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7NIQ
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BU of 7niq by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(Major class)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-13
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
1RHZ
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BU of 1rhz by Molmil
The structure of a protein conducting channel
Descriptor: Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta
Authors:van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A.
Deposit date:2003-11-15
Release date:2004-01-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of a protein-conducting channel.
Nature, 427, 2004
4H22
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BU of 4h22 by Molmil
Crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1
Descriptor: Leucine-rich repeat flightless-interacting protein 1
Authors:Nguyen, J.B, Modis, Y.
Deposit date:2012-09-11
Release date:2012-11-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1.
J.Struct.Biol., 181, 2013
4HJC
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BU of 4hjc by Molmil
Crystal structure of glycoprotein C from Rift Valley Fever Virus (non-glycosylated)
Descriptor: ENVELOPE GLYCOPROTEIN
Authors:Dessau, M, Modis, Y.
Deposit date:2012-10-12
Release date:2013-01-16
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (4.15 Å)
Cite:Crystal structure of glycoprotein C from Rift Valley fever virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HJ1
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BU of 4hj1 by Molmil
Crystal structure of glycoprotein C from Rift Valley Fever Virus (glycosylated)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN, ...
Authors:Dessau, M, Modis, Y.
Deposit date:2012-10-12
Release date:2013-01-16
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of glycoprotein C from Rift Valley fever virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
6GJZ
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BU of 6gjz by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with AMPPNP
Descriptor: Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-05-17
Release date:2018-11-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GKH
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BU of 6gkh by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with ADP-AlF4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-05-21
Release date:2018-11-21
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6H61
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BU of 6h61 by Molmil
CryoEM structure of the MDA5-dsRNA filament with 89 degree twist and without nucleotide
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-07-25
Release date:2018-11-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GKM
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BU of 6gkm by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with ATP (10 mM)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-05-21
Release date:2018-11-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6H66
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BU of 6h66 by Molmil
CryoEM structure of the MDA5-dsRNA filament with 93 degree twist and without nucleotide
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-07-26
Release date:2018-11-21
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
4DQ7
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BU of 4dq7 by Molmil
Structural Investigation of Bacteriophage Phi6 Lysin (V207F mutant)
Descriptor: Membrane protein Phi6 P5
Authors:Dessau, M.A, Modis, Y.
Deposit date:2012-02-15
Release date:2013-01-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme.
PLoS Genet, 8, 2012
4DQJ
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BU of 4dqj by Molmil
Structural Investigation of Bacteriophage Phi6 Lysin (in complex with chitotetraose)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Membrane protein Phi6 P5
Authors:Dessau, M.A, Modis, Y.
Deposit date:2012-02-16
Release date:2013-01-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme.
PLoS Genet, 8, 2012
4DQ5
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BU of 4dq5 by Molmil
Structural Investigation of Bacteriophage Phi6 Lysin (WT)
Descriptor: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Membrane protein Phi6 P5wt
Authors:Dessau, M.A, Modis, Y.
Deposit date:2012-02-15
Release date:2013-01-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.395 Å)
Cite:Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme.
PLoS Genet, 8, 2012
4FH8
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BU of 4fh8 by Molmil
Crystal Structure of Peroxiredoxin-1 from the human hookworm Ancylostoma ceylanicum
Descriptor: AcePrx-1
Authors:Nguyen, J.B, Modis, Y.
Deposit date:2012-06-05
Release date:2013-06-12
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A.
Chem.Biol., 20, 2013
5J9H
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BU of 5j9h by Molmil
Crystal structure of Glycoprotein C from Puumala virus in the post-fusion conformation (pH 8.0)
Descriptor: Envelopment polyprotein, SULFATE ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Willensky, S, Dessau, M.
Deposit date:2016-04-10
Release date:2016-10-05
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation.
Plos Pathog., 12, 2016
5J81
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BU of 5j81 by Molmil
Crystal structure of Glycoprotein C from Puumala virus in the post-fusion conformation (pH 6.0)
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ACETATE ION, Envelopment polyprotein, ...
Authors:Willensky, S, Dessau, M.
Deposit date:2016-04-07
Release date:2016-10-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation.
Plos Pathog., 12, 2016
1AFW
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BU of 1afw by Molmil
THE 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE DIMERIC PEROXISOMAL THIOLASE OF SACCHAROMYCES CEREVISIAE
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 3-KETOACETYL-COA THIOLASE
Authors:Mathieu, M, Wierenga, R.K.
Deposit date:1997-03-15
Release date:1997-06-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism.
J.Mol.Biol., 273, 1997
4DT5
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BU of 4dt5 by Molmil
Crystal Structure of Rhagium inquisitor Antifreeze Protein
Descriptor: Antifreeze protein, GLYCEROL, SULFATE ION
Authors:Meng, W, Nguyen, J.B, Hakim, A, Thakral, D, Zhu, D.F.
Deposit date:2012-02-20
Release date:2013-03-13
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal structure of an insect antifreeze protein and its implications for ice binding.
J.Biol.Chem., 288, 2013
1HNU
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BU of 1hnu by Molmil
CRYSTAL STRUCTURE OF PEROXISOMAL DELTA3-DELTA2-ENOYL-COA ISOMERASE FROM SACCHAROMYCES CEREVISIAE
Descriptor: 1,2-ETHANEDIOL, D3,D2-ENOYL COA ISOMERASE ECI1, PERRHENATE
Authors:Mursula, A.M, van Aalten, D.M.F, Hiltunen, J.K, Wierenga, R.K.
Deposit date:2000-12-08
Release date:2001-06-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The crystal structure of delta(3)-delta(2)-enoyl-CoA isomerase.
J.Mol.Biol., 309, 2001
1K39
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BU of 1k39 by Molmil
The structure of yeast delta3-delta2-enoyl-COA isomerase complexed with octanoyl-COA
Descriptor: OCTANOYL-COENZYME A, PHOSPHATE ION, d3,d2-enoyl CoA isomerase ECI1
Authors:Mursula, A.M, Geerlof, A, Hiltunen, J.K, Wierenga, R.K.
Deposit date:2001-10-02
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:

1HNO
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BU of 1hno by Molmil
CRYSTAL STRUCTURE OF PEROXISOMAL DELTA3-DELTA2-ENOYL-COA ISOMERASE FROM SACCHAROMYCES CEREVISIAE
Descriptor: 1,2-ETHANEDIOL, D3,D2-ENOYL COA ISOMERASE ECI1
Authors:Mursula, A.M, van Aalten, D.M.F, Hiltunen, J.K, Wierenga, R.K.
Deposit date:2000-12-08
Release date:2001-06-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of delta(3)-delta(2)-enoyl-CoA isomerase.
J.Mol.Biol., 309, 2001
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