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6OUU
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BU of 6ouu by Molmil
Symmetric reconstruction of human norovirus GII.4 Minerva strain VLP in T=4 symmetry
Descriptor: Major capsid protein
Authors:Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
Deposit date:2019-05-05
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
5W0N
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BU of 5w0n by Molmil
Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, IODIDE ION, MAGNESIUM ION, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
5W0O
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BU of 5w0o by Molmil
Structure of human TUT7 catalytic module (CM) in complex with dsRNA
Descriptor: Terminal uridylyltransferase 7, URIDINE 5'-TRIPHOSPHATE, double-stranded RNA
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.488 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
1KQJ
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BU of 1kqj by Molmil
Crystal Structure of a Mutant of MutY Catalytic Domain
Descriptor: A/G-SPECIFIC ADENINE GLYCOSYLASE, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Messick, T.E, Chmiel, N.H, Golinelli, M.P, David, S.S, Joshua-Tor, L.
Deposit date:2002-01-06
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.
Biochemistry, 41, 2002
5W0B
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BU of 5w0b by Molmil
Structure of human TUT7 catalytic module (CM)
Descriptor: IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-30
Release date:2017-06-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.614 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
1KOU
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BU of 1kou by Molmil
Crystal Structure of the Photoactive Yellow Protein Reconstituted with Caffeic Acid at 1.16 A Resolution
Descriptor: CAFFEIC ACID, N-BUTANE, PHOTOACTIVE YELLOW PROTEIN
Authors:van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:2001-12-22
Release date:2002-04-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 A resolution.
Acta Crystallogr.,Sect.D, 58, 2002
1Z26
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BU of 1z26 by Molmil
Structure of Pyrococcus furiosus Argonaute with bound tungstate
Descriptor: Argonaute, TUNGSTATE(VI)ION
Authors:Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L.
Deposit date:2005-03-07
Release date:2005-04-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
1Z25
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BU of 1z25 by Molmil
Structure of P.furiosus Argonaute with bound Mn2+
Descriptor: Argonaute, MANGANESE (II) ION
Authors:Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L.
Deposit date:2005-03-07
Release date:2005-04-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
1ZRO
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BU of 1zro by Molmil
Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose
Descriptor: CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II
Authors:Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L.
Deposit date:2005-05-19
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
1ZRL
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BU of 1zrl by Molmil
Crystal structure of EBA-175 Region II (RII)
Descriptor: CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II
Authors:Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L.
Deposit date:2005-05-19
Release date:2005-08-09
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
5UJM
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BU of 5ujm by Molmil
Structure of the active form of human Origin Recognition Complex and its ATPase motor module
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Tocilj, A, On, K, Yuan, Z, Sun, J, Elkayam, E, Li, H, Stillman, B, Joshua-Tor, L.
Deposit date:2017-01-18
Release date:2017-02-08
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
Elife, 6, 2017
5UJ8
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BU of 5uj8 by Molmil
Human Origin Recognition Complex subunits 2 and 3
Descriptor: Origin recognition complex subunit 2, Origin recognition complex subunit 3
Authors:Tocilj, A, On, K.F, Elkayam, E, Joshua-Tor, L.
Deposit date:2017-01-17
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6 Å)
Cite:Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
Elife, 6, 2017
5UJ7
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BU of 5uj7 by Molmil
Structure of the active form of human Origin Recognition Complex ATPase motor module, complex subunitS 1, 4, 5
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Tocilj, A, Elkayam, E, On, K.F, Joshua-Tor, L.
Deposit date:2017-01-17
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.394 Å)
Cite:Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
Elife, 6, 2017
5T7B
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BU of 5t7b by Molmil
Argonaute-2 - 5'-(E)-vinylphosphonate 2'-O-methyl-uridine modified mrTTR guide RNA complex
Descriptor: PHENOL, Protein argonaute-2, RNA (UVP)UAUAGAGCAAGAACACUGUU
Authors:Elkayam, E, Joshua-Tor, L.
Deposit date:2016-09-02
Release date:2016-12-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.529 Å)
Cite:Protein structure
To Be Published
5VF6
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BU of 5vf6 by Molmil
Crystal structure of single chain variable fragment (scFv45).
Descriptor: single chain variable fragment
Authors:Shrestha, O.K, Tocilj, A, Joshua-Tor, L, Tonks, N.K.
Deposit date:2017-04-06
Release date:2018-01-31
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.635 Å)
Cite:Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development.
Nat Commun, 9, 2018
5W0M
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BU of 5w0m by Molmil
Structure of human TUT7 catalytic module (CM) in complex with U5 RNA
Descriptor: IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
2E00
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BU of 2e00 by Molmil
Crystal structure of N392L mutant of yeast bleomycin hydrolase
Descriptor: Cysteine proteinase 1
Authors:O'Farrell, P.A, Joshua-Tor, L.
Deposit date:2006-10-01
Release date:2007-11-06
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure
Biochem.J., 401, 2007
2E02
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BU of 2e02 by Molmil
Crystal structure of H369L mutant of yeast bleomycin hydrolase
Descriptor: Cysteine proteinase 1
Authors:O'Farrell, P.A, Joshua-Tor, L.
Deposit date:2006-10-01
Release date:2007-08-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure
Biochem.J., 401, 2007
2DZZ
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BU of 2dzz by Molmil
Crystal structure of N392V mutant of yeast bleomycin hydrolase
Descriptor: Cysteine proteinase 1
Authors:O'Farrell, P.A, Joshua-Tor, L.
Deposit date:2006-09-30
Release date:2007-08-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure
Biochem.J., 401, 2007
2E03
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BU of 2e03 by Molmil
Crystal structure of NQ67E mutant of yeast bleomycin hydrolase
Descriptor: Cysteine proteinase 1
Authors:O'Farrell, P.A, Joshua-Tor, L.
Deposit date:2006-10-01
Release date:2007-08-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure
Biochem.J., 401, 2007
2E01
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BU of 2e01 by Molmil
Crystal structure of H369A mutant of yeast bleomycin hydrolase
Descriptor: Cysteine proteinase 1
Authors:O'Farrell, P.A, Joshua-Tor, L.
Deposit date:2006-10-01
Release date:2007-08-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure
Biochem.J., 401, 2007
2DZY
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BU of 2dzy by Molmil
Crystal structure of N392A mutant of yeast bleomycin hydrolase
Descriptor: Cysteine proteinase 1
Authors:O'Farrell, P.A, Joshua-Tor, L.
Deposit date:2006-09-30
Release date:2007-08-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure
Biochem.J., 401, 2007
2CB5
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BU of 2cb5 by Molmil
HUMAN BLEOMYCIN HYDROLASE, C73S/DELE455 MUTANT
Descriptor: PROTEIN (BLEOMYCIN HYDROLASE)
Authors:O'Farrell, P.A, Gonzalez, F, Zheng, W, Johnston, S.A, Joshua-Tor, L.
Deposit date:1999-03-02
Release date:2000-03-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease.
Structure Fold.Des., 7, 1999
4X4N
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BU of 4x4n by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix
Descriptor: CCA-adding enzyme, G70A tRNA minihelix, GLYCEROL, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.953 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
4X4W
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BU of 4x4w by Molmil
Crystal structure of the full-length human mitochondrial CCA-adding enzyme
Descriptor: CCA tRNA nucleotidyltransferase 1, mitochondrial, CHLORIDE ION, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015

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