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8QKX
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BU of 8qkx by Molmil
Solution structure of a bimolecular quadruplex-duplex hybrid containing a V-shaped loop
Descriptor: DNA (5'-D(*CP*TP*CP*CP*AP*GP*CP*TP*GP*GP*GP*TP*GP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*GP*CP*TP*GP*GP*AP*GP*TP*T)-3')
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-09-18
Release date:2024-02-07
Method:SOLUTION NMR
Cite:Structural Aspects of Split G-Quadruplexes in Quadruplex-Duplex Hybrid Systems
Chemistryselect, 2024
8RQ4
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BU of 8rq4 by Molmil
Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in complex with probenecid
Descriptor: 4-(dipropylsulfamoyl)benzoic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL HEMISUCCINATE
Authors:Mazza, T, Beis, K.
Deposit date:2024-01-17
Release date:2024-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
8RQ3
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BU of 8rq3 by Molmil
Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in an autoinhibited state (nucleotide-free)
Descriptor: ATP-binding cassette sub-family C member 2
Authors:Mazza, T, Beis, K.
Deposit date:2024-01-17
Release date:2024-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
8RW2
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BU of 8rw2 by Molmil
Structure of a chair-type antiparallel quadruplex-duplex hybrid at pH 6
Descriptor: DNA (33-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2024-02-02
Release date:2024-03-27
Last modified:2024-06-05
Method:SOLUTION NMR
Cite:A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
8S1W
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BU of 8s1w by Molmil
Structure of a quadruplex-duplex hybrid with a (-pd+l) loop progression
Descriptor: DNA (33-MER)
Authors:Vianney, Y.M, Jana, J, Weisz, K.
Deposit date:2024-02-16
Release date:2024-03-27
Last modified:2024-06-05
Method:SOLUTION NMR
Cite:A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
1T5L
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BU of 1t5l by Molmil
Crystal structure of the DNA repair protein UvrB point mutant Y96A revealing a novel fold for domain 2
Descriptor: UvrABC system protein B, ZINC ION
Authors:Truglio, J.J, Croteau, D.L, Skorvaga, M, DellaVecchia, M.J, Theis, K, Mandavilli, B.S, Van Houten, B, Kisker, C.
Deposit date:2004-05-04
Release date:2004-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair
Embo J., 23, 2004
8R6D
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BU of 8r6d by Molmil
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology
Descriptor: DNA (31-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-11-22
Release date:2024-03-06
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
8R6H
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BU of 8r6h by Molmil
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology complexed with Phen-DC3
Descriptor: DNA (34-MER), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-11-22
Release date:2024-03-06
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
1KEW
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BU of 1kew by Molmil
The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium with thymidine diphosphate bound
Descriptor: GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H.
Deposit date:2001-11-17
Release date:2002-01-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002
6ERL
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BU of 6erl by Molmil
Quadruplex with flipped tetrad formed by the c-myc promoter sequence
Descriptor: cmbr-481317
Authors:Karg, B, Weisz, K.
Deposit date:2017-10-18
Release date:2018-06-13
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Loop Length Affects Syn-Anti Conformational Rearrangements in Parallel G-Quadruplexes.
Chemistry, 2018
1KET
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BU of 1ket by Molmil
The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with thymidine diphosphate bound
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, THYMIDINE-5'-DIPHOSPHATE, dTDP-D-glucose 4,6-dehydratase
Authors:Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H.
Deposit date:2001-11-17
Release date:2002-01-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002
1KEU
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BU of 1keu by Molmil
The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium with dTDP-D-glucose bound
Descriptor: 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, dTDP-D-glucose 4,6-dehydratase
Authors:Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H.
Deposit date:2001-11-17
Release date:2002-01-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002
1KEP
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BU of 1kep by Molmil
The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with dTDP-xylose bound
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, THYMIDINE-5'-DIPHOSPHO-BETA-D-XYLOSE, ...
Authors:Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H.
Deposit date:2001-11-16
Release date:2002-01-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002
6F4Z
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BU of 6f4z by Molmil
2'F-araG modified quadruplex with flipped G-tract and central tetrad
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*(GFL)P*GP*GP*AP*CP*GP*GP*G)-3')
Authors:Dickerhoff, J, Weisz, K.
Deposit date:2017-11-30
Release date:2018-04-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Fluorine-Mediated Editing of a G-Quadruplex Folding Pathway.
Chembiochem, 19, 2018
6FFR
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BU of 6ffr by Molmil
DNA-RNA Hybrid Quadruplex with Flipped Tetrad
Descriptor: DNA/RNA (5'-R(*G)-D(P*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*GP*AP*C)-R(P*G)-D(P*GP*G)-3')
Authors:Haase, L, Dickerhoff, J, Weisz, K.
Deposit date:2018-01-09
Release date:2018-09-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:DNA-RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies.
Chemistry, 24, 2018
2KY7
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BU of 2ky7 by Molmil
NMR Structural Studies on the Covalent DNA Binding of a Pyrrolobenzodiazepine-Naphthalimide Conjugate
Descriptor: 2-{2-[4-(3-{[(11aS)-7-methoxy-5-oxo-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepin-8-yl]oxy}propyl)piperazin-1-yl]ethyl}-1H-benzo[de]isoquinoline-1,3(2H)-dione, 5'-D(*AP*AP*CP*AP*AP*TP*TP*GP*TP*T)-3'
Authors:Rettig, M, Langel, W, Kamal, A, Weisz, K.
Deposit date:2010-05-17
Release date:2010-06-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structural studies on the covalent DNA binding of a pyrrolobenzodiazepine-naphthalimide conjugate
Org.Biomol.Chem., 8, 2010
1JRP
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BU of 1jrp by Molmil
Crystal Structure of Xanthine Dehydrogenase inhibited by alloxanthine from Rhodobacter capsulatus
Descriptor: CALCIUM ION, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Truglio, J.J, Theis, K, Leimkuhler, S, Rappa, R, Rajagopalan, K.V, Kisker, C.
Deposit date:2001-08-14
Release date:2002-01-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus
Structure, 10, 2002
1JRO
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BU of 1jro by Molmil
Crystal Structure of Xanthine Dehydrogenase from Rhodobacter capsulatus
Descriptor: CALCIUM ION, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Truglio, J.J, Theis, K, Leimkuhler, S, Rappa, R, Rajagopalan, K.V, Kisker, C.
Deposit date:2001-08-14
Release date:2002-01-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus
Structure, 10, 2002
1KER
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BU of 1ker by Molmil
The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with dTDP-D-glucose bound
Descriptor: 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H.
Deposit date:2001-11-17
Release date:2002-01-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002
1G5H
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BU of 1g5h by Molmil
CRYSTAL STRUCTURE OF THE ACCESSORY SUBUNIT OF MURINE MITOCHONDRIAL POLYMERASE GAMMA
Descriptor: GLYCEROL, MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT, SODIUM ION
Authors:Carrodeguas, J.A, Theis, K, Bogenhagen, D.F, Kisker, C.
Deposit date:2000-11-01
Release date:2001-03-14
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer.
Mol.Cell, 7, 2001
1G5I
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BU of 1g5i by Molmil
CRYSTAL STRUCTURE OF THE ACCESSORY SUBUNIT OF MURINE MITOCHONDRIAL POLYMERASE GAMMA
Descriptor: GLYCEROL, MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT, SODIUM ION
Authors:Carrodeguas, J.A, Theis, K, Bogenhagen, D.F, Kisker, C.
Deposit date:2000-11-01
Release date:2001-03-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer.
Mol.Cell, 7, 2001
4ADO
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BU of 4ado by Molmil
Fusidic acid resistance protein FusB
Descriptor: FAR1, ZINC ION
Authors:Guo, X, Peisker, K, Backbro, K, Chen, Y, Kiran, R.K, Sanyal, S, Selmer, M.
Deposit date:2011-12-31
Release date:2012-03-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Function of Fusb: An Elongation Factor G-Binding Fusidic Acid Resistance Protein Active in Ribosomal Translocation and Recycling
Open Biol., 2, 2012
4ADN
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BU of 4adn by Molmil
Fusidic acid resistance protein FusB
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FAR1, ...
Authors:Guo, X, Peisker, K, Backbro, K, Chen, Y, Kiran, R.K, Sanyal, S, Selmer, M.
Deposit date:2011-12-31
Release date:2012-03-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and Function of Fusb: An Elongation Factor G-Binding Fusidic Acid Resistance Protein Active in Ribosomal Translocation and Recycling
Open Biol., 2, 2012
5OV2
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BU of 5ov2 by Molmil
2'F-ANA-G modified quadruplex with a flipped tetrad
Descriptor: artificial quadruplex with propeller, diagonal, and lateral loop
Authors:Dickerhoff, J, Weisz, K.
Deposit date:2017-08-27
Release date:2017-10-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Nonconventional C-HF Hydrogen Bonds Support a Tetrad Flip in Modified G-Quadruplexes.
J Phys Chem Lett, 8, 2017
4B09
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BU of 4b09 by Molmil
Structure of unphosphorylated BaeR dimer
Descriptor: HEXATANTALUM DODECABROMIDE, TRANSCRIPTIONAL REGULATORY PROTEIN BAER
Authors:Choudhury, H, Beis, K.
Deposit date:2012-06-29
Release date:2013-07-10
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Dimeric Form of the Unphosphorylated Response Regulator Baer.
Protein Sci., 22, 2013

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数据于2024-10-16公开中

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