8K1N
 
 | | mycobacterial efflux pump, substrate-bound state | | Descriptor: | CARDIOLIPIN, Multidrug efflux system ATP-binding protein Rv1218c, Multidrug efflux system permease protein Rv1217c, ... | | Authors: | Wang, Y, Wu, F, Zhang, L, Rao, Z. | | Deposit date: | 2023-07-11 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | mycobacterial efflux pump, substrate-bound state
To Be Published
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8K1M
 | | mycobacterial efflux pump, apo state | | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CARDIOLIPIN, Multidrug efflux system ATP-binding protein Rv1218c, ... | | Authors: | Wang, Y, Wu, F, Zhang, L, Rao, Z. | | Deposit date: | 2023-07-11 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | mycobacterial efflux pump, apo state
To Be Published
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8K1P
 | | mycobacterial efflux pump, ADP+vanadate bound state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, ... | | Authors: | Wang, Y, Wu, F, Zhang, L, Rao, Z. | | Deposit date: | 2023-07-11 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | mycobacterial efflux pump, ADP+vanadate bound state
To Be Published
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5GZX
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8KBX
 | | Cryo-EM structure of human ATG2A-WIPI4 complex | | Descriptor: | Autophagy-related protein 2 homolog A, WD repeat domain phosphoinositide-interacting protein 4 | | Authors: | Wang, Y, Stjepanovic, G. | | Deposit date: | 2023-08-04 | | Release date: | 2024-08-07 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Structural basis for lipid transfer by the ATG2A-ATG9A complex.
Nat.Struct.Mol.Biol., 2024
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8KBY
 | | Cryo-EM structure of ATG2A | | Descriptor: | Autophagy-related protein 2 homolog A | | Authors: | Wang, Y, Stjepanovic, G. | | Deposit date: | 2023-08-04 | | Release date: | 2024-08-07 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Structural basis for lipid transfer by the ATG2A-ATG9A complex.
Nat.Struct.Mol.Biol., 2024
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8KC3
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8KAA
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5GZY
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2IL3
 | | Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | | Descriptor: | Epsilon-class Glutathione S-transferase | | Authors: | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | | Deposit date: | 2006-10-02 | | Release date: | 2007-10-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
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2IMK
 | | Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | | Descriptor: | Epsilon-class Glutathione S-transferase, S-HEXYLGLUTATHIONE | | Authors: | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | | Deposit date: | 2006-10-02 | | Release date: | 2007-10-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
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5H6Y
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2H52
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2GL9
 | | Crystal Structure of Glycosylasparaginase-Substrate Complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARAGINE, Glycosylasparaginase alpha chain, ... | | Authors: | Wang, Y, Guo, H.C. | | Deposit date: | 2006-04-04 | | Release date: | 2007-02-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystallographic snapshot of a productive glycosylasparaginase-substrate complex.
J.Mol.Biol., 366, 2007
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2K48
 | | NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein | | Descriptor: | Nucleoprotein | | Authors: | Wang, Y, Boudreaux, D.M, Estrada, D.F, Egan, C.W, St Jeor, S.C, De Guzman, R.N. | | Deposit date: | 2008-05-30 | | Release date: | 2008-08-05 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein.
J.Biol.Chem., 283, 2008
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5Y7L
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8XIO
 | | Structure of L797591-SSTR1 G protein complex | | Descriptor: | (2~{S})-~{N}-[(4~{S})-6-azanyl-2,2,4-trimethyl-hexyl]-3-naphthalen-1-yl-2-[[2-phenylethyl(2-pyridin-2-ylethyl)carbamoyl]amino]propanamide, G-alpha-i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y. | | Deposit date: | 2023-12-19 | | Release date: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
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8XIR
 | | Structure of pasireotide-SSTR3 G protein complex | | Descriptor: | G-alpha i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y. | | Deposit date: | 2023-12-19 | | Release date: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
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8XIQ
 | | Structure of L796778-SSTR3 G protein complex | | Descriptor: | G-alpha i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y. | | Deposit date: | 2023-12-19 | | Release date: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.71 Å) | | Cite: | Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
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8XIP
 | | Structure of Pasireotide-SSTR1 G protein complex | | Descriptor: | 004-DTR-LYS-TY5-PHE-A1D5E, G-alpha i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y. | | Deposit date: | 2023-12-19 | | Release date: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
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8HK5
 | | C5aR1-Gi-C5a protein complex | | Descriptor: | C5a anaphylatoxin chemotactic receptor 1, Complement C5, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Wang, Y, Liu, W, Xu, Y, Zhuang, Y, Xu, H.E. | | Deposit date: | 2022-11-24 | | Release date: | 2023-05-10 | | Last modified: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins.
Nat.Chem.Biol., 19, 2023
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8HK3
 | | C3aR-Gi-apo protein complex | | Descriptor: | C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Wang, Y, Liu, W, Xu, Y, Zhuang, Y, Xu, H.E. | | Deposit date: | 2022-11-24 | | Release date: | 2023-05-10 | | Last modified: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins.
Nat.Chem.Biol., 19, 2023
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8HK2
 | | C3aR-Gi-C3a protein complex | | Descriptor: | C3a anaphylatoxin, C3a anaphylatoxin chemotactic receptor, CHOLESTEROL, ... | | Authors: | Wang, Y, Liu, W, Xu, Y, Zhuang, Y, Xu, H.E. | | Deposit date: | 2022-11-24 | | Release date: | 2023-05-10 | | Last modified: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins.
Nat.Chem.Biol., 19, 2023
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8HYA
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7WO2
 | | SARS-CoV-2 3CLPro Peptidomimetic Inhibitor TPM5 | | Descriptor: | 3C-like proteinase, N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanylidene-3-[(3S}-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]furan-2-carboxamide | | Authors: | Wang, Y, Ye, S. | | Deposit date: | 2022-01-20 | | Release date: | 2022-12-28 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions.
Int J Mol Sci, 23, 2022
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