE ION, Proline dipeptidase, SODIUM ION | Authors: | Are, V.N, Kumar, A, Singh, R, Ghosh, B, Jamdar, S.N, Makde, R.D. | Deposit date: | 2016-06-25 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Xaa-Pro peptidase from Deinococcus radiodurans, metal-free active site To Be Published
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5GJL
| Solution structure of SUMO from Plasmodium falciparum | Descriptor: | Uncharacterized protein | Authors: | Singh, J.S, Shukla, V.K, Gujrati, M, Mishra, R.K, Kumar, A. | Deposit date: | 2016-06-30 | Release date: | 2017-08-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure, dynamics and interaction study of SUMO from Plasmodium falciparum To Be Published
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8QOT
| Structure of the mu opioid receptor bound to the antagonist nanobody NbE | Descriptor: | Anti-Fab Nanobody, Mu-type opioid receptor, NabFab HC, ... | Authors: | Yu, J, Kumar, A, Zhang, X, Martin, C, Raia, P, Manglik, A, Ballet, S, Boland, A, Stoeber, M. | Deposit date: | 2023-09-29 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural Basis of mu-Opioid Receptor-Targeting by a Nanobody Antagonist. Biorxiv, 2023
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5GIQ
| Xaa-Pro peptidase from Deinococcus radiodurans, Zinc bound | Descriptor: | PHOSPHATE ION, Proline dipeptidase, ZINC ION | Authors: | Are, V.N, Singh, R, Kumar, A, Ghosh, B, Jamdar, S.N, Makde, R.D. | Deposit date: | 2016-06-24 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases. Proteins, 2018
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5I4F
| scFv 2D10 complexed with alpha 1,6 mannobiose | Descriptor: | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, scFv 2D10 | Authors: | Vashisht, S, Kumar, A, Kaur, K.J, Salunke, D.M. | Deposit date: | 2016-02-12 | Release date: | 2016-12-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.549 Å) | Cite: | Antibodies Can Exploit Molecular Crowding to Bind New Antigens at Noncanonical Paratope Positions CHEMISTRYSELECT, 1, 2016
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4QAJ
| Crystal structure of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa at 1.5 Angstrom resolution | Descriptor: | Peptidyl-tRNA hydrolase | Authors: | Singh, A, Kumar, A, Gautam, L, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Arora, A, Singh, T.P. | Deposit date: | 2014-05-05 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolase Biochem.J., 463, 2014
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5X49
| Crystal Structure of Human mitochondrial X-prolyl Aminopeptidase (XPNPEP3) | Descriptor: | (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoic acid, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | Authors: | Singh, R, Kumar, A, Ghosh, B, Jamdar, S, Makde, R.D. | Deposit date: | 2017-02-10 | Release date: | 2017-05-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of the human aminopeptidase XPNPEP3 and comparison of its in vitro activity with Icp55 orthologs: Insights into diverse cellular processes. J. Biol. Chem., 292, 2017
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5XEV
| Crystal Structure of a novel Xaa-Pro dipeptidase from Deinococcus radiodurans | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Are, V.N, Kumar, A, Ghosh, B, Makde, R.D. | Deposit date: | 2017-04-06 | Release date: | 2017-10-18 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of a novel prolidase from Deinococcus radiodurans identifies new subfamily of bacterial prolidases. Proteins, 85, 2017
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5YZO
| Crystal structure of S9 peptidase mutant (S514A) from Deinococcus radiodurans R1 | Descriptor: | Acyl-peptide hydrolase, putative, DIMETHYL SULFOXIDE, ... | Authors: | Yadav, P, Jamdar, S.N, Kumar, A, Ghosh, B, Makde, R.D. | Deposit date: | 2017-12-15 | Release date: | 2018-11-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms. J.Biol.Chem., 294, 2019
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5YZN
| Crystal structure of S9 peptidase (active form) from Deinococcus radiodurans R1 | Descriptor: | Acyl-peptide hydrolase, putative | Authors: | Yadav, P, Jamdar, S.N, Kumar, A, Ghosh, B, Makde, R.D. | Deposit date: | 2017-12-15 | Release date: | 2018-11-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms. J.Biol.Chem., 294, 2019
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5Z40
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5YZM
| Crystal structure of S9 peptidase (inactive form) from Deinococcus radiodurans R1 | Descriptor: | ACETATE ION, Acyl-peptide hydrolase, putative | Authors: | Yadav, P, Jamdar, S.N, Kumar, A, Ghosh, B, Makde, R.D. | Deposit date: | 2017-12-15 | Release date: | 2018-11-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms. J.Biol.Chem., 294, 2019
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6A4R
| Crystal structure of aspartate bound peptidase E from Salmonella enterica | Descriptor: | ASPARTIC ACID, Peptidase E | Authors: | Yadav, P, Chandravanshi, K, Goyal, V.D, Singh, R, Kumar, A, Gokhale, S.M, Makde, R.D. | Deposit date: | 2018-06-20 | Release date: | 2018-10-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.828 Å) | Cite: | Structure of Asp-bound peptidase E from Salmonella enterica: Active site at dimer interface illuminates Asp recognition. FEBS Lett., 592, 2018
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6A4S
| Crystal structure of peptidase E with ordered active site loop from Salmonella enterica | Descriptor: | Peptidase E | Authors: | Yadav, P, Chandravanshi, K, Goyal, V.D, Singh, R, Kumar, A, Gokhale, S.M, Makde, R.D. | Deposit date: | 2018-06-20 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of Asp-bound peptidase E from Salmonella enterica: Active site at dimer interface illuminates Asp recognition. FEBS Lett., 592, 2018
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6A9U
| Crystal strcture of Icp55 from Saccharomyces cerevisiae bound to apstatin inhibitor | Descriptor: | Intermediate cleaving peptidase 55, MANGANESE (II) ION, apstatin | Authors: | Singh, R, Kumar, A, Goyal, V.D, Makde, R.D. | Deposit date: | 2018-07-16 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures and biochemical analyses of intermediate cleavage peptidase: role of dynamics in enzymatic function. FEBS Lett., 593, 2019
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6A9V
| Crystal structure of Icp55 from Saccharomyces cerevisiae (N-terminal 42 residues deletion) | Descriptor: | GLYCINE, Intermediate cleaving peptidase 55, MANGANESE (II) ION, ... | Authors: | Singh, R, Kumar, A, Goyal, V.D, Makde, R.D. | Deposit date: | 2018-07-16 | Release date: | 2019-01-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures and biochemical analyses of intermediate cleavage peptidase: role of dynamics in enzymatic function. FEBS Lett., 593, 2019
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