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3SZ1
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BU of 3sz1 by Molmil
Human PPAR gamma ligand binding domain in complex with luteolin and myristic acid
Descriptor: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, MYRISTIC ACID, Peroxisome proliferator-activated receptor gamma, ...
Authors:Puhl, A.C, Bernardes, A, Polikarpov, I.
Deposit date:2011-07-18
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mode of peroxisome proliferator-activated receptor gamma activation by luteolin.
Mol.Pharmacol., 81, 2012
2NQ3
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BU of 2nq3 by Molmil
Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
Descriptor: CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2006-10-30
Release date:2006-11-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
To be Published
8VTE
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BU of 8vte by Molmil
Co-structure of the Fab of the anti-TIGIT Vibostolimab antibody with its antigen
Descriptor: T-cell immunoreceptor with Ig and ITIM domains, Tiragolumab antibody heavy chain variable domains, Tiragolumab antibody light chain variable domains
Authors:Fischmann, T, Bahmanjah, S.
Deposit date:2024-01-26
Release date:2025-05-28
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Pharmacological and structural characterization of vibostolimab, a novel anti-human TIGIT blocking antibody for cancer immunotherapy
To Be Published
8VTD
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BU of 8vtd by Molmil
Co-structure of the Fab of the anti-TIGIT Vibostolimab antibody with its antigen
Descriptor: GLYCEROL, T-cell immunoreceptor with Ig and ITIM domains, Vibostolimab Fab Heavy chain, ...
Authors:Fischmann, T.
Deposit date:2024-01-26
Release date:2025-07-02
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Pharmacological and structural characterization of vibostolimab, a novel anti-human TIGIT blocking antibody for cancer immunotherapy
To Be Published
7BWJ
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BU of 7bwj by Molmil
crystal structure of SARS-CoV-2 antibody with RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ...
Authors:Wang, X, Ge, J.
Deposit date:2020-04-14
Release date:2020-06-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Human neutralizing antibodies elicited by SARS-CoV-2 infection.
Nature, 584, 2020
8IXN
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BU of 8ixn by Molmil
Curved structure of mPIEZO1-S2472E
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ...
Authors:Liu, S, Yang, X, Chen, X, Li, X, Xiao, B.
Deposit date:2023-04-01
Release date:2025-01-01
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:An intermediate open structure reveals the gating transition of the mechanically activated PIEZO1 channel.
Neuron, 113, 2025
8IXO
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BU of 8ixo by Molmil
Intermediate structure of mPIEZO1-S2472E
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ...
Authors:Liu, S, Yang, X, Chen, X, Li, X, Xiao, B.
Deposit date:2023-04-01
Release date:2025-01-01
Last modified:2025-03-05
Method:ELECTRON MICROSCOPY (4 Å)
Cite:An intermediate open structure reveals the gating transition of the mechanically activated PIEZO1 channel.
Neuron, 113, 2025
7WUA
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BU of 7wua by Molmil
Crystal structures of FadD32 from Corynebacterium diphtheriae
Descriptor: Acyl-CoA synthase, MAGNESIUM ION, MYRISTIC ACID, ...
Authors:Liu, X.
Deposit date:2022-02-07
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Crystal structures of FadD32 and pks13-ACP domain from Corynebacterium diphtheriae
Biochem Biophys Res Commun, 590, 2022
7WRP
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BU of 7wrp by Molmil
Crystal Structure of pks13-ACP domain from Corynebacterium diphtheriae
Descriptor: 4'-PHOSPHOPANTETHEINE, Polyketide synthase involved in mycolic acid biosynthesis
Authors:Liu, X.
Deposit date:2022-01-27
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:Crystal structures of FadD32 and pks13-ACP domain from Corynebacterium diphtheriae.
Biochem.Biophys.Res.Commun., 590, 2022
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