1K3E
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![BU of 1k3e by Molmil](/molmil-images/mine/1k3e) | Type III secretion chaperone CesT | Descriptor: | CesT | Authors: | Luo, Y, Bertero, M, Frey, E.A, Pfuetzner, R.A, Wenk, M.R, Creagh, L, Marcus, S.L, Lim, D, Finlay, B.B, Strynadka, N.C.J. | Deposit date: | 2001-10-02 | Release date: | 2001-11-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and biochemical characterization of the type III secretion chaperones CesT and SigE. Nat.Struct.Biol., 8, 2001
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1K3S
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![BU of 1k3s by Molmil](/molmil-images/mine/1k3s) | Type III Secretion Chaperone SigE | Descriptor: | PHOSPHATE ION, SigE | Authors: | Bertero, M.G, Luo, Y, Frey, E.A, Pfuetzner, R.A, Wenk, M.R, Creagh, L, Marcus, S.L, Lim, D, Finlay, B.B, Strynadka, N.C.J. | Deposit date: | 2001-10-03 | Release date: | 2001-11-28 | Last modified: | 2016-05-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and biochemical characterization of the type III secretion chaperones CesT and SigE. Nat.Struct.Biol., 8, 2001
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1LNW
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1JHH
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![BU of 1jhh by Molmil](/molmil-images/mine/1jhh) | LEXA S119A MUTANT | Descriptor: | LEXA REPRESSOR, SULFATE ION | Authors: | Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J. | Deposit date: | 2001-06-27 | Release date: | 2001-09-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of LexA: a conformational switch for regulation of self-cleavage. Cell(Cambridge,Mass.), 106, 2001
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1JHC
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![BU of 1jhc by Molmil](/molmil-images/mine/1jhc) | LEXA S119A C-TERMINAL TRYPTIC FRAGMENT | Descriptor: | LEXA REPRESSOR | Authors: | Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J. | Deposit date: | 2001-06-27 | Release date: | 2001-09-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of LexA: a conformational switch for regulation of self-cleavage. Cell(Cambridge,Mass.), 106, 2001
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1JTD
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![BU of 1jtd by Molmil](/molmil-images/mine/1jtd) | Crystal structure of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase | Descriptor: | CALCIUM ION, TEM-1 beta-lactamase, beta-lactamase inhibitor protein II | Authors: | Lim, D.C, Park, H.U, De Castro, L, Kang, S.G, Lee, H.S, Jensen, S, Lee, K.J, Strynadka, N.C.J. | Deposit date: | 2001-08-20 | Release date: | 2001-10-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure and kinetic analysis of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase. Nat.Struct.Biol., 8, 2001
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1YJ7
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![BU of 1yj7 by Molmil](/molmil-images/mine/1yj7) | Crystal structure of enteropathogenic E.coli (EPEC) type III secretion system protein EscJ | Descriptor: | GLYCEROL, PHOSPHATE ION, escJ | Authors: | Yip, C.K, Kimbrough, T.G, Felise, H.B, Vuckovic, M, Thomas, N.A, Pfuetzner, R.A, Frey, E.A, Finlay, B.B, Miller, S.I, Strynadka, N.C.J. | Deposit date: | 2005-01-13 | Release date: | 2005-06-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural characterization of the molecular platform for type III secretion system assembly. Nature, 435, 2005
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5TZ8
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![BU of 5tz8 by Molmil](/molmil-images/mine/5tz8) | Crystal structure of S. aureus TarS | Descriptor: | Glycosyl transferase | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
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5TZI
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![BU of 5tzi by Molmil](/molmil-images/mine/5tzi) | Crystal structure of S. aureus TarS 1-349 | Descriptor: | Glycosyl transferase | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
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5U02
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![BU of 5u02 by Molmil](/molmil-images/mine/5u02) | Crystal structure of S. aureus TarS 217-571 | Descriptor: | Glycosyl transferase, IMIDAZOLE | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-22 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
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5TZJ
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![BU of 5tzj by Molmil](/molmil-images/mine/5tzj) | Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc | Descriptor: | Glycosyl transferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
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5TZE
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![BU of 5tze by Molmil](/molmil-images/mine/5tze) | Crystal structure of S. aureus TarS in complex with UDP-GlcNAc | Descriptor: | Glycosyl transferase, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
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5TZK
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![BU of 5tzk by Molmil](/molmil-images/mine/5tzk) | Crystal structure of S. aureus TarS 1-349 in complex with UDP | Descriptor: | Glycosyl transferase, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. | Deposit date: | 2016-11-21 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
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5TCP
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![BU of 5tcp by Molmil](/molmil-images/mine/5tcp) | Near-atomic resolution cryo-EM structure of the periplasmic domains of PrgH and PrgK | Descriptor: | Lipoprotein PrgK, Protein PrgH | Authors: | Worrall, L.J, Hong, C, Vuckovic, M, Bergeron, J.R.C, Huang, R.K, Yu, Z, Strynadka, N.C.J. | Deposit date: | 2016-09-15 | Release date: | 2016-12-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body. Nature, 540, 2016
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5T9C
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5T9B
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5TCQ
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![BU of 5tcq by Molmil](/molmil-images/mine/5tcq) | Near-atomic resolution cryo-EM structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG | Descriptor: | Protein InvG | Authors: | Worrall, L.J, Hong, C, Vuckovic, M, Bergeron, J.R.C, Huang, R.K, Yu, Z, Strynadka, N.C.J. | Deposit date: | 2016-09-15 | Release date: | 2016-12-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body. Nature, 540, 2016
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5T91
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![BU of 5t91 by Molmil](/molmil-images/mine/5t91) | Crystal structure of B. subtilis 168 GlpQ in complex with bicine | Descriptor: | BICINE, CALCIUM ION, Glycerophosphoryl diester phosphodiesterase, ... | Authors: | Li, F.K.K, Strynadka, N.C.J. | Deposit date: | 2016-09-09 | Release date: | 2016-11-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component. J. Biol. Chem., 291, 2016
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5TCR
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![BU of 5tcr by Molmil](/molmil-images/mine/5tcr) | Atomic model of the Salmonella SPI-1 type III secretion injectisome basal body proteins InvG, PrgH, and PrgK | Descriptor: | Lipoprotein PrgK, Protein InvG, Protein PrgH | Authors: | Worrall, L.J, Hong, C, Vuckovic, M, Bergeron, J.R.C, Huang, R.K, Yu, Z, Strynadka, N.C.J. | Deposit date: | 2016-09-15 | Release date: | 2016-12-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body. Nature, 540, 2016
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7KCW
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![BU of 7kcw by Molmil](/molmil-images/mine/7kcw) | Crystal structure of S. aureus penicillin-binding protein 4 (PBP4) mutant (R200L) in complex with nafcillin | Descriptor: | (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, Penicillin-binding protein 4, ... | Authors: | Alexander, J.A, Strynadka, N.C. | Deposit date: | 2020-10-07 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | PBP4-mediated beta-lactam resistance among clinical strains of Staphylococcus aureus. J.Antimicrob.Chemother., 76, 2021
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8SXR
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![BU of 8sxr by Molmil](/molmil-images/mine/8sxr) | Crystal structure of SARS-CoV-2 Mpro with C5a | Descriptor: | 3C-like proteinase nsp5, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(5-hydroxyisoquinolin-4-yl)acetamide | Authors: | Worrall, L.J, Kenward, C, Lee, J, Strynadka, N.C.J. | Deposit date: | 2023-05-23 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.114 Å) | Cite: | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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5WCN
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6ZTG
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![BU of 6ztg by Molmil](/molmil-images/mine/6ztg) | Spor protein DedD | Descriptor: | Cell division protein DedD | Authors: | Pazos, M, Peters, K, Boes, A, Safaei, Y, Kenward, C, Caveney, N.A, Laguri, C, Breukink, E, Strynadka, N.C.J, Simorre, J.P, Terrak, M, Vollmer, W. | Deposit date: | 2020-07-20 | Release date: | 2020-11-11 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli. Mbio, 11, 2020
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2YK7
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![BU of 2yk7 by Molmil](/molmil-images/mine/2yk7) | Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP-3F-Neu5Ac. | Descriptor: | 1,2-ETHANEDIOL, CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE, CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID, ... | Authors: | Lin, L.Y.C, Rakic, B, Chiu, C.P.C, Lameignere, E, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | Deposit date: | 2011-05-25 | Release date: | 2011-08-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis J.Biol.Chem., 286, 2011
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2YK4
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![BU of 2yk4 by Molmil](/molmil-images/mine/2yk4) | Structure of Neisseria LOS-specific sialyltransferase (NST). | Descriptor: | 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL, CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE, ... | Authors: | Lin, L.Y.C, Rakic, B, Chiu, C.P.C, Lameignere, E, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | Deposit date: | 2011-05-25 | Release date: | 2011-08-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis J.Biol.Chem., 286, 2011
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