1N7J
| The structure of Phenylethanolamine N-methyltransferase in complex with S-adenosylhomocysteine and an iodinated inhibitor | Descriptor: | 7-IODO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | McMillan, F.M, Archbold, J, McLeish, M.J, Caine, J.M, Criscione, K.R, Grunewald, G.L, Martin, J.L. | Deposit date: | 2002-11-15 | Release date: | 2003-12-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular recognition of sub-micromolar inhibitors by the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase. J.Med.Chem., 47, 2004
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1NOT
| THE 1.2 ANGSTROM STRUCTURE OF G1 ALPHA CONOTOXIN | Descriptor: | GI ALPHA CONOTOXIN | Authors: | Guddat, L.W, Shan, L, Martin, J.L, Edmundson, A.B, Gray, W.R. | Deposit date: | 1996-05-02 | Release date: | 1996-12-07 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Three-dimensional structure of the alpha-conotoxin GI at 1.2 A resolution Biochemistry, 35, 1996
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1MTR
| HIV-1 PROTEASE COMPLEXED WITH A CYCLIC PHE-ILE-VAL PEPTIDOMIMETIC INHIBITOR | Descriptor: | HIV-1 PROTEASE, SULFATE ION, [1-BENZYL-3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YLAMINO)-2-HYDROXY-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER | Authors: | Wickramasinghe, W, Begun, J, Martin, J.L. | Deposit date: | 1996-02-15 | Release date: | 1996-08-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode. J.Am.Chem.Soc., 118, 1996
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2Y92
| Crystal structure of MAL adaptor protein | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN, | Authors: | Valkov, E, Stamp, A, Martin, J.L, Kobe, B. | Deposit date: | 2011-02-11 | Release date: | 2011-09-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Crystal Structure of Toll-Like Receptor Adaptor Mal/Tirap Reveals the Molecular Basis for Signal Transduction and Disease Protection. Proc.Natl.Acad.Sci.USA, 108, 2011
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4K6X
| Crystal structure of disulfide oxidoreductase from Mycobacterium tuberculosis | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Disulfide oxidoreductase | Authors: | Premkumar, L, Martin, J.L. | Deposit date: | 2013-04-16 | Release date: | 2013-10-02 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.972 Å) | Cite: | Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases. Acta Crystallogr.,Sect.D, 69, 2013
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4MCU
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4MLY
| Disulfide isomerase from multidrug resistance IncA/C related integrative and conjugative elements in oxidized state (P21 space group) | Descriptor: | 1,3-BUTANEDIOL, DsbP | Authors: | Premkumar, L, Kurth, F, Neyer, S, Martin, J.L. | Deposit date: | 2013-09-06 | Release date: | 2013-12-11 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.207 Å) | Cite: | The Multidrug Resistance IncA/C Transferable Plasmid Encodes a Novel Domain-swapped Dimeric Protein-disulfide Isomerase. J.Biol.Chem., 289, 2014
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4ML6
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4ML1
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3AX4
| Three-dimensional structure of lectin from Dioclea violacea and comparative vasorelaxant effects with Dioclea rostrata | Descriptor: | 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, MANGANESE (II) ION, ... | Authors: | Bezerra, M.J.B, Bezerra, G.A, Martins, J.L, Nascimento, K.S, Nagano, C.S, Gruber, K, Assereuy, A.M, Delatorre, P, Rocha, B.A.M, Cavada, B.S. | Deposit date: | 2011-03-29 | Release date: | 2012-04-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.613 Å) | Cite: | Crystal structure of Dioclea violacea lectin and a comparative study of vasorelaxant properties with Dioclea rostrata lectin Int.J.Biochem.Cell Biol., 45, 2013
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3BCK
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3BD2
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2H0I
| Crystal Structure of DsbG V216M mutant | Descriptor: | SULFATE ION, Thiol:disulfide interchange protein dsbG | Authors: | Hiniker, A, Heras, B, Martin, J.L, Stuckey, J, Bardwell, J.C.A. | Deposit date: | 2006-05-15 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Short-circuiting divergent evolution: laboratory evolution of one disulfide isomerase to resemble another To be Published
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2H0H
| Crystal Structure of DsbG K113E mutant | Descriptor: | SULFATE ION, Thiol:disulfide interchange protein dsbG | Authors: | Hiniker, A, Heras, B, Martin, J.L, Stuckey, J, Bardwell, J.C.A. | Deposit date: | 2006-05-15 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Short-circuiting divergent evolution: laboratory evolution of one disulfide isomerase to resemble another To be Published
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2H0G
| Crystal Structure of DsbG T200M mutant | Descriptor: | SULFATE ION, Thiol:disulfide interchange protein dsbG | Authors: | Hiniker, A, Heras, B, Martin, J.L, Stuckey, J, Bardwell, J.C.A. | Deposit date: | 2006-05-15 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Short-circuiting divergent evolution: laboratory evolution of one disulfide isomerase to resemble another To be Published
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1UTE
| PIG PURPLE ACID PHOSPHATASE COMPLEXED WITH PHOSPHATE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ISOPROPYL ALCOHOL, MU-OXO-DIIRON, ... | Authors: | Guddat, L.W, Mcalpine, A, Hume, D, Hamilton, S, De Jersey, J, Martin, J.L. | Deposit date: | 1999-01-18 | Release date: | 1999-10-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of mammalian purple acid phosphatase. Structure Fold.Des., 7, 1999
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3PUJ
| Crystal structure of the MUNC18-1 and SYNTAXIN4 N-Peptide complex | Descriptor: | Syntaxin-4 N-terminal peptide, Syntaxin-binding protein 1 | Authors: | Hu, S.-H, Christie, M.P, Saez, N.J, Latham, C.F, Jarrott, R, Lua, L.H.L, Collins, B.M, Martin, J.L. | Deposit date: | 2010-12-05 | Release date: | 2011-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.313 Å) | Cite: | Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation Proc.Natl.Acad.Sci.USA, 108, 2011
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7RGV
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4DVC
| Structural and functional studies of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera toxin production | Descriptor: | DIMETHYL SULFOXIDE, SULFATE ION, Thiol:disulfide interchange protein DsbA | Authors: | Walden, P.M, Martin, J.L. | Deposit date: | 2012-02-23 | Release date: | 2012-10-31 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The 1.2 A resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production Acta Crystallogr.,Sect.D, 68, 2012
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4OCF
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4OCE
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4P3Y
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4OD7
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4TKY
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2G71
| Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy | Descriptor: | (3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE, GLYCEROL, Phenylethanolamine N-methyltransferase, ... | Authors: | Tyndall, J.D.A, Gee, C.L, Martin, J.L. | Deposit date: | 2006-02-27 | Release date: | 2007-02-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Enzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase J.Med.Chem., 50, 2007
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