1RBZ
 
 | | Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid | | Descriptor: | N-{4-4-(2,4-DIAMINO-6-OXO-1,6-DIHYDRO-PYRIMIDIN-5-YL)-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXY-ETHYL)-BUT-2-YL-BENZOYL}-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GLUTAMIC ACID, PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | | Authors: | Zhang, Y, Desharnais, J, Boger, D.L, Wilson, I.A. | | Deposit date: | 2003-11-03 | | Release date: | 2005-06-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Human GAR Tfase complex structure
To be Published
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1RD8
 | | Crystal Structure of the 1918 Human H1 Hemagglutinin Precursor (HA0) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Stevens, J, Corper, A.L, Basler, C.F, Taubenberger, J.K, Palese, P, Wilson, I.A. | | Deposit date: | 2003-11-05 | | Release date: | 2004-03-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the Uncleaved Human H1 Hemagglutinin from the Extinct 1918 Influenza Virus.
Science, 303, 2004
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5U7G
 | | Crystal Structure of the Catalytic Core of CBP | | Descriptor: | CREB-binding protein, ZINC ION | | Authors: | Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E. | | Deposit date: | 2016-12-12 | | Release date: | 2017-06-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.401 Å) | | Cite: | Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UEI
 | | Crystal Structure of Variable Lymphocyte Receptor (VLR) O13 (Apo) | | Descriptor: | CHLORIDE ION, GLYCEROL, O13 | | Authors: | Gunn, R.J, Collins, B.C, McKitrick, T.R, Cummings, R.D, Herrin, B.R, Cooper, M.D, Wilson, I.A. | | Deposit date: | 2017-01-02 | | Release date: | 2017-10-18 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (1.702 Å) | | Cite: | Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.
Structure, 25, 2017
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5T3S
 | | HIV gp140 trimer MD39-10MUTA in complex with Fabs PGT124 and 35022 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2016-08-26 | | Release date: | 2016-09-28 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Immunity, 45, 2016
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5V2A
 | | Crystal structure of Fab H7.167 in complex with influenza virus hemagglutinin from A/Shanghai/02/2013 (H7N9) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H7.167 antibody, Hemagglutinin, ... | | Authors: | Zhang, H, Zhu, X, Wilson, I.A. | | Deposit date: | 2017-03-03 | | Release date: | 2017-04-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (4.656 Å) | | Cite: | H7N9 influenza virus neutralizing antibodies that possess few somatic mutations.
J. Clin. Invest., 126, 2016
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5T6N
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5T80
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5TGU
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5T6S
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5T85
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5UI4
 | | Structure of NME1 covalently conjugated to imidazole fluorosulfate | | Descriptor: | 4-[4-(3-methoxyphenyl)-1-(prop-2-yn-1-yl)-1H-imidazol-5-yl]phenyl sulfurofluoridate, Nucleoside diphosphate kinase A | | Authors: | Mortenson, D.E, Brighty, G.J, Wilson, I.A, Kelly, J.W. | | Deposit date: | 2017-01-12 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | "Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.
J. Am. Chem. Soc., 140, 2018
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1SQ2
 | | Crystal Structure Analysis of the Nurse Shark New Antigen Receptor (NAR) Variable Domain in Complex With Lysozyme | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | | Authors: | Stanfield, R.L, Dooley, H, Flajnik, M.F, Wilson, I.A. | | Deposit date: | 2004-03-17 | | Release date: | 2004-08-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Crystal structure of a shark single-domain antibody V region in complex with lysozyme.
Science, 305, 2004
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5TGV
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5UM8
 | | Crystal structure of HIV-1 envelope trimer 16055 NFL TD CC (T569G) in complex with Fabs 35022 and PGT124 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 35022 heavy chain, ... | | Authors: | Garces, F, Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2017-01-26 | | Release date: | 2017-05-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.935 Å) | | Cite: | Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein.
Immunity, 46, 2017
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5VJK
 | | Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | | Authors: | Zhu, X, Wilson, I.A. | | Deposit date: | 2017-04-19 | | Release date: | 2017-05-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.593 Å) | | Cite: | Three mutations switch H7N9 influenza to human-type receptor specificity.
PLoS Pathog., 13, 2017
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5UXQ
 | | Structure of anti-HIV trimer apex antibody PGT143 | | Descriptor: | PGT143 Fab Heavy Chain, PGT143 Fab Light Chain | | Authors: | Kong, L, Wilson, I.A. | | Deposit date: | 2017-02-23 | | Release date: | 2017-04-19 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.415 Å) | | Cite: | A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic Beta-Hairpin Structure
Immunity, 46, 2017
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5UY3
 | | Crystal structure of human Fab PGT144, a broadly reactive and potent HIV-1 neutralizing antibody | | Descriptor: | Antibody PGT144 Fab heavy chain, Antibody PGT144 Fab light chain | | Authors: | Julien, J.-P, Lee, J.H, Wilson, I.A. | | Deposit date: | 2017-02-23 | | Release date: | 2017-04-19 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure.
Immunity, 46, 2017
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5V7R
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5UMN
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5VTR
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5VU4
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5VJM
 | | Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9) with LSTa | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | | Authors: | Zhu, X, Wilson, I.A. | | Deposit date: | 2017-04-19 | | Release date: | 2017-05-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.909 Å) | | Cite: | Three mutations switch H7N9 influenza to human-type receptor specificity.
PLoS Pathog., 13, 2017
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5W42
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1T6V
 | | Crystal structure analysis of the nurse shark new antigen receptor (NAR) variable domain in complex with lysozyme | | Descriptor: | CHLORIDE ION, Lysozyme C, novel antigen receptor | | Authors: | Stanfield, R.L, Dooley, H, Flajnik, M.F, Wilson, I.A. | | Deposit date: | 2004-05-07 | | Release date: | 2004-08-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of a shark single-domain antibody V region in complex with lysozyme.
Science, 305, 2004
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