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Structure of NNQQ Peptide from Yeast Prion SUP35
Descriptor:	NNQQ peptide derived from Yeast Prion Sup35
Authors:	Nelson, R, Sawaya, M.R, Eisenberg, D.
Deposit date:	2007-01-19
Release date:	2007-01-30
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.42 Å)
Cite:	Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007

2ONA

MVGGVV peptide derived from Alzheimer's A-beta, residues 35-40
Descriptor:	MVGGVV peptide derived from Alzheimer's A-beta, residues 35-40
Authors:	Sambashivan, S, Sawaya, M.R, Eisenberg, D.
Deposit date:	2007-01-23
Release date:	2007-01-30
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.03 Å)
Cite:	Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007

4NP8

Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph)
Descriptor:	Microtubule-associated protein tau
Authors:	Landau, M, Eisenberg, D, Sawaya, M.R, Dannenberg, J, Kobko, N.
Deposit date:	2013-11-20
Release date:	2013-12-18
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.51 Å)
Cite:	Molecular mechanisms for protein-encoded inheritance. Nat.Struct.Mol.Biol., 16, 2009

2OL9

Peptide corresponding to residues 170-175 of human prion
Descriptor:	peptide from human prion
Authors:	Apostol, M.A, Sawaya, M.R, Eisenberg, D.
Deposit date:	2007-01-18
Release date:	2007-01-30
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (0.85 Å)
Cite:	Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007

2OMP

LYQLEN peptide derived from human insulin chain A, residues 13-18
Descriptor:	LYQLEN peptide derived from human insulin chain A, residues 13-18
Authors:	Ivanova, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:	2007-01-22
Release date:	2007-01-30
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007

2ONV

Crystal Structure of the amyloid-fibril forming peptide GGVVIA derived from the Alzheimer's amyloid Abeta (Abeta37-42).
Descriptor:	amyloid-fibril forming peptide GGVVIA derived from the Alzheimer's amyloid Abeta
Authors:	Sambashivan, S, Sawaya, M.R, Eisenberg, D.
Deposit date:	2007-01-24
Release date:	2007-02-06
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.61 Å)
Cite:	Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007

2ONW

Structure of SSTSSA, a fibril forming peptide from Bovine Pancreatic Ribonuclease (RNase A, residues 15-20)
Descriptor:	fibril forming peptide from Bovine Pancreatic Ribonuclease (RNase A)
Authors:	Sambashivan, S, Sawaya, M.R, Eisenberg, D.
Deposit date:	2007-01-24
Release date:	2007-02-06
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.51 Å)
Cite:	Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007

1Z9W

Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis
Descriptor:	Dihydroneopterin aldolase
Authors:	Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:	2005-04-05
Release date:	2005-04-19
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. J.Mol.Biol., 349, 2005

3NVE

MMHFGN segment 138-143 from Syrian Hamster prion
Descriptor:	Major prion protein
Authors:	Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:	2010-07-08
Release date:	2011-03-02
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Atomic structures suggest determinants of transmission barriers in Mammalian prion disease. Biochemistry, 50, 2011

1YJO

Structure of NNQQNY from yeast prion Sup35 with zinc acetate
Descriptor:	ACETIC ACID, Eukaryotic peptide chain release factor GTP-binding subunit, ZINC ION
Authors:	Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D.
Deposit date:	2005-01-15
Release date:	2005-06-14
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.3 Å)
Cite:	Structure of the cross-beta spine of amyloid-like fibrils. Nature, 435, 2005

1YJP

Structure of GNNQQNY from yeast prion Sup35
Descriptor:	Eukaryotic peptide chain release factor GTP-binding subunit
Authors:	Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D.
Deposit date:	2005-01-15
Release date:	2005-06-14
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structure of the cross-beta spine of amyloid-like fibrils. Nature, 435, 2005

1YKW

Crystal Structure of a Novel RuBisCO-Like Protein from the Green Sulfur Bacterium Chlorobium tepidum
Descriptor:	RuBisCO-like protein
Authors:	Li, H, Sawaya, M.R, Tabita, F.R, Eisenberg, D.
Deposit date:	2005-01-18
Release date:	2005-05-17
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structure of a RuBisCO-like protein from the green sulfur bacterium Chlorobium tepidum. Structure, 13, 2005

2APQ

Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop.
Descriptor:	PHOSPHATE ION, Ribonuclease
Authors:	Sambashivan, S, Liu, Y, Sawaya, M.R, Gingery, M, Eisenberg, D.
Deposit date:	2005-08-16
Release date:	2005-09-13
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature, 437, 2005

3NVF

IIHFGS segment 138-143 from human prion
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, Major prion protein
Authors:	Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:	2010-07-08
Release date:	2011-03-02
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Atomic structures suggest determinants of transmission barriers in Mammalian prion disease. Biochemistry, 50, 2011

3NVG

MIHFGN segment 137-142 from mouse prion
Descriptor:	Major prion protein
Authors:	Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:	2010-07-08
Release date:	2011-03-02
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.48 Å)
Cite:	Atomic structures suggest determinants of transmission barriers in Mammalian prion disease. Biochemistry, 50, 2011

3PPD

GGVLVN segment from Human Prostatic Acid Phosphatase Residues 260-265, involved in Semen-Derived Enhancer of Viral Infection
Descriptor:	ACETIC ACID, GGVLVN peptide, amyloid forming segment, ...
Authors:	Zhao, A, Sawaya, M.R, Eisenberg, D.
Deposit date:	2010-11-24
Release date:	2011-06-29
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation. Nature, 475, 2011

2OMM

GNNQQNY peptide corresponding to residues 7-13 of yeast prion sup35
Descriptor:	GNNQQNY peptide corresponding to residues 7-13 of yeast prion sup35
Authors:	Sawaya, M.R, Nelson, R, Eisenberg, D.
Deposit date:	2007-01-22
Release date:	2007-01-30
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007

2OMQ

VEALYL peptide derived from human insulin chain B, residues 12-17
Descriptor:	VEALYL peptide derived from human insulin chain B, residues 12-17
Authors:	Ivanova, M, Sawaya, M.R, Eisenberg, D.
Deposit date:	2007-01-22
Release date:	2007-01-30
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007

3NVH

MIHFGND segment 137-143 from mouse prion
Descriptor:	Major prion protein, trifluoroacetic acid
Authors:	Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:	2010-07-08
Release date:	2011-03-02
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.61 Å)
Cite:	Atomic structures suggest determinants of transmission barriers in Mammalian prion disease. Biochemistry, 50, 2011

1N2G

Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with AMPCPP
Descriptor:	DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ETHANOL, GLYCEROL, ...
Authors:	Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:	2002-10-22
Release date:	2003-04-22
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate Protein Sci., 12, 2003

3HYD

LVEALYL peptide derived from human insulin chain B, residues 11-17
Descriptor:	Insulin
Authors:	Ivanova, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:	2009-06-22
Release date:	2009-10-06
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1 Å)
Cite:	Molecular basis for insulin fibril assembly. Proc.Natl.Acad.Sci.USA, 106, 2009

1N2E

Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with AMPCPP and pantoate
Descriptor:	DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ETHANOL, GLYCEROL, ...
Authors:	Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:	2002-10-22
Release date:	2003-04-22
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate Protein Sci., 12, 2003

1N2J

Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with pantoate
Descriptor:	BETA-ALANINE, ETHANOL, GLYCEROL, ...
Authors:	Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:	2002-10-22
Release date:	2003-04-22
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate Protein Sci., 12, 2003

3G7W

Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding Protein
Descriptor:	GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ...
Authors:	Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D.
Deposit date:	2009-02-11
Release date:	2009-06-23
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009

3G7V

Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein
Descriptor:	GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ...
Authors:	Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D.
Deposit date:	2009-02-10
Release date:	2009-06-23
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.86 Å)
Cite:	Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009

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