8TM4
 
 | Human pre 13S proteasome assembly intermediate | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | Authors: | Zhang, H, Zhao, J. | Deposit date: | 2023-07-28 | Release date: | 2024-10-23 | Last modified: | 2025-05-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of human 20S proteasome biogenesis. Nat Commun, 15, 2024
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8TM5
 
 | Human mixed 13S proteasome assembly intermediate | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | Authors: | Zhang, H, Zhao, J. | Deposit date: | 2023-07-28 | Release date: | 2024-10-23 | Last modified: | 2025-05-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of human 20S proteasome biogenesis. Nat Commun, 15, 2024
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8TM3
 
 | Human proteasome alpha ring assembly intermediate | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ... | Authors: | Zhang, H, Zhao, J. | Deposit date: | 2023-07-28 | Release date: | 2024-10-23 | Last modified: | 2025-05-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of human 20S proteasome biogenesis. Nat Commun, 15, 2024
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8TM6
 
 | Human premature 20S proteasome assembly intermediate | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | Authors: | Zhang, H, Zhao, J. | Deposit date: | 2023-07-28 | Release date: | 2024-10-23 | Last modified: | 2025-05-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of human 20S proteasome biogenesis. Nat Commun, 15, 2024
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5X0Z
 
 | Crystal structure of FliM-SpeE complex from H. pylori | Descriptor: | CITRATE ANION, Flagellar motor switch protein (FliM), Polyamine aminopropyltransferase | Authors: | Zhang, H, Au, S.W.N. | Deposit date: | 2017-01-23 | Release date: | 2017-09-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A putative spermidine synthase interacts with flagellar switch protein FliM and regulates motility in Helicobacter pylori Mol. Microbiol., 106, 2017
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9K7N
 
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9K7B
 
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8WFN
 
 | Cryo-EM structure of DSR2-TTP | Descriptor: | SIR2-like domain-containing protein, tail tube protein(TTP) | Authors: | Zhang, H, Li, Z, Li, X.Z. | Deposit date: | 2023-09-19 | Release date: | 2024-05-01 | Last modified: | 2025-07-02 | Method: | ELECTRON MICROSCOPY (4.48 Å) | Cite: | Cryo-EM structure of DSR2-TTP To Be Published
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2N28
 
 | Solid-state NMR structure of Vpu | Descriptor: | Protein Vpu | Authors: | Zhang, H, Lin, E.C, Tian, Y, Das, B.B, Opella, S.J. | Deposit date: | 2015-05-01 | Release date: | 2015-09-30 | Last modified: | 2024-05-01 | Method: | SOLID-STATE NMR | Cite: | Structural determination of virus protein U from HIV-1 by NMR in membrane environments. Biochim.Biophys.Acta, 1848, 2015
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2N29
 
 | Solution-state NMR structure of Vpu cytoplasmic domain | Descriptor: | Protein Vpu | Authors: | Zhang, H, Lin, E.C, Tian, Y, Das, B.B, Opella, S.J. | Deposit date: | 2015-05-01 | Release date: | 2015-09-30 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural determination of virus protein U from HIV-1 by NMR in membrane environments. Biochim.Biophys.Acta, 1848, 2015
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8KCB
 
 | Complex of DDM1-nucleosome(H2A) complex with DDM1 bound to SHL2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Zhang, H, Zhang, Y. | Deposit date: | 2023-08-07 | Release date: | 2024-06-26 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures. Structure, 32, 2024
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8KCC
 
 | Complex of DDM1-nucleosome(H2A.W) complex with DDM1 bound to SHL2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Zhang, H, Zhang, Y. | Deposit date: | 2023-08-07 | Release date: | 2024-06-26 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures. Structure, 32, 2024
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8OR1
 
 | Co-crystal strucutre of PD-L1 with low molecular weight inhibitor | Descriptor: | 5-[[5-[[2-chloranyl-3-(2-fluorophenyl)phenyl]methoxy]-2-[(~{E})-2-hydroxyethyliminomethyl]phenoxy]methyl]pyridine-3-carbonitrile, Programmed cell death 1 ligand 1 | Authors: | Zhang, H, Zhou, S, Wu, C, Zhu, M, Yu, Q, Wang, X, Awadasseid, A, Plewka, J, Magiera-Mularz, K, Wu, Y, Zhang, W. | Deposit date: | 2023-04-12 | Release date: | 2023-08-02 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2,2'-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors. J.Med.Chem., 66, 2023
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6O1T
 
 | BOVINE SALIVARY PROTEIN FORM 30B WITH OLEIC ACID | Descriptor: | CALCIUM ION, OLEIC ACID, Short palate, ... | Authors: | Zhang, H, Arcus, V.L. | Deposit date: | 2019-02-21 | Release date: | 2019-03-13 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The three dimensional structure of Bovine Salivary Protein 30b (BSP30b) and its interaction with specific rumen bacteria. Plos One, 14, 2019
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7W72
 
 | Structure of a human glycosylphosphatidylinositol (GPI) transamidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GPI transamidase component PIG-S, ... | Authors: | Zhang, H, Su, J, Li, B, Gao, Y, Zhang, X.C, Zhao, Y. | Deposit date: | 2021-12-02 | Release date: | 2022-02-16 | Last modified: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of human glycosylphosphatidylinositol transamidase. Nat.Struct.Mol.Biol., 29, 2022
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5UNF
 
 | XFEL structure of human angiotensin II type 2 receptor (Monoclinic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]) | Descriptor: | Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562, N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide | Authors: | Zhang, H, Han, G.W, Batyuk, A, Ishchenko, A, White, K.L, Patel, N, Sadybekov, A, Zamlynny, B, Rudd, M.T, Hollenstein, K, Tolstikova, A, White, T.A, Hunter, M.S, Weierstall, U, Liu, W, Babaoglu, K, Moore, E.L, Katz, R.D, Shipman, J.M, Garcia-Calvo, M, Sharma, S, Sheth, P, Soisson, S.M, Stevens, R.C, Katritch, V, Cherezov, V. | Deposit date: | 2017-01-30 | Release date: | 2017-04-05 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for selectivity and diversity in angiotensin II receptors. Nature, 544, 2017
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8YR2
 
 | Structure of NET-Nisoxetine in outward-open state | Descriptor: | CHLORIDE ION, CHOLESTEROL, SODIUM ION, ... | Authors: | Zhang, H, Xu, E.H, Jiang, Y. | Deposit date: | 2024-03-20 | Release date: | 2024-05-29 | Last modified: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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8VAJ
 
 | Human Argonaute3 bound to cityRNA and target RNA | Descriptor: | Protein argonaute-3, RNA (5'-R(P*(SRA)P*AP*GP*CP*AP*CP*UP*UP*UP*AP*AP*A)-3'), RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*G)-3') | Authors: | Zhang, H, Sim, G, Adhav, V.A, Nakanishi, K. | Deposit date: | 2023-12-11 | Release date: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Target cleavage and gene silencing by Argonautes with cityRNAs. Cell Rep, 43, 2024
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5UNH
 
 | Synchrotron structure of human angiotensin II type 2 receptor in complex with compound 2 (N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'- biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide) | Descriptor: | N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide, Soluble cytochrome b562,Type-2 angiotensin II receptor | Authors: | Zhang, H, Han, G.W, Batyuk, A, Ishchenko, A, White, K.L, Patel, N, Sadybekov, A, Zamlynny, B, Rudd, M.T, Hollenstein, K, Tolstikova, A, White, T.A, Hunter, M.S, Weierstall, U, Liu, W, Babaoglu, K, Moore, E.L, Katz, R.D, Shipman, J.M, Garcia-Calvo, M, Sharma, S, Sheth, P, Soisson, S.M, Stevens, R.C, Katritch, V, Cherezov, V. | Deposit date: | 2017-01-30 | Release date: | 2017-04-05 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for selectivity and diversity in angiotensin II receptors. Nature, 544, 2017
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8Y91
 
 | Structure of NET-nomifensine in outward-open state | Descriptor: | (4S)-2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine, CHLORIDE ION, SODIUM ION, ... | Authors: | Zhang, H, Xu, E.H, Jiang, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-05-29 | Last modified: | 2025-07-02 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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8Y92
 
 | structure of NET-Atomoxetine in outward-open state | Descriptor: | (3R)-N-methyl-3-(2-methylphenoxy)-3-phenyl-propan-1-amine, CHLORIDE ION, SODIUM ION, ... | Authors: | Zhang, H, Xu, E.H, Jiang, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-05-29 | Last modified: | 2025-06-18 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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8Y93
 
 | Structure of NET-Amitriptyline in outward-open state | Descriptor: | Amitriptyline, CHLORIDE ION, SODIUM ION, ... | Authors: | Zhang, H, Xu, E.H, Jiang, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-05-29 | Last modified: | 2025-06-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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8Y90
 
 | Structure of NET-Nefopam in outward-open state | Descriptor: | (1S)-5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine, CHLORIDE ION, SODIUM ION, ... | Authors: | Zhang, H, Xu, E.H, Jiang, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-05-29 | Last modified: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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8Y8Z
 
 | Structure of NET-Maprotiline in outward-open state | Descriptor: | CHLORIDE ION, SODIUM ION, Sodium-dependent noradrenaline transporter, ... | Authors: | Zhang, H, Xu, E.H, Jiang, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-05-29 | Last modified: | 2025-07-02 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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8Y95
 
 | Structure of NET-NE in Occluded state | Descriptor: | CHLORIDE ION, Noradrenaline, SODIUM ION, ... | Authors: | Zhang, H, Xu, H.E, Jiang, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-05-29 | Last modified: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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