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7NRE
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BU of 7nre by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with darobactin (crystal form 1)
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Darobactin, MAGNESIUM ION, ...
Authors:Jakob, R.P, Kaur, H, Marzinek, J.K, Green, R, Imai, Y, Bolla, J, Robinson, C, Bond, P.J, Lewis, K, Maier, T, Hiller, S.
Deposit date:2021-03-03
Release date:2021-04-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase.
Nature, 593, 2021
7NRI
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BU of 7nri by Molmil
Structure of the darobactin-bound E. coli BAM complex (BamABCDE)
Descriptor: 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ...
Authors:Jakob, R.P, Kaur, H, Marzinek, J.K, Green, R, Imai, Y, Bolla, J, Robinson, C, Bond, P.J, Lewis, K, Maier, T, Hiller, S.
Deposit date:2021-03-03
Release date:2021-04-21
Last modified:2025-04-09
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase.
Nature, 593, 2021
7NGQ
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BU of 7ngq by Molmil
Human mitochondrial Lon protease homolog, D2-state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Mohammed, I, Abrahams, J.P, Schmitz, K.A, Maier, T, Schenck, N.
Deposit date:2021-02-09
Release date:2021-04-28
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGP
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BU of 7ngp by Molmil
D1-state of wild type human mitochondrial LONP1 protease
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-09
Release date:2021-04-28
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGF
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BU of 7ngf by Molmil
P2c-state of wild type human mitochondrial LONP1 protease with bound endogenous substrate protein and in presence of ATP/ADP mix
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-09
Release date:2021-04-28
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGL
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BU of 7ngl by Molmil
R-state of wild type human mitochondrial LONP1 protease bound to endogenous ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-09
Release date:2021-04-28
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7AYN
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BU of 7ayn by Molmil
Crystal structure of the lectin domain of the FimH variant Arg98Ala, in complex with Methyl 3-chloro-4-D-mannopyranosyloxy-3-biphenylcarboxylate
Descriptor: 1,2-ETHANEDIOL, Type 1 fimbrin D-mannose specific adhesin, methyl 3-[3-chloranyl-4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-phenyl]benzoate
Authors:Jakob, R.P, Tomasic, T, Rabbani, S, Reisner, A, Jakopin, Z, Maier, T, Ernst, B, Anderluh, M.
Deposit date:2020-11-12
Release date:2020-12-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Does targeting Arg98 of FimH lead to high affinity antagonists?
Eur.J.Med.Chem., 211, 2020
6QGY
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BU of 6qgy by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with nanobody B12
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, NanoB12, Outer membrane protein assembly factor BamA
Authors:Hartmann, J.-B, Kaur, H, Jakob, R.P, Zahn, M, Zimmermann, I, Seeger, M, Maier, T, Hiller, S.
Deposit date:2019-01-14
Release date:2019-06-26
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach.
J.Biomol.Nmr, 73, 2019
1W26
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BU of 1w26 by Molmil
Trigger Factor in Complex with the Ribosome forms a Molecular Cradle for Nascent Proteins
Descriptor: TRIGGER FACTOR
Authors:Ferbitz, L, Maier, T, Patzelt, H, Bukau, B, Deuerling, E, Ban, N.
Deposit date:2004-06-28
Release date:2004-09-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Trigger Factor in Complex with the Ribosome Forms a Molecular Cradle for Nascent Proteins
Nature, 431, 2004
1W2B
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BU of 1w2b by Molmil
Trigger Factor ribosome binding domain in complex with 50S
Descriptor: 23S RRNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L13P, ...
Authors:Ferbitz, L, Maier, T, Patzelt, H, Bukau, B, Deuerling, E, Ban, N.
Deposit date:2004-07-01
Release date:2004-09-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Trigger Factor in Complex with the Ribosome Forms a Molecular Cradle for Nascent Proteins
Nature, 431, 2004
8CG5
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BU of 8cg5 by Molmil
The ACP crosslinked to the KS of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS:ACP-MAT)
Descriptor: Acyl carrier protein (ACP) of Non-reducing polyketide synthase CTB1, Non-reducing polyketide synthase CTB1, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-[2-(propanoylamino)ethyl]-beta-alaninamide
Authors:Munoz-Hernandez, H, Tittes, Y.U, Maier, T.
Deposit date:2023-02-03
Release date:2024-02-21
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:CryoEM structure of ACP crosslinked to KS of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS:ACP-MAT) at 2.7 Angstroms resolution
To Be Published
8CG4
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BU of 8cg4 by Molmil
The organise full-length structure of the fungal non-reducing polyketide synthase (NR-PKS) PksA
Descriptor: Norsolorinic acid synthase
Authors:Munoz-Hernandez, H, Maier, T.
Deposit date:2023-02-03
Release date:2024-02-21
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:CryoEM structure of the Aspergilus sp. fungal non-reducing polyketide synthase (NR-PKS) PksA at 2.6 Angstroms resolution
To Be Published
8BP6
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BU of 8bp6 by Molmil
Structure of MHC-class I related molecule MR1 with bound M3Ade.
Descriptor: (1R,5S)-8-(9H-purin-6-yl)-2-oxa-8-azabicyclo[3.3.1]nona-3,6-diene-4,6-dicarbaldehyde, Beta-2-microglobulin,Major histocompatibility complex class I-related gene protein
Authors:Berloffa, G, Jakob, R.P, Maier, T.
Deposit date:2022-11-16
Release date:2023-11-29
Last modified:2025-02-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The carbonyl nucleobase adduct M 3 Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells.
Immunity, 2024
8BY8
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BU of 8by8 by Molmil
The cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS-MAT)
Descriptor: Non-reducing polyketide synthase CTB1
Authors:Munoz-Hernandez, H, Maier, T.
Deposit date:2022-12-12
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:The cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS-MAT) at 2.5 Angstroms resolution
To Be Published
8CG6
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BU of 8cg6 by Molmil
The ACP crosslinked to the SAT of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (ACP:SAT-KS-MAT)
Descriptor: Acyl carrier protein (ACP) of Non-reducing polyketide synthase CTB1, Non-reducing polyketide synthase CTB1, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-[2-(propanoylamino)ethyl]-beta-alaninamide
Authors:Munoz-Hernandez, H, Tittes, Y.U, Maier, T.
Deposit date:2023-02-03
Release date:2024-02-21
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:CryoEM structure of ACP crosslinked to SAT of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (ACP:SAT-KS-MAT) at 3.4 Angstroms resolution
To Be Published
7ZMC
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BU of 7zmc by Molmil
Ketosynthase domain of module 4 from Brevibacillus Brevis orphan BGC11
Descriptor: Putative polyketide synthase
Authors:Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T.
Deposit date:2022-04-19
Release date:2022-09-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structure of a polyketide synthase bimodule core.
Sci Adv, 8, 2022
7ZMA
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BU of 7zma by Molmil
Ketosynthase domain of module 4 from Brevibacillus Brevis orphan BGC11
Descriptor: Putative polyketide synthase
Authors:Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T.
Deposit date:2022-04-19
Release date:2022-09-21
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The structure of a polyketide synthase bimodule core.
Sci Adv, 8, 2022
7ZM9
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BU of 7zm9 by Molmil
Ketosynthase domain 3 of Brevibacillus Brevis orphan BGC11
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative polyketide synthase
Authors:Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T.
Deposit date:2022-04-19
Release date:2022-09-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:The structure of a polyketide synthase bimodule core.
Sci Adv, 8, 2022
7ZMF
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BU of 7zmf by Molmil
Dehydratase domain of module 3 from Brevibacillus Brevis orphan BGC11
Descriptor: GLYCEROL, MAGNESIUM ION, Putative polyketide synthase
Authors:Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T.
Deposit date:2022-04-19
Release date:2022-09-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The structure of a polyketide synthase bimodule core.
Sci Adv, 8, 2022
7ZMD
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BU of 7zmd by Molmil
Ketosynthase domain of module 3 from Brevibacillus Brevis orphan BGC11
Descriptor: Putative polyketide synthase
Authors:Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T.
Deposit date:2022-04-19
Release date:2022-09-21
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:The structure of a polyketide synthase bimodule core.
Sci Adv, 8, 2022
7ZSK
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BU of 7zsk by Molmil
K3DAK4 bimodule core of BGC11 from Brevibacillus brevis.
Descriptor: Putative polyketide synthase
Authors:Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T.
Deposit date:2022-05-07
Release date:2022-09-21
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:The structure of a polyketide synthase bimodule core.
Sci Adv, 8, 2022
2Z9A
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BU of 2z9a by Molmil
Crystal Structure of Human Saposin C Dimer in Open Conformation
Descriptor: GLYCEROL, Proactivator polypeptide
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-09-18
Release date:2008-04-29
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2VRH
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BU of 2vrh by Molmil
Structure of the E. coli trigger factor bound to a translating ribosome
Descriptor: 50S RIBOSOMAL PROTEIN L23, 50S RIBOSOMAL PROTEIN L24, 50S RIBOSOMAL PROTEIN L29, ...
Authors:Merz, F, Boehringer, D, Schaffitzel, C, Preissler, S, Hoffmann, A, Maier, T, Rutkowska, A, Lozza, J, Ban, N, Bukau, B, Deuerling, E.
Deposit date:2008-04-07
Release date:2008-06-17
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (19 Å)
Cite:Molecular Mechanism and Structure of Trigger Factor Bound to the Translating Ribosome.
Embo J., 27, 2008
2WCD
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BU of 2wcd by Molmil
Crystal structure of the assembled cytolysin A pore
Descriptor: ETHYL MERCURY ION, HEMOLYSIN E, CHROMOSOMAL
Authors:Mueller, M, Grauschopf, U, Maier, T, Glockshuber, R, Ban, N.
Deposit date:2009-03-11
Release date:2009-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:The Structure of a Cytolytic Alpha-Helical Toxin Pore Reveals its Assembly Mechanism
Nature, 459, 2009
5EX1
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BU of 5ex1 by Molmil
Crystal structure of cyclophilin AquaCyp300 from Hirschia baltica
Descriptor: MAGNESIUM ION, Peptidyl-prolyl cis-trans isomerase cyclophilin type
Authors:Jakob, R.P, Maier, T.
Deposit date:2015-11-23
Release date:2016-06-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:Structural and Functional Characterization of a Novel Family of Cyclophilins, the AquaCyps.
Plos One, 11, 2016

238582

数据于2025-07-09公开中

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