5T2G
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![BU of 5t2g by Molmil](/molmil-images/mine/5t2g) | mPI3Kd IN COMPLEX WITH 7i | Descriptor: | 4-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]pyrazole-1-carboxamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Authors: | Petersen, J, Terstige, I, Perry, M, Svensson, T, Tyrchan, C, Lindmark, H, Oster, L. | Deposit date: | 2016-08-23 | Release date: | 2017-04-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Discovery of triazole aminopyrazines as a highly potent and selective series of PI3K delta inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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1KK8
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![BU of 1kk8 by Molmil](/molmil-images/mine/1kk8) | SCALLOP MYOSIN (S1-ADP-BeFx) IN THE ACTIN-DETACHED CONFORMATION | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... | Authors: | Himmel, M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | Deposit date: | 2001-12-06 | Release date: | 2002-10-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc.Natl.Acad.Sci.USA, 99, 2002
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1NXK
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![BU of 1nxk by Molmil](/molmil-images/mine/1nxk) | Crystal structure of staurosporine bound to MAP KAP kinase 2 | Descriptor: | MAP kinase-activated protein kinase 2, STAUROSPORINE, SULFATE ION | Authors: | Underwood, K.W, Parris, K.D, Federico, E, Mosyak, L, Czerwinski, R.M, Shane, T, Taylor, M, Svenson, K, Liu, Y, Hsiao, C.L, Wolfrom, S, Malakian, K, Telliez, J.B, Lin, L.L, Kriz, R.W, Seehra, J, Somers, W.S, Stahl, M.L. | Deposit date: | 2003-02-10 | Release date: | 2003-10-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme Structure, 11, 2003
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1KO5
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![BU of 1ko5 by Molmil](/molmil-images/mine/1ko5) | Crystal structure of gluconate kinase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Gluconate kinase, MAGNESIUM ION | Authors: | Kraft, L, Sprenger, G.A, Lindqvist, Y. | Deposit date: | 2001-12-20 | Release date: | 2002-05-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Conformational changes during the catalytic cycle of gluconate kinase as revealed by X-ray crystallography. J.Mol.Biol., 318, 2002
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1KOJ
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![BU of 1koj by Molmil](/molmil-images/mine/1koj) | Crystal structure of rabbit phosphoglucose isomerase complexed with 5-phospho-D-arabinonohydroxamic acid | Descriptor: | 5-PHOSPHO-D-ARABINOHYDROXAMIC ACID, Glucose-6-phosphate isomerase | Authors: | Arsenieva, D, Hardre, R, Salmon, L, Jeffery, C.J. | Deposit date: | 2001-12-20 | Release date: | 2002-05-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of rabbit phosphoglucose isomerase complexed with 5-phospho-D-arabinonohydroxamic acid. Proc.Natl.Acad.Sci.USA, 99, 2002
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5T26
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![BU of 5t26 by Molmil](/molmil-images/mine/5t26) | Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, L(+)-TARTARIC ACID, ... | Authors: | Chooback, L, Thomas, L.M, Karsten, W.E, Fleming, C.D, Seabourn, P. | Deposit date: | 2016-08-23 | Release date: | 2016-10-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. To Be Published
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1KK7
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![BU of 1kk7 by Molmil](/molmil-images/mine/1kk7) | SCALLOP MYOSIN IN THE NEAR RIGOR CONFORMATION | Descriptor: | CALCIUM ION, MAGNESIUM ION, MYOSIN ESSENTIAL LIGHT CHAIN, ... | Authors: | Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, A.G, Cohen, C. | Deposit date: | 2001-12-06 | Release date: | 2002-10-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc.Natl.Acad.Sci.USA, 99, 2002
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1KQJ
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![BU of 1kqj by Molmil](/molmil-images/mine/1kqj) | Crystal Structure of a Mutant of MutY Catalytic Domain | Descriptor: | A/G-SPECIFIC ADENINE GLYCOSYLASE, GLYCEROL, IRON/SULFUR CLUSTER, ... | Authors: | Messick, T.E, Chmiel, N.H, Golinelli, M.P, David, S.S, Joshua-Tor, L. | Deposit date: | 2002-01-06 | Release date: | 2002-04-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster. Biochemistry, 41, 2002
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1KWO
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![BU of 1kwo by Molmil](/molmil-images/mine/1kwo) | SCALLOP MYOSIN S1-ATPgammaS-p-PDM IN THE ACTIN-DETACHED CONFORMATION | Descriptor: | 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | Deposit date: | 2002-01-30 | Release date: | 2002-11-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Crystallographic findings on the
internally uncoupled and near-rigor
states of myosin: Further insights into
the mechanics of the motor Proc.Natl.Acad.Sci.USA, 99, 2002
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1OD1
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![BU of 1od1 by Molmil](/molmil-images/mine/1od1) | Endothiapepsin PD135,040 complex | Descriptor: | ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide, SULFATE ION | Authors: | Coates, L, Erskine, P.T, Mall, S, Gill, R.S, Wood, S.P, Cooper, J.B. | Deposit date: | 2003-02-12 | Release date: | 2003-06-12 | Last modified: | 2012-11-30 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | The Structure of Endothiapepsin Complexed with the Gem-Diol Inhibitor Pd-135,040 at 1.37 A Acta Crystallogr.,Sect.D, 59, 2003
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1KIK
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![BU of 1kik by Molmil](/molmil-images/mine/1kik) | SH3 Domain of Lymphocyte Specific Kinase (LCK) | Descriptor: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK | Authors: | Briese, L, Willbold, D. | Deposit date: | 2001-12-03 | Release date: | 2001-12-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure determination of human Lck unique and SH3 domains by nuclear magnetic resonance spectroscopy. Bmc Struct.Biol., 3, 2003
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1NZF
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![BU of 1nzf by Molmil](/molmil-images/mine/1nzf) | T4 phage BGT-D100A mutant in complex with UDP-glucose: Form II | Descriptor: | CHLORIDE ION, DNA beta-glycosyltransferase, GLYCEROL, ... | Authors: | Lariviere, L, Morera, S. | Deposit date: | 2003-02-17 | Release date: | 2003-09-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with
UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism. J.Mol.Biol., 330, 2003
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1KJ0
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![BU of 1kj0 by Molmil](/molmil-images/mine/1kj0) | SOLUTION STRUCTURE OF THE SMALL SERINE PROTEASE INHIBITOR SGTI | Descriptor: | SERINE PROTEASE INHIBITOR I | Authors: | Gaspari, Z, Patthy, A, Graf, L, Perczel, A. | Deposit date: | 2001-12-04 | Release date: | 2001-12-12 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Comparative structure analysis of proteinase inhibitors from the desert locust, Schistocerca gregaria. Eur.J.Biochem., 269, 2002
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5U2G
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![BU of 5u2g by Molmil](/molmil-images/mine/5u2g) | 2.6 Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Minasov, G, Wawrzak, Z, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-11-30 | Release date: | 2016-12-28 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | 2.6 Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae. To Be Published
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1KU8
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![BU of 1ku8 by Molmil](/molmil-images/mine/1ku8) | Crystal structure of Jacalin | Descriptor: | JACALIN ALPHA CHAIN, JACALIN BETA CHAIN | Authors: | Bourne, Y, Astoul, C.H, Zamboni, V, Peumans, W.J, Menu-Bouaouiche, L, Van Damme, E.J.M, Barre, A, Rouge, P. | Deposit date: | 2002-01-21 | Release date: | 2002-06-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for the unusual carbohydrate-binding specificity of jacalin towards galactose and mannose. Biochem.J., 364, 2002
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1KJY
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![BU of 1kjy by Molmil](/molmil-images/mine/1kjy) | Crystal Structure of Human G[alpha]i1 Bound to the GoLoco Motif of RGS14 | Descriptor: | CESIUM ION, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT, ... | Authors: | Kimple, R.J, Kimple, M.E, Betts, L, Sondek, J, Siderovski, D.P. | Deposit date: | 2001-12-05 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits. Nature, 416, 2002
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1KKC
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![BU of 1kkc by Molmil](/molmil-images/mine/1kkc) | Crystal structure of Aspergillus fumigatus MnSOD | Descriptor: | MANGANESE (II) ION, Manganese Superoxide Dismutase | Authors: | Fluckiger, S, Mittl, P.R.E, Scapozza, L, Fijten, H, Folkers, G, Grutter, M.G, Blaser, K, Crameri, R. | Deposit date: | 2001-12-07 | Release date: | 2001-12-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution. J.Immunol., 168, 2002
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5TY5
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![BU of 5ty5 by Molmil](/molmil-images/mine/5ty5) | Neutron structure from microgravity-grown crystals of Inorganic Pyrophosphatase from Thermococcus theoreducens | Descriptor: | Inorganic pyrophosphatase | Authors: | Inoguchi, N, Coates, L, Morris, M.L, Singhal, A, Monaco, D.A, Garcia-Ruiz, J.M, Pusey, M.L, Ng, J.D. | Deposit date: | 2016-11-18 | Release date: | 2017-11-22 | Last modified: | 2023-10-04 | Method: | NEUTRON DIFFRACTION (2.3 Å) | Cite: | Structure-function analysis of the neutron crystallographic structure of inorganic pyrophosphatase determined from microgravity-grown crystals Acta Crystallogr.,Sect.A, 73, 2017
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1O7E
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![BU of 1o7e by Molmil](/molmil-images/mine/1o7e) | |
7AJK
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![BU of 7ajk by Molmil](/molmil-images/mine/7ajk) | Crystal structure of CRYI-B Rac1 complex | Descriptor: | CYFIP-related Rac1 interactor B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Yelland, T, Anh, L, Insall, R, Machesky, L, Ismail, S. | Deposit date: | 2020-09-29 | Release date: | 2020-11-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1. Structure, 29, 2021
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5TR3
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![BU of 5tr3 by Molmil](/molmil-images/mine/5tr3) | 2.5 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD. | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Minasov, G, Wawrzak, Z, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-10-25 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | 2.5 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD. To Be Published
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5U1O
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![BU of 5u1o by Molmil](/molmil-images/mine/5u1o) | 2.3 Angstrom Resolution Crystal Structure of Glutathione Reductase from Vibrio parahaemolyticus in Complex with FAD. | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Glutathione reductase, ... | Authors: | Minasov, G, Shuvalova, L, Cardona-Correa, A, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-11-28 | Release date: | 2016-12-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | 2.3 Angstrom Resolution Crystal Structure of Glutathione Reductase from Vibrio parahaemolyticus in Complex with FAD. To Be Published
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5TSE
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![BU of 5tse by Molmil](/molmil-images/mine/5tse) | 2.35 Angstrom Crystal Structure Minor Lipoprotein from Acinetobacter baumannii. | Descriptor: | FORMIC ACID, LPS-assembly lipoprotein LptE | Authors: | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-10-28 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | 2.35 Angstrom Crystal Structure Minor Lipoprotein from Acinetobacter baumannii. To Be Published
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1LU1
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![BU of 1lu1 by Molmil](/molmil-images/mine/1lu1) | THE STRUCTURE OF THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE FORSSMAN DISACCHARIDE | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ADENINE, CALCIUM ION, ... | Authors: | Hamelryck, T.W, Loris, R, Bouckaert, J, Strecker, G, Imberty, A, Fernandez, E, Wyns, L, Etzler, M.E. | Deposit date: | 1998-07-24 | Release date: | 1998-12-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus. J.Mol.Biol., 286, 1999
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1NOT
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![BU of 1not by Molmil](/molmil-images/mine/1not) | THE 1.2 ANGSTROM STRUCTURE OF G1 ALPHA CONOTOXIN | Descriptor: | GI ALPHA CONOTOXIN | Authors: | Guddat, L.W, Shan, L, Martin, J.L, Edmundson, A.B, Gray, W.R. | Deposit date: | 1996-05-02 | Release date: | 1996-12-07 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Three-dimensional structure of the alpha-conotoxin GI at 1.2 A resolution Biochemistry, 35, 1996
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