4C83
| Crystal Structure of the IgG2a LPT3 in complex with an 8-sugar inner core analogue of Neisseria meningitidis | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-[beta-D-glucopyranose-(1-4)]L-glycero-alpha-D-manno-heptopyranose-(1-5)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, LPT3 HEAVY CHAIN, LPT3 LIGHT CHAIN, ... | Authors: | Parker, M.J, Gomery, K, Richard, G, Mackenzie, C.R, Cox, A.D, Richards, J.C, Evans, S.V. | Deposit date: | 2013-09-29 | Release date: | 2014-02-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Structural Basis for Selective Cross-Reactivity in a Bactericidal Antibody Against Inner Core Lipooligosaccharide from Neisseria Meningitidis. Glycobiology, 24, 2014
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3OKE
| Crystal structure of S25-39 in complex with Ko | Descriptor: | S25-39 Fab (IgG1k) heavy chain, S25-39 Fab (IgG1k) light chain, ZINC ION, ... | Authors: | Blackler, R.J, Evans, S.V. | Deposit date: | 2010-08-24 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity. Biochemistry, 50, 2011
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3OKM
| Crystal structure of unliganded S25-39 | Descriptor: | S25-39 Fab (IgG1k) heavy chain, S25-39 Fab (IgG1k) light chain | Authors: | Blackler, R.J, Evans, S.V. | Deposit date: | 2010-08-25 | Release date: | 2011-04-06 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity. Biochemistry, 50, 2011
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3OKN
| Crystal structure of S25-39 in complex with Kdo(2.4)Kdo(2.4)Kdo | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, S25-39 Fab (IgG1k) heavy chain, S25-39 Fab (IgG1k) light chain, ... | Authors: | Blackler, R.J, Evans, S.V. | Deposit date: | 2010-08-25 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity. Biochemistry, 50, 2011
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3OKK
| Crystal structure of S25-39 in complex with Kdo(2.4)Kdo | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, S25-39 Fab (IgG1k) heavy chain, S25-39 Fab (IgG1k) light chain, ... | Authors: | Blackler, R.J, Evans, S.V. | Deposit date: | 2010-08-25 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity. Biochemistry, 50, 2011
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3OKD
| Crystal structure of S25-39 in complex with Kdo | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, DI(HYDROXYETHYL)ETHER, S25-39 Fab (IgG1k) heavy chain, ... | Authors: | Blackler, R.J, Evans, S.V. | Deposit date: | 2010-08-24 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity. Biochemistry, 50, 2011
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3OKL
| Crystal structure of S25-39 in complex with Kdo(2.8)Kdo | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, S25-39 Fab (IgG1k) heavy chain, S25-39 Fab (IgG1k) light chain, ... | Authors: | Blackler, R.J, Evans, S.V. | Deposit date: | 2010-08-25 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity. Biochemistry, 50, 2011
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3OKO
| Crystal structure of S25-39 in complex with Kdo(2.8)Kdo(2.4)Kdo | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, S25-39 Fab (IgG1k) heavy chain, S25-39 Fab (IgG1k) light chain, ... | Authors: | Blackler, R.J, Evans, S.V. | Deposit date: | 2010-08-25 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity. Biochemistry, 50, 2011
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4RZC
| Fv M6P-1 in complex with mannose-6-phosphate | Descriptor: | 6-O-phosphono-alpha-D-mannopyranose, Fv M6P-1 heavy chain, Fv M6P-1 light chain, ... | Authors: | Blackler, R.J, Evans, D.W, Evans, S.V, Muller-Loennies, S. | Deposit date: | 2014-12-19 | Release date: | 2015-11-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.723 Å) | Cite: | Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner. Glycobiology, 26, 2016
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4FRA
| Crystal Structure of ABBA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant | Descriptor: | DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V. | Deposit date: | 2012-06-26 | Release date: | 2013-12-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24, 2014
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4FRE
| Crystal Structure of BBBB+UDP+Gal at pH 6.5 with MPD as the cryoprotectant | Descriptor: | DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V. | Deposit date: | 2012-06-26 | Release date: | 2013-12-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24, 2014
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4FRM
| Crystal Structure of BBBB+UDP+Gal at pH 7.0 with MPD as the cryoprotectant | Descriptor: | Histo-blood group ABO system transferase, URIDINE-5'-DIPHOSPHATE, beta-D-galactopyranose | Authors: | Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V. | Deposit date: | 2012-06-26 | Release date: | 2013-12-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24, 2014
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4GBP
| Crystal Structure of BBBB+UDP+Gal at pH 10 with MPD as the cryoprotectant | Descriptor: | Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V. | Deposit date: | 2012-07-27 | Release date: | 2013-12-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24, 2014
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4HGW
| Crystal structure of S25-2 in complex with a 5,6-dehydro-Kdo disaccharide | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3,5-dideoxy-alpha-D-threo-oct-5-en-2-ulopyranosidonic acid, Antibody Fab fragment, heavy chain, ... | Authors: | Brooks, C.L, Evans, S.V. | Deposit date: | 2012-10-08 | Release date: | 2013-01-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide. Acta Crystallogr.,Sect.F, 69, 2013
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3V0W
| Crystal structure of Fab WN1 222-5 in complex with LPS | Descriptor: | 2-amino-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-[alpha-D-galactopyranose-(1-6)]alpha-D-glucopyranose-(1-3)-[L-glycero-alpha-D-manno-heptopyranose-(1-7)]4-O-phosphono-L-glycero-alpha-D-manno-heptopyranose-(1-3)-4-O-phosphono-L-glycero-alpha-D-manno-heptopyranose-(1-5)-[3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)]3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, SULFATE ION, WN1 222-5 Fab (IgG2a) heavy chain, ... | Authors: | Gomery, K, Evans, S.V. | Deposit date: | 2011-12-08 | Release date: | 2012-12-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS. Proc.Natl.Acad.Sci.USA, 109, 2012
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3V0V
| Fab WN1 222-5 unliganded | Descriptor: | WN1 222-5 Fab (IgG2a) heavy chain, WN1 222-5 Fab (IgG2a) light chain | Authors: | Gomery, K, Evans, S.V. | Deposit date: | 2011-12-08 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS. Proc.Natl.Acad.Sci.USA, 109, 2012
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4HXB
| Crystal structure of 6B9 FAB | Descriptor: | 6B9 FAB HEAVY CHAIN, 6B9 FAB LIGHT CHAIN, CALCIUM ION | Authors: | Johal, A.R, Jarrell, H.C, Khieu, N.H, Letts, J.A, Landry, R.C, Jachymek, W, Yang, Q, Jennings, H.J, Brisson, J.R, Evans, S.V. | Deposit date: | 2012-11-09 | Release date: | 2013-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The antigen-binding site of an N-propionylated polysialic acid-specific antibody protective against group B meningococci is consistent with extended epitopes. Glycobiology, 23, 2013
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4HXA
| Crystal structure of 13D9 FAB | Descriptor: | 13D9 FAB HEAVY CHAIN, 13D9 FAB LIGHT CHAIN | Authors: | Johal, A.R, Jarrell, H.C, Khieu, N.H, Letts, J.A, Landry, R.C, Jachymek, W, Yang, Q, Jennings, H.J, Brisson, J.R, Evans, S.V. | Deposit date: | 2012-11-09 | Release date: | 2013-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | The antigen-binding site of an N-propionylated polysialic acid-specific antibody protective against group B meningococci is consistent with extended epitopes. Glycobiology, 23, 2013
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4FRH
| Crystal Structure of BBBB+UDP+Gal at pH 7.5 with MPD as the cryoprotectant | Descriptor: | DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V. | Deposit date: | 2012-06-26 | Release date: | 2013-12-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24, 2014
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4FRQ
| Crystal Structure of BBBB+UDP+Gal at pH 9.5 with MPD as the cryoprotectant | Descriptor: | DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V. | Deposit date: | 2012-06-26 | Release date: | 2013-12-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24, 2014
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4FRP
| Crystal Structure of BBBB+UDP+Gal at pH 8.5 with MPD as the cryoprotectant | Descriptor: | Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V. | Deposit date: | 2012-06-26 | Release date: | 2013-12-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24, 2014
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3PHO
| Crystal structure of S64-4 in complex with PSBP | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose, S64-4 Fab (IgG1) heavy chain, S64-4 Fab (IgG1) light chain | Authors: | Evans, D.W, Evans, S.V. | Deposit date: | 2010-11-04 | Release date: | 2011-05-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia. Glycobiology, 21, 2011
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3PHQ
| Crystal structure of S64-4 in complex with KDO | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, S64-4 Fab (IgG1) heavy chain, S64-4 Fab (IgG1) light chain | Authors: | Evans, D.W, Evans, S.V. | Deposit date: | 2010-11-04 | Release date: | 2011-05-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia. Glycobiology, 21, 2011
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3DV4
| Crystal structure of SAG506-01, tetragonal, crystal 1 | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ... | Authors: | Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V. | Deposit date: | 2008-07-18 | Release date: | 2008-12-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments. Acta Crystallogr.,Sect.D, 64, 2008
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3DUU
| Crystal structure of SAG506-01, orthorhombic, twinned, crystal 2 | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ... | Authors: | Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V. | Deposit date: | 2008-07-17 | Release date: | 2008-12-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments. Acta Crystallogr.,Sect.D, 64, 2008
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