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8TM4
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BU of 8tm4 by Molmil
Human pre 13S proteasome assembly intermediate
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Zhang, H, Zhao, J.
Deposit date:2023-07-28
Release date:2024-10-23
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of human 20S proteasome biogenesis.
Nat Commun, 15, 2024
8TM5
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BU of 8tm5 by Molmil
Human mixed 13S proteasome assembly intermediate
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Zhang, H, Zhao, J.
Deposit date:2023-07-28
Release date:2024-10-23
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of human 20S proteasome biogenesis.
Nat Commun, 15, 2024
8TM3
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BU of 8tm3 by Molmil
Human proteasome alpha ring assembly intermediate
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ...
Authors:Zhang, H, Zhao, J.
Deposit date:2023-07-28
Release date:2024-10-23
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of human 20S proteasome biogenesis.
Nat Commun, 15, 2024
8TM6
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BU of 8tm6 by Molmil
Human premature 20S proteasome assembly intermediate
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Zhang, H, Zhao, J.
Deposit date:2023-07-28
Release date:2024-10-23
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of human 20S proteasome biogenesis.
Nat Commun, 15, 2024
5X0Z
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BU of 5x0z by Molmil
Crystal structure of FliM-SpeE complex from H. pylori
Descriptor: CITRATE ANION, Flagellar motor switch protein (FliM), Polyamine aminopropyltransferase
Authors:Zhang, H, Au, S.W.N.
Deposit date:2017-01-23
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A putative spermidine synthase interacts with flagellar switch protein FliM and regulates motility in Helicobacter pylori
Mol. Microbiol., 106, 2017
9K7N
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BU of 9k7n by Molmil
Cryo-EM structure of human taurine transporter TAUT bound taurine in an occluded state in the saposin-disc
Descriptor: 2-AMINOETHANESULFONIC ACID, CHLORIDE ION, Sodium- and chloride-dependent taurine transporter
Authors:Zhang, H, Xu, E.H.
Deposit date:2024-10-24
Release date:2025-02-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of human taurine transporter TAUT bound taurine in an occluded state in the saposin-disc
Cell Res., 2025
9K7B
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BU of 9k7b by Molmil
Cryo-EM structure of human taurine transporter TauT bound with taurine molecules in an inward-open state in the saposin-disc
Descriptor: 2-AMINOETHANESULFONIC ACID, CHLORIDE ION, CHOLESTEROL, ...
Authors:Zhang, H, Xu, E.H.
Deposit date:2024-10-23
Release date:2025-02-26
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Cryo-EM structure of human taurine transporter TauT bound with taurine molecules in an inward-open state in the saposin-disc
Cell Res., 2025
8WFN
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BU of 8wfn by Molmil
Cryo-EM structure of DSR2-TTP
Descriptor: SIR2-like domain-containing protein, tail tube protein(TTP)
Authors:Zhang, H, Li, Z, Li, X.Z.
Deposit date:2023-09-19
Release date:2024-05-01
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (4.48 Å)
Cite:Cryo-EM structure of DSR2-TTP
To Be Published
2N28
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BU of 2n28 by Molmil
Solid-state NMR structure of Vpu
Descriptor: Protein Vpu
Authors:Zhang, H, Lin, E.C, Tian, Y, Das, B.B, Opella, S.J.
Deposit date:2015-05-01
Release date:2015-09-30
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Structural determination of virus protein U from HIV-1 by NMR in membrane environments.
Biochim.Biophys.Acta, 1848, 2015
2N29
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BU of 2n29 by Molmil
Solution-state NMR structure of Vpu cytoplasmic domain
Descriptor: Protein Vpu
Authors:Zhang, H, Lin, E.C, Tian, Y, Das, B.B, Opella, S.J.
Deposit date:2015-05-01
Release date:2015-09-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural determination of virus protein U from HIV-1 by NMR in membrane environments.
Biochim.Biophys.Acta, 1848, 2015
8KCB
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BU of 8kcb by Molmil
Complex of DDM1-nucleosome(H2A) complex with DDM1 bound to SHL2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Zhang, H, Zhang, Y.
Deposit date:2023-08-07
Release date:2024-06-26
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures.
Structure, 32, 2024
8KCC
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BU of 8kcc by Molmil
Complex of DDM1-nucleosome(H2A.W) complex with DDM1 bound to SHL2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Zhang, H, Zhang, Y.
Deposit date:2023-08-07
Release date:2024-06-26
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures.
Structure, 32, 2024
8OR1
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BU of 8or1 by Molmil
Co-crystal strucutre of PD-L1 with low molecular weight inhibitor
Descriptor: 5-[[5-[[2-chloranyl-3-(2-fluorophenyl)phenyl]methoxy]-2-[(~{E})-2-hydroxyethyliminomethyl]phenoxy]methyl]pyridine-3-carbonitrile, Programmed cell death 1 ligand 1
Authors:Zhang, H, Zhou, S, Wu, C, Zhu, M, Yu, Q, Wang, X, Awadasseid, A, Plewka, J, Magiera-Mularz, K, Wu, Y, Zhang, W.
Deposit date:2023-04-12
Release date:2023-08-02
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2,2'-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors.
J.Med.Chem., 66, 2023
6O1T
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BU of 6o1t by Molmil
BOVINE SALIVARY PROTEIN FORM 30B WITH OLEIC ACID
Descriptor: CALCIUM ION, OLEIC ACID, Short palate, ...
Authors:Zhang, H, Arcus, V.L.
Deposit date:2019-02-21
Release date:2019-03-13
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The three dimensional structure of Bovine Salivary Protein 30b (BSP30b) and its interaction with specific rumen bacteria.
Plos One, 14, 2019
7W72
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BU of 7w72 by Molmil
Structure of a human glycosylphosphatidylinositol (GPI) transamidase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GPI transamidase component PIG-S, ...
Authors:Zhang, H, Su, J, Li, B, Gao, Y, Zhang, X.C, Zhao, Y.
Deposit date:2021-12-02
Release date:2022-02-16
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of human glycosylphosphatidylinositol transamidase.
Nat.Struct.Mol.Biol., 29, 2022
5UNF
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BU of 5unf by Molmil
XFEL structure of human angiotensin II type 2 receptor (Monoclinic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl])
Descriptor: Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562, N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide
Authors:Zhang, H, Han, G.W, Batyuk, A, Ishchenko, A, White, K.L, Patel, N, Sadybekov, A, Zamlynny, B, Rudd, M.T, Hollenstein, K, Tolstikova, A, White, T.A, Hunter, M.S, Weierstall, U, Liu, W, Babaoglu, K, Moore, E.L, Katz, R.D, Shipman, J.M, Garcia-Calvo, M, Sharma, S, Sheth, P, Soisson, S.M, Stevens, R.C, Katritch, V, Cherezov, V.
Deposit date:2017-01-30
Release date:2017-04-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
8YR2
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BU of 8yr2 by Molmil
Structure of NET-Nisoxetine in outward-open state
Descriptor: CHLORIDE ION, CHOLESTEROL, SODIUM ION, ...
Authors:Zhang, H, Xu, E.H, Jiang, Y.
Deposit date:2024-03-20
Release date:2024-05-29
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8VAJ
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BU of 8vaj by Molmil
Human Argonaute3 bound to cityRNA and target RNA
Descriptor: Protein argonaute-3, RNA (5'-R(P*(SRA)P*AP*GP*CP*AP*CP*UP*UP*UP*AP*AP*A)-3'), RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*G)-3')
Authors:Zhang, H, Sim, G, Adhav, V.A, Nakanishi, K.
Deposit date:2023-12-11
Release date:2024-10-16
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Target cleavage and gene silencing by Argonautes with cityRNAs.
Cell Rep, 43, 2024
5UNH
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BU of 5unh by Molmil
Synchrotron structure of human angiotensin II type 2 receptor in complex with compound 2 (N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'- biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide)
Descriptor: N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide, Soluble cytochrome b562,Type-2 angiotensin II receptor
Authors:Zhang, H, Han, G.W, Batyuk, A, Ishchenko, A, White, K.L, Patel, N, Sadybekov, A, Zamlynny, B, Rudd, M.T, Hollenstein, K, Tolstikova, A, White, T.A, Hunter, M.S, Weierstall, U, Liu, W, Babaoglu, K, Moore, E.L, Katz, R.D, Shipman, J.M, Garcia-Calvo, M, Sharma, S, Sheth, P, Soisson, S.M, Stevens, R.C, Katritch, V, Cherezov, V.
Deposit date:2017-01-30
Release date:2017-04-05
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
8Y91
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BU of 8y91 by Molmil
Structure of NET-nomifensine in outward-open state
Descriptor: (4S)-2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine, CHLORIDE ION, SODIUM ION, ...
Authors:Zhang, H, Xu, E.H, Jiang, Y.
Deposit date:2024-02-06
Release date:2024-05-29
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y92
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BU of 8y92 by Molmil
structure of NET-Atomoxetine in outward-open state
Descriptor: (3R)-N-methyl-3-(2-methylphenoxy)-3-phenyl-propan-1-amine, CHLORIDE ION, SODIUM ION, ...
Authors:Zhang, H, Xu, E.H, Jiang, Y.
Deposit date:2024-02-06
Release date:2024-05-29
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y93
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BU of 8y93 by Molmil
Structure of NET-Amitriptyline in outward-open state
Descriptor: Amitriptyline, CHLORIDE ION, SODIUM ION, ...
Authors:Zhang, H, Xu, E.H, Jiang, Y.
Deposit date:2024-02-06
Release date:2024-05-29
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y90
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BU of 8y90 by Molmil
Structure of NET-Nefopam in outward-open state
Descriptor: (1S)-5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine, CHLORIDE ION, SODIUM ION, ...
Authors:Zhang, H, Xu, E.H, Jiang, Y.
Deposit date:2024-02-06
Release date:2024-05-29
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y8Z
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BU of 8y8z by Molmil
Structure of NET-Maprotiline in outward-open state
Descriptor: CHLORIDE ION, SODIUM ION, Sodium-dependent noradrenaline transporter, ...
Authors:Zhang, H, Xu, E.H, Jiang, Y.
Deposit date:2024-02-06
Release date:2024-05-29
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y95
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BU of 8y95 by Molmil
Structure of NET-NE in Occluded state
Descriptor: CHLORIDE ION, Noradrenaline, SODIUM ION, ...
Authors:Zhang, H, Xu, H.E, Jiang, Y.
Deposit date:2024-02-06
Release date:2024-05-29
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024

238582

数据于2025-07-09公开中

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