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234D
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BU of 234d by Molmil
CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK
Descriptor: 3'-DESAMINO-3'-(2-METHOXY-4-MORPHOLINYL)-DOXORUBICIN, DNA (5'-D(*CP*GP*AP*TP*CP*G)-3')
Authors:Gao, Y.-G, Wang, A.H.-J.
Deposit date:1995-06-22
Release date:1996-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink.
J.Biomol.Struct.Dyn., 13, 1995
288D
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BU of 288d by Molmil
SUBSTITUTIONS AT C2' OF DAUNOSAMINE IN THE ANTICANCER DAUNORUBICIN ALTER ITS DNA-BINDING SEQUENCE SPECIFICITY
Descriptor: 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3')
Authors:Gao, Y.-G, Priebe, W, Wang, A.H.-J.
Deposit date:1996-07-22
Release date:1996-09-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Substitutions at C2' of daunosamine in the anticancer drug daunorubicin alter its DNA-binding sequence specificity.
Eur.J.Biochem., 240, 1996
236D
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BU of 236d by Molmil
CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK
Descriptor: 3'-DESAMINO-3'-(3-CYANO-4-MORPHOLINYL)-DOXORUBICIN, DNA (5'-D(*CP*GP*AP*TP*CP*G)-3')
Authors:Gao, Y.-G, Wang, A.H.-J.
Deposit date:1995-06-22
Release date:1996-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink.
J.Biomol.Struct.Dyn., 13, 1995
215D
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BU of 215d by Molmil
CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK
Descriptor: 3'-DESAMINO-3'-(2-METHOXY-4-MORPHOLINYL)-DOXORUBICIN, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3')
Authors:Gao, Y.-G, Wang, A.H.-J.
Deposit date:1995-06-22
Release date:1996-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink.
J.Biomol.Struct.Dyn., 13, 1995
277D
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BU of 277d by Molmil
SUBSTITUTIONS AT C2' OF DAUNOSAMINE IN THE ANTICANCER DAUNORUBICIN ALTER ITS DNA-BINDING SEQUENCE SPECIFICITY
Descriptor: 2'-BROMO-4'-EPIDAUNORUBICIN, 5'-D(*CP*GP*CP*(G49)P*CP*G)-3'
Authors:Gao, Y.-G, Priebe, W, Wang, A.H.-J.
Deposit date:1996-07-22
Release date:1996-09-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Substitutions at C2' of daunosamine in the anticancer drug daunorubicin alter its DNA-binding sequence specificity.
Eur.J.Biochem., 240, 1996
440D
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BU of 440d by Molmil
HIGH RESOLUTION A-DNA CRYSTAL STRYCTURES OF D(AGGGGCCCCT): AN A-DNA MODEL OF POLY(DG).POLY(DC)
Descriptor: DNA (5'-D(*AP*GP*GP*GP*GP*CP*CP*CP*CP*T)-3')
Authors:Gao, Y.-G, Robinson, H.H, Wang, A.H.-J.
Deposit date:1999-01-13
Release date:1999-01-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:High-resolution A-DNA crystal structures of d(AGGGGCCCCT). An A-DNA model of poly(dG) x poly(dC).
Eur.J.Biochem., 261, 1999
1D36
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BU of 1d36 by Molmil
FACILE FORMATION OF A CROSSLINKED ADDUCT BETWEEN DNA AND THE DAUNORUBICIN DERIVATIVE MAR70 MEDIATED BY FORMALDEHYDE: MOLECULAR STRUCTURE OF THE MAR70-D(CGTNACG) COVALENT ADDUC
Descriptor: 4'-EPI-4'-(2-DEOXYFUCOSE)DAUNOMYCIN, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), MAGNESIUM ION
Authors:Gao, Y.-G, Liaw, Y.-C, Li, Y.-K, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J.
Deposit date:1991-04-23
Release date:1992-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct.
Proc.Natl.Acad.Sci.USA, 88, 1991
1D22
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BU of 1d22 by Molmil
BINDING OF THE ANTITUMOR DRUG NOGALAMYCIN AND ITS DERIVATIVES TO DNA: STRUCTURAL COMPARISON
Descriptor: DNA (5'-D(*(5CM)P*GP*TP*(AS)P*(5CM)P*G)-3'), U-58872, HYDROXY DERIVATIVE OF NOGALAMYCIN
Authors:Gao, Y.-G, Liaw, Y.-C, Robinson, H, Wang, A.H.-J.
Deposit date:1990-08-08
Release date:1991-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison.
Biochemistry, 29, 1990
1D38
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BU of 1d38 by Molmil
INFLUENCE OF AGLYCONE MODIFICATIONS ON THE BINDING OF ANTHRACYCLINE DRUGS TO DNA: THE MOLECULAR STRUCTURE OF IDARUBICIN AND 4-O-DEMETHYL-11-DEOXYDOXORUBICIN COMPLEXED TO D(CGATCG)
Descriptor: DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), IDARUBICIN, MAGNESIUM ION
Authors:Gao, Y.-G, Wang, A.H.-J.
Deposit date:1991-04-23
Release date:1992-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influence of aglycone modifications on the binding of anthracycline drugs to DNA: the molecular structure of idarubicin and 4-O-demethyl-11-deoxydoxorubicin complexed to d(CGATCG).
Anti-Cancer Drug Des., 6, 1991
1D21
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BU of 1d21 by Molmil
BINDING OF THE ANTITUMOR DRUG NOGALAMYCIN AND ITS DERIVATIVES TO DNA: STRUCTURAL COMPARISON
Descriptor: DNA (5'-D(*(5CM)P*GP*TP*(AS)P*(5CM)P*G)-3'), NOGALAMYCIN
Authors:Gao, Y.-G, Liaw, Y.-C, Robinson, H, Wang, A.H.-J.
Deposit date:1990-08-08
Release date:1991-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison.
Biochemistry, 29, 1990
1D37
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BU of 1d37 by Molmil
INFLUENCE OF AGLYCONE MODIFICATIONS ON THE BINDING OF ANTHRACYCLINE DRUGS TO DNA: THE MOLECULAR STRUCTURE OF IDARUBICIN AND 4-O-DEMETHYL-11-DEOXYDOXORUBICIN COMPLEXED TO D(CGATCG)
Descriptor: 1-O-DEMETHYL-6-DEOXYDOXORUBICIN, DNA (5'-D(*CP*GP*AP*TP*CP*G)-3')
Authors:Gao, Y.-G, Wang, A.H.-J.
Deposit date:1991-04-23
Release date:1992-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Influence of aglycone modifications on the binding of anthracycline drugs to DNA: the molecular structure of idarubicin and 4-O-demethyl-11-deoxydoxorubicin complexed to d(CGATCG).
Anti-Cancer Drug Des., 6, 1991
1D35
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BU of 1d35 by Molmil
FACILE FORMATION OF A CROSSLINKED ADDUCT BETWEEN DNA AND THE DAUNORUBICIN DERIVATIVE MAR70 MEDIATED BY FORMALDEHYDE: MOLECULAR STRUCTURE OF THE MAR70-D(CGTNACG) COVALENT ADDUC
Descriptor: 4'-EPI-4'-(2-DEOXYFUCOSE)DAUNOMYCIN, DNA (5'-D(*CP*GP*TP*(A40)P*CP*G)-3'), MAGNESIUM ION
Authors:Gao, Y.-G, Liaw, Y.-C, Li, Y.-K, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J.
Deposit date:1991-04-23
Release date:1992-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct.
Proc.Natl.Acad.Sci.USA, 88, 1991
1VGJ
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BU of 1vgj by Molmil
Crystal structure of 2'-5' RNA ligase from Pyrococcus horikoshii
Descriptor: Hypothetical protein PH0099
Authors:Yao, M, Morita, H, Okada, A, Tanaka, I.
Deposit date:2004-04-27
Release date:2005-06-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The structure of Pyrococcus horikoshii 2'-5' RNA ligase at 1.94 A resolution reveals a possible open form with a wider active-site cleft
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2E8G
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BU of 2e8g by Molmil
The structure of protein from P. horikoshii at 1.7 angstrom resolution
Descriptor: Hypothetical protein PH0536
Authors:Gao, Y.G, Yao, M, Tanaka, I.
Deposit date:2007-01-19
Release date:2008-01-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of protein PH0536 from Pyrococcus horikoshii at 1.7 A resolution reveals a novel assembly of an oligonucleotide/oligosaccharide-binding fold and an alpha-helical bundle
Proteins, 71, 2008
144D
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BU of 144d by Molmil
MINOR GROOVE BINDING OF SN6999 TO AN ALKYLATED DNA: MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG)-SN6999 COMPLEX
Descriptor: 1-METHYL-4-[4-[4-(4-(1-METHYLQUINOLINIUM)AMINO)BENZAMIDO]ANILINO]PYRIDINIUM, DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Gao, Y.-G, Sriram, M, Denny, W.A, Wang, A.H.-J.
Deposit date:1993-10-26
Release date:1995-05-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Minor groove binding of SN6999 to an alkylated DNA: molecular structure of d(CGC[e6G]AATTCGCG)-SN6999 complex.
Biochemistry, 32, 1993
1BF4
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BU of 1bf4 by Molmil
CHROMOSOMAL DNA-BINDING PROTEIN SSO7D/D(GCGAACGC) COMPLEX
Descriptor: DNA (5'-D(*GP*CP*GP*AP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*5IUP*CP*GP*C)-3'), PROTEIN (CHROMOSOMAL PROTEIN SSO7D)
Authors:Su, S, Gao, Y.-G, Robinson, H, Padmanabhan, S, Lim, L, Shriver, J.W, Wang, A.H.-J.
Deposit date:1998-05-27
Release date:1999-11-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNA.
Nat.Struct.Biol., 5, 1998
1DCR
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BU of 1dcr by Molmil
CRYSTAL STRUCTURE OF DNA SHEARED TANDEM G-A BASE PAIRS
Descriptor: 5'-D(*CP*CP*GP*AP*AP*(BRU)P*GP*AP*GP*G)-3', MAGNESIUM ION, SODIUM ION, ...
Authors:Gao, Y.-G, Robinson, H, Sanishvili, R, Joachimiak, A, Wang, A.H.-J.
Deposit date:1999-11-05
Release date:1999-11-19
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution.
Biochemistry, 38, 1999
1BNZ
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BU of 1bnz by Molmil
SSO7D HYPERTHERMOPHILE PROTEIN/DNA COMPLEX
Descriptor: 5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3', DNA-BINDING PROTEIN 7A
Authors:Gao, Y.-G, Su, S.-Y, Robinson, H, Padmanabhan, S, Lim, L, Mccrary, B.S, Edmondos, S.P, Shrive, J.W, Wang, A.H.-J.
Deposit date:1998-07-31
Release date:1998-11-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNA.
Nat.Struct.Biol., 5, 1998
1D9R
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BU of 1d9r by Molmil
CRYSTAL STRUCTURE OF DNA SHEARED TANDEM G-A BASE PAIRS
Descriptor: 5'-D(*CP*CP*GP*AP*AP*(BRU)P*GP*AP*GP*G)-3', COBALT HEXAMMINE(III)
Authors:Gao, Y.-G, Robinson, H, Sanishvili, R, Joachimiak, A, Wang, A.H.-J.
Deposit date:1999-10-29
Release date:1999-11-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution.
Biochemistry, 38, 1999
1D8X
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BU of 1d8x by Molmil
CRYSTAL STRUCTURE OF DNA SHEARED TANDEM G A BASE PAIRS
Descriptor: 5'-D(*CP*CP*GP*AP*AP*TP*GP*AP*GP*G)-3', COBALT HEXAMMINE(III), MAGNESIUM ION
Authors:Gao, Y.-G, Robinson, H, Sanishvili, R, Joachimiak, A, Wang, A.H.-J.
Deposit date:1999-10-26
Release date:1999-11-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution.
Biochemistry, 38, 1999
3KZ3
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BU of 3kz3 by Molmil
A structure of a lambda repressor fragment mutant
Descriptor: Repressor protein CI
Authors:Gruebele, M, Liu, F, Gao, Y.
Deposit date:2009-12-07
Release date:2010-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:A survey of lambda repressor fragments from two-state to downhill folding.
J.Mol.Biol., 397, 2010
4V7J
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BU of 4v7j by Molmil
Structure of RelE nuclease bound to the 70S ribosome (precleavage state)
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E.
Deposit date:2009-11-02
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
1FDG
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BU of 1fdg by Molmil
BINDING OF A MACROCYCLIC BISACRIDINE AND AMETANTRONE TO CGTACG INVOLVES SIMILAR UNUSUAL INTERCALATION PLATFORMS (AMETANTRONE COMPLEX)
Descriptor: 1,4-BIS-[2-(2-HYDROXY-ETHYLAMINO)-ETHYLAMINO]-ANTHRAQUINONE, COBALT (II) ION, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), ...
Authors:Yang, X.-L, Robinson, H, Gao, Y.-G, Wang, A.H.-J.
Deposit date:2000-07-20
Release date:2000-08-07
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.
Biochemistry, 39, 2000
1FD5
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BU of 1fd5 by Molmil
BINDING OF A MACROCYCLIC BISACRIDINE AND AMETANTRONE TO CGTACG INVOLVES SIMILAR UNUSUAL INTERCALATION PLATFORMS (BISACRIDINE COMPLEX)
Descriptor: COBALT (II) ION, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), MACROCYCLIC-BIS-9-AMINO-ACRIDINE, ...
Authors:Yang, X.-L, Robinson, H, Gao, Y.-G, Wang, A.H.-J.
Deposit date:2000-07-19
Release date:2000-08-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.
Biochemistry, 39, 2000
1GKH
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BU of 1gkh by Molmil
MUTANT K69H OF GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN)
Descriptor: GENE V PROTEIN
Authors:Su, S, Gao, Y.-G, Zhang, H, Terwilliger, T.C, Wang, A.H.-J.
Deposit date:1997-03-04
Release date:1997-09-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography.
Protein Sci., 6, 1997

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