2XZO
 
 | | Upf1 helicase - RNA complex | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E. | | Deposit date: | 2010-11-26 | | Release date: | 2011-03-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.395 Å) | | Cite: | Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
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2X19
 | | Crystal structure of Importin13 - RanGTP complex | | Descriptor: | GTP-BINDING NUCLEAR PROTEIN GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN-13, ... | | Authors: | Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. | | Deposit date: | 2009-12-23 | | Release date: | 2010-02-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13.
Mol.Cell, 37, 2010
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2XZL
 | | Upf1-RNA complex | | Descriptor: | 5- R(*UP*UP*UP*UP*UP*UP*UP*UP*U) -3, ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HELICASE NAM7, ... | | Authors: | Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E. | | Deposit date: | 2010-11-26 | | Release date: | 2011-03-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
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5AOR
 | | Structure of MLE RNA ADP AlF4 complex | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, DOSAGE COMPENSATION REGULATOR, ... | | Authors: | Prabu, J.R, Conti, E. | | Deposit date: | 2015-09-11 | | Release date: | 2015-11-18 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structure of the RNA Helicase Mle Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling.
Mol.Cell, 60, 2015
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5ANR
 | | Structure of a human 4E-T - DDX6 - CNOT1 complex | | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | | Authors: | Basquin, J, Oezguer, S, Conti, E. | | Deposit date: | 2015-09-08 | | Release date: | 2015-10-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Structure of a Human 4E-T/Ddx6/Cnot1 Complex Reveals the Different Interplay of Ddx6-Binding Proteins with the Ccr4-not Complex.
Cell Rep., 13, 2015
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2J0A
 | | Structure of the catalytic domain of mouse Manic Fringe | | Descriptor: | BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, POTASSIUM ION, SULFATE ION | | Authors: | Jinek, M, Chen, Y.-W, Clausen, H, Cohen, S.M, Conti, E. | | Deposit date: | 2006-08-01 | | Release date: | 2006-09-04 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe
Nat.Struct.Mol.Biol., 13, 2006
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2J0B
 | | Structure of the catalytic domain of mouse Manic Fringe in complex with UDP and manganese | | Descriptor: | BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, MANGANESE (II) ION, POTASSIUM ION, ... | | Authors: | Jinek, M, Chen, Y.-W, Clausen, H, Cohen, S.M, Conti, E. | | Deposit date: | 2006-08-01 | | Release date: | 2006-09-04 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe
Nat.Struct.Mol.Biol., 13, 2006
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5MZN
 | | Helicase Sen1 | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Leonaite, B, Basquin, J, Conti, E. | | Deposit date: | 2017-02-01 | | Release date: | 2017-04-19 | | Last modified: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.787 Å) | | Cite: | Sen1 has unique structural features grafted on the architecture of the Upf1-like helicase family.
EMBO J., 36, 2017
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5NKM
 | | SMG8-SMG9 complex | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Li, L, Basquin, J, Conti, E. | | Deposit date: | 2017-03-31 | | Release date: | 2017-04-19 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.493 Å) | | Cite: | Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
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5OKZ
 | | Crystal Strucrure of the Mpp6 Exosome complex | | Descriptor: | CHLORIDE ION, Exosome complex component CSL4, Exosome complex component MTR3, ... | | Authors: | Falk, S, Ebert, J, Conti, E. | | Deposit date: | 2017-07-26 | | Release date: | 2017-08-30 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.200039 Å) | | Cite: | Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase.
Cell Rep, 20, 2017
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5NKK
 | | SMG8-SMG9 complex GDP bound | | Descriptor: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Li, L, Basquin, J, Conti, E. | | Deposit date: | 2017-03-31 | | Release date: | 2017-04-19 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
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4BA2
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4BA1
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4B8A
 | | Structure of yeast NOT1 MIF4G domain co-crystallized with CAF1 | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, POLY(A) RIBONUCLEASE POP2 | | Authors: | Basquin, J, Conti, E. | | Deposit date: | 2012-08-26 | | Release date: | 2012-11-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
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4AJ5
 | | Crystal structure of the Ska core complex | | Descriptor: | SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1, SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2, SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3 | | Authors: | Jeyaprakash, A.A, Santamaria, A, Jayachandran, U, Chan, Y.W, Benda, C, Nigg, E.A, Conti, E. | | Deposit date: | 2012-02-15 | | Release date: | 2012-05-23 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.32 Å) | | Cite: | Structural and Functional Organization of the Ska Complex, a Key Component of the Kinetochore-Microtubule Interface.
Mol.Cell, 46, 2012
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4A0I
 | | Crystal structure of Survivin bound to the N-terminal tail of hSgo1 | | Descriptor: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, SHUGOSHIN-LIKE 1, ZINC ION | | Authors: | Jeyaprakash, A.A, Basquin, C, Jayachandran, U, Conti, E. | | Deposit date: | 2011-09-09 | | Release date: | 2011-11-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.605 Å) | | Cite: | Structural Basis for the Recognition of Phosphorylated Histone H3 by the Survivin Subunit of the Chromosomal Passenger Complex.
Structure, 19, 2011
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4A0J
 | | Crystal structure of Survivin bound to the phosphorylated N-terminal tail of histone H3 | | Descriptor: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, HISTONE H3 PEPTIDE, ZINC ION | | Authors: | Jeyaprakash, A.A, Basquin, C, Jayachandran, U, Conti, E. | | Deposit date: | 2011-09-09 | | Release date: | 2011-11-09 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.803 Å) | | Cite: | Structural Basis for the Recognition of Phosphorylated Histone H3 by the Survivin Subunit of the Chromosomal Passenger Complex.
Structure, 19, 2011
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4A90
 | | Crystal structure of mouse SAP18 residues 1-143 | | Descriptor: | GLYCEROL, HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 | | Authors: | Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E. | | Deposit date: | 2011-11-22 | | Release date: | 2012-03-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
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4A0N
 | | Crystal structure of Survivin bound to the phosphorylated N-terminal tail of histone H3 | | Descriptor: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, HISTONE H3 PEPTIDE, ZINC ION | | Authors: | Jeyaprakash, A.A, Basquin, C, Jayachandran, U, Conti, E. | | Deposit date: | 2011-09-09 | | Release date: | 2011-11-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.743 Å) | | Cite: | Structural Basis for the Recognition of Phosphorylated Histone H3 by the Survivin Subunit of the Chromosomal Passenger Complex.
Structure, 19, 2011
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4B8B
 | | N-Terminal domain of the yeast Not1 | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, GOLD ION | | Authors: | Basquin, J, Conti, E. | | Deposit date: | 2012-08-26 | | Release date: | 2012-11-21 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.801 Å) | | Cite: | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
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4A6Q
 | | Crystal structure of mouse SAP18 residues 6-143 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18, ISOPROPYL ALCOHOL | | Authors: | Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E. | | Deposit date: | 2011-11-08 | | Release date: | 2012-03-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
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4A4K
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4B89
 | | MIF4G domain of the yeast Not1 | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1 | | Authors: | Basquin, J, Conti, E. | | Deposit date: | 2012-08-26 | | Release date: | 2012-11-21 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
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4B8C
 | | nuclease module of the yeast Ccr4-Not complex | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, GLUCOSE-REPRESSIBLE ALCOHOL DEHYDROGENASE TRANSCRIPTIONAL EFFECTOR, POLY(A) RIBONUCLEASE POP2 | | Authors: | Basquin, J, Conti, E. | | Deposit date: | 2012-08-26 | | Release date: | 2012-11-21 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
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4A8X
 | | Structure of the core ASAP complex | | Descriptor: | HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18, HOOK-LIKE, ISOFORM A, ... | | Authors: | Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E. | | Deposit date: | 2011-11-21 | | Release date: | 2012-03-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
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