2HFS
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2GZL
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![BU of 2gzl by Molmil](/molmil-images/mine/2gzl) | Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 5'-O-{[({[2-({[5-(DIMETHYLAMINO)NAPHTHALEN-1-YL]SULFONYL}AMINO)ETHYL]OXY}PHOSPHINATO)OXY]PHOSPHINATO}CYT, GERANYL DIPHOSPHATE, ... | Authors: | Crane, C.M, Kaiser, J, Ramsden, N.L, Lauw, S, Rohdich, F, Wolfgang, E, Hunter, W.N, Bacher, A, Diederich, F. | Deposit date: | 2006-05-11 | Release date: | 2006-11-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Fluorescent Inhibitors for Ispf, an Enzyme in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy. Angew.Chem.Int.Ed.Engl., 45, 2006
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2JG1
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![BU of 2jg1 by Molmil](/molmil-images/mine/2jg1) | STRUCTURE OF Staphylococcus aureus D-TAGATOSE-6-PHOSPHATE KINASE with cofactor and substrate | Descriptor: | 6-O-phosphono-beta-D-tagatofuranose, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Miallau, L, Hunter, W.N, McSweeney, S.M, Leonard, G.A. | Deposit date: | 2007-02-07 | Release date: | 2007-04-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Staphylococcus Aureus D-Tagatose-6-Phosphate Kinase Implicate Domain Motions in Specificity and Mechanism. J.Biol.Chem., 282, 2007
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2HK2
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2JGV
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![BU of 2jgv by Molmil](/molmil-images/mine/2jgv) | STRUCTURE OF Staphylococcus aureus D-TAGATOSE-6-PHOSPHATE KINASE in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, TAGATOSE-6-PHOSPHATE KINASE | Authors: | Miallau, L, Hunter, W.N, McSweeney, S.M, Leonard, G.A. | Deposit date: | 2007-02-16 | Release date: | 2007-04-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Staphylococcus Aureus D-Tagatose-6-Phosphate Kinase Implicate Domain Motions in Specificity and Mechanism. J.Biol.Chem., 282, 2007
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1OKG
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![BU of 1okg by Molmil](/molmil-images/mine/1okg) | 3-mercaptopyruvate sulfurtransferase from Leishmania major | Descriptor: | CALCIUM ION, POSSIBLE 3-MERCAPTOPYRUVATE SULFURTRANSFERASE, SULFITE ION | Authors: | Alphey, M.S, Hunter, W.N. | Deposit date: | 2003-07-24 | Release date: | 2003-09-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of Leishmania Major 3-Mercaptopyruvate Sulfurtransferase: A Three-Domain Architecture with a Serine Protease-Like Triad at the Active Site J.Biol.Chem., 278, 2003
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1OJ4
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![BU of 1oj4 by Molmil](/molmil-images/mine/1oj4) | Ternary complex of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | Descriptor: | 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLORIDE ION, ... | Authors: | Miallau, L, Alphey, M.S, Hunter, W.N. | Deposit date: | 2003-06-30 | Release date: | 2003-07-31 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase Proc.Natl.Acad.Sci.USA, 100, 2003
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1O73
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![BU of 1o73 by Molmil](/molmil-images/mine/1o73) | Tryparedoxin from Trypanosoma brucei | Descriptor: | TRYPAREDOXIN | Authors: | Gabrielsen, M, Alphey, M.S, Bond, C.S, Hunter, W.N. | Deposit date: | 2002-10-23 | Release date: | 2003-04-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
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1OC8
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![BU of 1oc8 by Molmil](/molmil-images/mine/1oc8) | TRYPAREDOXIN II FROM C.FASCICULATA SOLVED BY MR | Descriptor: | SULFATE ION, TRYPAREDOXIN II | Authors: | Leonard, G.A, Micossi, E, Hunter, W.N. | Deposit date: | 2003-02-07 | Release date: | 2003-04-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
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1O7L
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1NP6
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![BU of 1np6 by Molmil](/molmil-images/mine/1np6) | Crystal structure of Escherichia coli MobB | Descriptor: | Molybdopterin-guanine dinucleotide biosynthesis protein B, SULFATE ION | Authors: | McLuskey, K, Harrison, J.A, Schuttelkopf, A.W, Boxer, D.H, Hunter, W.N. | Deposit date: | 2003-01-17 | Release date: | 2003-04-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insight into the role of Escherichia coli MobB in Molybdenum cofactor biosynthesis based on the high resolution crystal structure J.Biol.Chem., 278, 2003
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1OC9
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![BU of 1oc9 by Molmil](/molmil-images/mine/1oc9) | TRYPAREDOXIN II FROM C.FASCICULATA solved by MR | Descriptor: | TRYPAREDOXIN II | Authors: | Leonard, G.A, Micossi, E, Hunter, W.N. | Deposit date: | 2003-02-07 | Release date: | 2003-03-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
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1O6J
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![BU of 1o6j by Molmil](/molmil-images/mine/1o6j) | Tryparedoxin II from C.fasciculata solved by sulphur phasing | Descriptor: | TRYPAREDOXIN II | Authors: | Leonard, G.A, Micossi, E, Hunter, W.N. | Deposit date: | 2002-10-04 | Release date: | 2002-11-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | De Novo Phasing of Two Crystal Forms of Tryparedoxin II Using the Anomalous Scattering from S Atoms: A Combination of Small Signal and Medium Resolution Reveals This to be a General Tool for Solving Protein Crystal Structures Acta Crystallogr.,Sect.D, 58, 2002
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1QK8
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1O81
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![BU of 1o81 by Molmil](/molmil-images/mine/1o81) | Tryparedoxin II from C.fasciculata solved by sulphur phasing | Descriptor: | SULFATE ION, TRYPAREDOXIN II | Authors: | Leonard, G.A, Micossi, E, Hunter, W.N. | Deposit date: | 2002-11-21 | Release date: | 2002-12-19 | Last modified: | 2019-10-09 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | De Novo Phasing of Two Crystal Forms of Tryparedoxin II Using the Anomalous Scattering from S Atoms: A Combination of Small Signal and Medium Resolution Reveals This to be a General Tool for Solving Protein Crystal Structures Acta Crystallogr.,Sect.D, 58, 2002
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1QNH
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1QNG
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3ZFI
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![BU of 3zfi by Molmil](/molmil-images/mine/3zfi) | Rap1a protein (SMA2260) from Serratia marcescens | Descriptor: | RAP1A PROTEIN | Authors: | Srikannathasan, V, O'Rourke, P.E.F, Rao, V.A, English, G, Coulthurst, S.J, Hunter, W.N. | Deposit date: | 2012-12-11 | Release date: | 2013-06-19 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural Basis for Type Vi Secreted Peptidoglycan Dl-Endopeptidase Function, Specificity and Neutralization in Serratia Marcescens Acta Crystallogr.,Sect.D, 69, 2013
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3ZFH
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![BU of 3zfh by Molmil](/molmil-images/mine/3zfh) | Crystal structure of Pseudomonas aeruginosa inosine 5'-monophosphate dehydrogenase | Descriptor: | CHLORIDE ION, INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE | Authors: | Rao, V.A, Shepherd, S.M, Owen, R, Hunter, W.N. | Deposit date: | 2012-12-11 | Release date: | 2013-01-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of Pseudomonas Aeruginosa Inosine 5'-Monophosphate Dehydrogenase Acta Crystallogr.,Sect.F, 69, 2013
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4ANO
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![BU of 4ano by Molmil](/molmil-images/mine/4ano) | Crystal Structure Geobacillus thermodenitrificans EssB cytoplasmic fragment | Descriptor: | CHLORIDE ION, ESSB, SODIUM ION | Authors: | Zoltner, M, Fyfe, P, Hunter, W.N. | Deposit date: | 2012-03-21 | Release date: | 2012-12-05 | Last modified: | 2013-11-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Architecture of Essb, an Integral Membrane Component of the Type Vii Secretion System. Structure, 21, 2013
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4A1R
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![BU of 4a1r by Molmil](/molmil-images/mine/4a1r) | The Structure of Serratia marcescens Lip, a membrane bound component of the Type VI Secretion System. | Descriptor: | 1,2-ETHANEDIOL, LIP, SODIUM ION | Authors: | Rao, V.A, Shepherd, S.M, English, G, Coulthurst, S.J, Hunter, W.N. | Deposit date: | 2011-09-19 | Release date: | 2011-10-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | The Structure of Serratia Marcescens Lip, a Membrane-Bound Component of the Type Vi Secretion System Acta Crystallogr.,Sect.F, 67, 2011
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4AGS
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![BU of 4ags by Molmil](/molmil-images/mine/4ags) | Leishmania TDR1 - a unique trimeric glutathione transferase | Descriptor: | 1,2-ETHANEDIOL, GLUTATHIONE, THIOL-DEPENDENT REDUCTASE 1 | Authors: | Fyfe, P.K, Westrop, G.D, Silva, A.M, Coombs, G.H, Hunter, W.N. | Deposit date: | 2012-01-31 | Release date: | 2012-07-04 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Leishmania Tdr1 Structure, a Unique Trimeric Glutathione Transferase Capable of Deglutathionylation and Antimonial Prodrug Activation. Proc.Natl.Acad.Sci.USA, 109, 2012
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4A5O
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![BU of 4a5o by Molmil](/molmil-images/mine/4a5o) | Crystal structure of Pseudomonas aeruginosa N5, N10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) | Descriptor: | BIFUNCTIONAL PROTEIN FOLD, DI(HYDROXYETHYL)ETHER, GLYCEROL | Authors: | Eadsforth, T.C, Gardiner, M, Maluf, F.V, McElroy, S, James, D, Frearson, J, Gray, D, Hunter, W.N. | Deposit date: | 2011-10-26 | Release date: | 2011-11-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Assessment of Pseudomonas Aeruginosa N(5),N(10)-Methylenetetrahydrofolate Dehydrogenase - Cyclohydrolase as a Potential Antibacterial Drug Target. Plos One, 7, 2012
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4A26
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![BU of 4a26 by Molmil](/molmil-images/mine/4a26) | The crystal structure of Leishmania major N5,N10- methylenetetrahydrofolate dehydrogenase/cyclohydrolase | Descriptor: | CHLORIDE ION, PUTATIVE C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC | Authors: | Eadsforth, T.C, Cameron, S, Hunter, W.N. | Deposit date: | 2011-09-22 | Release date: | 2011-10-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Crystal Structure of Leishmania Major N(5),N(10)-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase and Assessment of a Potential Drug Target. Mol.Biochem.Parasitol., 181, 2012
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4AX2
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![BU of 4ax2 by Molmil](/molmil-images/mine/4ax2) | New Type VI-secreted toxins and self-resistance proteins in Serratia marcescens | Descriptor: | 1,2-ETHANEDIOL, IODIDE ION, RAP1B | Authors: | English, G, Trunk, K, Rao, V.A, Srikannathasan, V, Fritsch, M.J, Guo, M, Hunter, W.N, Coulthurst, S.J. | Deposit date: | 2012-06-07 | Release date: | 2012-09-19 | Last modified: | 2013-07-17 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | New Secreted Toxins and Immunity Proteins Encoded within the Type Vi Secretion System Gene Cluster of Serratia Marcescens Mol.Microbiol., 86, 2012
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