4FRM

Crystal Structure of BBBB+UDP+Gal at pH 7.0 with MPD as the cryoprotectant

Summary for 4FRM

Entry DOI	10.2210/pdb4frm/pdb
Related	4FQW 4FRA 4FRB 4FRD 4FRE 4FRH 4FRL 4FRO 4FRP 4FRQ
Descriptor	Histo-blood group ABO system transferase, URIDINE-5'-DIPHOSPHATE, beta-D-galactopyranose, ... (4 entities in total)
Functional Keywords	manganese, abo rossmann fold, retaining glycosyltransferase, glycoprotein, blood group antigen, metal-binding, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	34632.58
Authors	Johal, A.R.,Alfaro, J.A.,Blackler, R.J.,Schuman, B.,Borisova, S.N.,Evans, S.V. (deposition date: 2012-06-26, release date: 2013-12-25, Last modification date: 2023-09-13)
Primary citation	Johal, A.R.,Blackler, R.J.,Alfaro, J.A.,Schuman, B.,Borisova, S.,Evans, S.V. pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24:237-246, 2014 Cited by PubMed: 24265507 DOI: 10.1093/glycob/cwt098 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation