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5QTG
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BU of 5qtg by Molmil
T. brucei FPPS in complex with CID 126782062
Descriptor: 2-fluoro-N,3-dimethylbenzene-1-sulfonamide, Farnesyl pyrophosphate synthase, GLYCEROL, ...
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W.
Deposit date:2019-08-09
Release date:2020-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:T. brucei FPPS in complex with CID 126782062
To Be Published
5QTF
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BU of 5qtf by Molmil
T. brucei FPPS in complex with CID 144539
Descriptor: 1-(3-chloro-4-fluorophenyl)methanamine, Farnesyl pyrophosphate synthase, GLYCEROL, ...
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W.
Deposit date:2019-08-09
Release date:2020-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.783 Å)
Cite:T. brucei FPPS in complex with CID 144539
To Be Published
5QTH
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BU of 5qth by Molmil
T. brucei FPPS in complex with CID 2799882
Descriptor: Farnesyl pyrophosphate synthase, GLYCEROL, N,N-dimethyl-2-(methylsulfanyl)pyridine-3-carboxamide, ...
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W.
Deposit date:2019-08-09
Release date:2020-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.887 Å)
Cite:T. brucei FPPS in complex with CID 2799882
To Be Published
5QT9
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BU of 5qt9 by Molmil
T. brucei FPPS in complex with CID 23155989
Descriptor: (1S)-3-chloro-1-(4-methylpiperazin-1-yl)-1,4-dihydroisoquinoline, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W.
Deposit date:2019-08-07
Release date:2020-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:T. brucei FPPS in complex with CID 23155989
To Be Published
5QTI
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BU of 5qti by Molmil
T. brucei FPPS in complex with CID 62483448
Descriptor: 3-(2-bromophenoxy)pyridazine, Farnesyl pyrophosphate synthase, GLYCEROL, ...
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W.
Deposit date:2019-08-09
Release date:2020-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.112 Å)
Cite:T. brucei FPPS in complex with CID 62483448
To Be Published
5QTB
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BU of 5qtb by Molmil
T. brucei FPPS in complex with CID 303798
Descriptor: DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, Farnesyl pyrophosphate synthase, ...
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W.
Deposit date:2019-08-07
Release date:2020-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.965 Å)
Cite:T. brucei FPPS in complex with CID 303798
To Be Published
5QTJ
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BU of 5qtj by Molmil
T. brucei FPPS in complex with CID 47256035
Descriptor: Farnesyl pyrophosphate synthase, GLYCEROL, N-[(2-chloro-6-fluorophenyl)methyl]-N,2-dimethylpyrimidine-4-carboxamide, ...
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W.
Deposit date:2019-08-09
Release date:2020-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:T. brucei FPPS in complex with CID 47256035
To Be Published
5QTA
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BU of 5qta by Molmil
T. brucei FPPS in complex with CID 2804072
Descriptor: 1,3-dichloro-2-[(methylsulfonyl)methyl]benzene, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W.
Deposit date:2019-08-07
Release date:2020-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.113 Å)
Cite:T. brucei FPPS in complex with CID 2804072
To Be Published
6R37
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BU of 6r37 by Molmil
T. brucei FPPS in complex with 2-(5-chlorobenzo[b]thiophen-3-yl)acetic acid
Descriptor: (5-chloro-1-benzothiophen-3-yl)acetic acid, DIMETHYL SULFOXIDE, Farnesyl pyrophosphate synthase
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W.
Deposit date:2019-03-19
Release date:2020-04-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery
Thesis, 2019
6R38
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BU of 6r38 by Molmil
T. brucei FPPS in complex with 2-(2,5-dichlorobenzo[b]thiophen-3-yl)acetic acid
Descriptor: 2-[2,5-bis(chloranyl)-1-benzothiophen-3-yl]ethanoic acid, DIMETHYL SULFOXIDE, Farnesyl pyrophosphate synthase
Authors:Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W.
Deposit date:2019-03-19
Release date:2020-04-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery
Thesis, 2019
2L56
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BU of 2l56 by Molmil
NMR structure of the GCN4 trigger peptide refined using biased molecular dynamics simulations
Descriptor: General control protein GCN4
Authors:Missimer, J.H, Dolenc, J, Steinmetz, M.O, van Gunsteren, W.F.
Deposit date:2010-10-26
Release date:2010-12-01
Last modified:2011-10-26
Method:SOLUTION NMR
Cite:Exploring the trigger sequence of the GCN4 coiled-coil: Biased molecular dynamics resolves apparent inconsistencies in NMR measurements
Protein Sci., 19, 2010

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数据于2024-08-28公开中

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