4HVA
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5GHA
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![BU of 5gha by Molmil](/molmil-images/mine/5gha) | Sulfur Transferase TtuA in complex with Sulfur Carrier TtuB | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Sulfur Carrier TtuB, ... | Authors: | Chen, M, Narai, S, Tanaka, Y, Yao, M. | Deposit date: | 2016-06-19 | Release date: | 2017-05-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Biochemical and structural characterization of oxygen-sensitive 2-thiouridine synthesis catalyzed by an iron-sulfur protein TtuA Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5GV1
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![BU of 5gv1 by Molmil](/molmil-images/mine/5gv1) | Crystal structure of ENZbleach xylanase wild type | Descriptor: | Endo-1,4-beta-xylanase | Authors: | Chitnumsub, P, Jaruwat, A, Boonyapakorn, K, Noytanom, K. | Deposit date: | 2016-09-01 | Release date: | 2017-08-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure-based protein engineering for thermostable and alkaliphilic enhancement of endo-beta-1,4-xylanase for applications in pulp bleaching J. Biotechnol., 259, 2017
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2ZFU
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![BU of 2zfu by Molmil](/molmil-images/mine/2zfu) | Structure of the methyltransferase-like domain of nucleomethylin | Descriptor: | Cerebral protein 1, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Minami, H, Hashimoto, H, Murayama, A, Yanagisawa, J, Sato, M, Shimizu, T. | Deposit date: | 2008-01-14 | Release date: | 2008-12-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Epigenetic control of rDNA loci in response to intracellular energy status Cell(Cambridge,Mass.), 133, 2008
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6TMN
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![BU of 6tmn by Molmil](/molmil-images/mine/6tmn) | Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond | Descriptor: | CALCIUM ION, N-[(2R,4S)-4-hydroxy-2-(2-methylpropyl)-4-oxido-7-oxo-9-phenyl-3,8-dioxa-6-aza-4-phosphanonan-1-oyl]-L-leucine, THERMOLYSIN, ... | Authors: | Tronrud, D.E, Holden, H.M, Matthews, B.W. | Deposit date: | 1987-06-29 | Release date: | 1989-01-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond. Science, 235, 1987
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5IKU
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![BU of 5iku by Molmil](/molmil-images/mine/5iku) | Crystal structure of the Hathewaya histolytica ColG tandem collagen-binding domain s3as3b in the presence of calcium at 1.9 Angstrom resolution | Descriptor: | CALCIUM ION, Collagenase | Authors: | Janowska, K, Bauer, R, Roeser, R, Sakon, J, Matsushita, O. | Deposit date: | 2016-03-03 | Release date: | 2017-03-15 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ca2+-induced orientation of tandem collagen binding domains from clostridial collagenase ColG permits two opposing functions of collagen fibril formation and retardation. Febs J., 285, 2018
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3IIT
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![BU of 3iit by Molmil](/molmil-images/mine/3iit) | Factor XA in complex with a cis-1,2-diaminocyclohexane derivative | Descriptor: | 7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide, Activated factor Xa heavy chain, CALCIUM ION, ... | Authors: | Suzuki, M. | Deposit date: | 2009-08-03 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties. Bioorg.Med.Chem., 17, 2009
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7F8K
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7TLN
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![BU of 7tln by Molmil](/molmil-images/mine/7tln) | STRUCTURAL ANALYSIS OF THE INHIBITION OF THERMOLYSIN BY AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR | Descriptor: | 2-(ACETYL-HYDROXY-AMINO)-4-METHYL-PENTANOIC ACID METHYL ESTER, CALCIUM ION, THERMOLYSIN, ... | Authors: | Matthews, B.W, Holmes, M.A, Tronrud, D.E. | Deposit date: | 1983-01-27 | Release date: | 1983-03-09 | Last modified: | 2022-11-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor. Biochemistry, 22, 1983
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5GOW
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5YJ9
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![BU of 5yj9 by Molmil](/molmil-images/mine/5yj9) | Crystal structure of Tribolium castaneum PINK1 kinase domain in complex with AMP-PNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PINK1, ... | Authors: | Okatsu, K, Sato, Y, Fukai, S. | Deposit date: | 2017-10-09 | Release date: | 2018-07-25 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structural insights into ubiquitin phosphorylation by PINK1. Sci Rep, 8, 2018
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4ZY3
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![BU of 4zy3 by Molmil](/molmil-images/mine/4zy3) | Crystal Structure of Keap1 in Complex with a small chemical compound, K67 | Descriptor: | FORMIC ACID, Kelch-like ECH-associated protein 1, N,N'-[2-(2-oxopropyl)naphthalene-1,4-diyl]bis(4-ethoxybenzenesulfonamide) | Authors: | Fukutomi, T, Iso, T, Suzuki, T, Takagi, K, Mizushima, T, Komatsu, M, Yamamoto, M. | Deposit date: | 2015-05-21 | Release date: | 2016-05-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming Nat Commun, 7, 2016
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7X56
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![BU of 7x56 by Molmil](/molmil-images/mine/7x56) | A CBg-ParM filament with ADP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ParM/StbA family protein | Authors: | Koh, A, Ali, S, Robinson, R, Narita, A. | Deposit date: | 2022-03-04 | Release date: | 2023-03-08 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | A new actin-like filament from Clostridium botulinum exhibits a new system of filament turn over To Be Published
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7X54
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![BU of 7x54 by Molmil](/molmil-images/mine/7x54) | A CBg-ParM filament with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ParM/StbA family protein | Authors: | Koh, A, Ali, S, Robinson, R, Narita, A. | Deposit date: | 2022-03-04 | Release date: | 2023-03-08 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | A new actin-like filament from Clostridium botulinum exhibits a new system of filament turn over To Be Published
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7X59
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![BU of 7x59 by Molmil](/molmil-images/mine/7x59) | A CBg-ParM filament with GTP or GDPPi | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, ParM/StbA family protein | Authors: | Koh, A, Ali, S, Robinson, R, Narita, A. | Deposit date: | 2022-03-04 | Release date: | 2023-03-08 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | A new actin-like filament from Clostridium botulinum exhibits a new system of filament turn over To Be Published
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7X55
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6L93
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1LZ6
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![BU of 1lz6 by Molmil](/molmil-images/mine/1lz6) | STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, HUMAN LYSOZYME | Authors: | Matsushima, M, Inaka, K, Yamada, T, Sekiguchi, K, Kikuchi, M. | Deposit date: | 1993-02-03 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional analyses of the Arg-Gly-Asp sequence introduced into human lysozyme. J.Biol.Chem., 268, 1993
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7YCE
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![BU of 7yce by Molmil](/molmil-images/mine/7yce) | KRas G12C in complex with Compound 7b | Descriptor: | 1-[7-[6-chloranyl-2-(1-ethylpiperidin-4-yl)oxy-8-fluoranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]-2,7-diazaspiro[3.5]nonan-2-yl]propan-1-one, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | Authors: | Amano, Y. | Deposit date: | 2022-07-01 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery and biological evaluation of 1-{2,7-diazaspiro[3.5]nonan-2-yl}prop-2-en-1-one derivatives as covalent inhibitors of KRAS G12C with favorable metabolic stability and anti-tumor activity. Bioorg.Med.Chem., 71, 2022
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7YCC
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![BU of 7ycc by Molmil](/molmil-images/mine/7ycc) | KRas G12C in complex with Compound 5c | Descriptor: | 1-[7-[6-chloranyl-8-fluoranyl-7-(5-methyl-1~{H}-indazol-4-yl)-2-[(1-methylpiperidin-4-yl)amino]quinazolin-4-yl]-2,7-diazaspiro[3.5]nonan-2-yl]propan-1-one, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | Authors: | Amano, Y. | Deposit date: | 2022-07-01 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Discovery and biological evaluation of 1-{2,7-diazaspiro[3.5]nonan-2-yl}prop-2-en-1-one derivatives as covalent inhibitors of KRAS G12C with favorable metabolic stability and anti-tumor activity. Bioorg.Med.Chem., 71, 2022
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1LZ5
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![BU of 1lz5 by Molmil](/molmil-images/mine/1lz5) | STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, HUMAN LYSOZYME | Authors: | Matsushima, M, Inaka, K, Yamada, T, Sekiguchi, K, Kikuchi, M. | Deposit date: | 1993-02-03 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional analyses of the Arg-Gly-Asp sequence introduced into human lysozyme. J.Biol.Chem., 268, 1993
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3RGA
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![BU of 3rga by Molmil](/molmil-images/mine/3rga) | Crystal structure of epoxide hydrolase for polyether lasalocid A biosynthesis | Descriptor: | (4R,5S)-3-[(2R)-2-{(2S,2'R,4S,5S,5'R)-2,5'-diethyl-5'-[(1S)-1-hydroxyethyl]-4-methyloctahydro-2,2'-bifuran-5-yl}butanoyl]-4-methyl-5-phenyl-1,3-oxazolidin-2-one, (4R,5S)-3-[(2R,3S,4S)-2-ethyl-5-[(3R)-2-ethyl-3-[2-[(2R,3R)-2-ethyl-3-methyl-oxiran-2-yl]ethyl]oxiran-2-yl]-3-hydroxy-4-methyl-pentanoyl]-4-methyl-5-phenyl-1,3-oxazolidin-2-one, ACETATE ION, ... | Authors: | Hotta, K, Mathews, I.I, Chen, X, Kim, C.-Y. | Deposit date: | 2011-04-08 | Release date: | 2012-03-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis Nature, 483, 2012
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1V5W
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![BU of 1v5w by Molmil](/molmil-images/mine/1v5w) | Crystal structure of the human Dmc1 protein | Descriptor: | Meiotic recombination protein DMC1/LIM15 homolog | Authors: | Kinebuchi, T, Kagawa, W, Enomoto, R, Ikawa, S, Shibata, T, Kurumizaka, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-11-26 | Release date: | 2004-05-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for octameric ring formation and DNA interaction of the human homologous-pairing protein dmc1 Mol.Cell, 14, 2004
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7SUT
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![BU of 7sut by Molmil](/molmil-images/mine/7sut) | Light harvesting phycobiliprotein HaPE645 from the cryptophyte Hemiselmis andersenii CCMP644 | Descriptor: | (15,16)-DIHYDROBILIVERDIN (SINGLY LINKED), 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | Authors: | Rathbone, H.W, Michie, K.A, Laos, A.L, Curmi, P.M.G. | Deposit date: | 2021-11-18 | Release date: | 2023-10-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Molecular dissection of the soluble photosynthetic antenna from the cryptophyte alga Hemiselmis andersenii. Commun Biol, 6, 2023
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3CTS
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