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3S1Q
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BU of 3s1q by Molmil
RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-16
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
1CS0
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BU of 1cs0 by Molmil
Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ...
Authors:Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M.
Deposit date:1999-08-16
Release date:1999-12-10
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
3S1M
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BU of 3s1m by Molmil
RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 1)
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*GP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-15
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
4ODE
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BU of 4ode by Molmil
Co-Crystal Structure of MDM2 with Inhibitor Compound 4
Descriptor: (2-{[(3R,5R,6S)-1-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]methyl}-1,3-thiazol-5-yl)acetic acid, E3 ubiquitin-protein ligase Mdm2, SULFATE ION
Authors:Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M.
Deposit date:2014-01-10
Release date:2014-04-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres.
J.Med.Chem., 57, 2014
3RZD
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BU of 3rzd by Molmil
RNA Polymerase II Initiation Complex with a 5-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-11
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3RZO
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BU of 3rzo by Molmil
RNA Polymerase II Initiation Complex with a 4-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-12
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S1R
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BU of 3s1r by Molmil
RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with GTP
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-16
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S16
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BU of 3s16 by Molmil
RNA Polymerase II Initiation Complex with an 8-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.241 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
4ODF
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BU of 4odf by Molmil
Co-Crystal Structure of MDM2 with Inhibitor Compound 47
Descriptor: 6-{[(2S,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid, E3 ubiquitin-protein ligase Mdm2
Authors:Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M.
Deposit date:2014-01-10
Release date:2014-04-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2006 Å)
Cite:Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres.
J.Med.Chem., 57, 2014
1C30
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BU of 1c30 by Molmil
CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ...
Authors:Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M.
Deposit date:1999-07-24
Release date:1999-12-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
1C3O
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BU of 1c3o by Molmil
CRYSTAL STRUCTURE OF THE CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTANT C269S WITH BOUND GLUTAMINE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ...
Authors:Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M.
Deposit date:1999-07-28
Release date:1999-12-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
3S17
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BU of 3s17 by Molmil
RNA Polymerase II Initiation Complex with a 9-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S15
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BU of 3s15 by Molmil
RNA Polymerase II Initiation Complex with a 7-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S2H
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BU of 3s2h by Molmil
RNA Polymerase II Initiation Complex with a 6-nt RNA containing a 2[prime]-iodo ATP
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-16
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
6WJH
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BU of 6wjh by Molmil
Crystal structure of MAGE-A11 bound to the PCF11 degron
Descriptor: Fusion protein of PCF11 and MAGE-A11
Authors:Miller, D.J, Huang, X.
Deposit date:2020-04-13
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.
Nat Commun, 11, 2020
4E55
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BU of 4e55 by Molmil
Crystal Structure of spacer removed cephalosporin acylase mutant
Descriptor: CALCIUM ION, Cephalosporin acylase
Authors:Yin, J, Zhang, Z, Wu, G, Huang, X.
Deposit date:2012-03-14
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Spacer shortened Cephalosporin acylase
To be Published
4E57
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BU of 4e57 by Molmil
Crystal Structure of spacer 6aa-shortened cephalosporin acylase mutant
Descriptor: CADMIUM ION, Cephalosporin acylase
Authors:Yin, J, Zhang, Z, Wu, G, Huang, X.
Deposit date:2012-03-14
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:spacer shortened Cephalosporin acylase
To be Published
4E56
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BU of 4e56 by Molmil
Crystal Structure of spacer 8aa-shortened cephalosporin acylase mutant
Descriptor: CALCIUM ION, Cephalosporin acylase
Authors:Yin, J, Zhang, Z, Wu, G, Huang, X.
Deposit date:2012-03-14
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:spacer shortened Cephalosporin acylase
To be Published
3GTL
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BU of 3gtl by Molmil
Backtracked RNA polymerase II complex with 13mer with G<>U mismatch
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTP
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BU of 3gtp by Molmil
Backtracked RNA polymerase II complex with 24mer RNA
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTK
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BU of 3gtk by Molmil
Backtracked RNA polymerase II complex with 18mer RNA
Descriptor: DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTM
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BU of 3gtm by Molmil
Co-complex of Backtracked RNA polymerase II with TFIIS
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTQ
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BU of 3gtq by Molmil
Backtracked RNA polymerase II complex induced by damage
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*CP*AP*TP*AP*AP*CP*CP*AP*CP*AP*GP*GP*CP*TP*CP*CP*TP*CP*TP*CP*CP*AP*TP*C)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3J6Q
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BU of 3j6q by Molmil
Identification of the active sites in the methyltransferases of a transcribing dsRNA virus
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, Structural protein VP3
Authors:Zhu, B, Yang, C, Liu, H, Cheng, L, Song, F, Zeng, S, Huang, X, Ji, G, Zhu, P.
Deposit date:2014-03-20
Release date:2014-10-08
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Identification of the active sites in the methyltransferases of a transcribing dsRNA virus.
J.Mol.Biol., 426, 2014
3GTG
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BU of 3gtg by Molmil
Backtracked RNA polymerase II complex with 12mer RNA
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.78 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009

221051

数据于2024-06-12公开中

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