3R8W
| Structure of 3-isopropylmalate dehydrogenase isoform 2 from Arabidopsis thaliana at 2.2 angstrom resolution | Descriptor: | 3-isopropylmalate dehydrogenase 2, chloroplastic, ACETATE ION | Authors: | He, Y, Galant, A, Pang, Q, Strul, J.M, Balogun, S, Jez, J.M, Chen, S. | Deposit date: | 2011-03-24 | Release date: | 2011-06-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and functional evolution of isopropylmalate dehydrogenases in the leucine and glucosinolate pathways of Arabidopsis thaliana. J.Biol.Chem., 286, 2011
|
|
1ZXH
| G311 mutant protein | Descriptor: | Immunoglobulin G binding protein G | Authors: | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | Deposit date: | 2005-06-08 | Release date: | 2005-11-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds. Biochemistry, 44, 2005
|
|
1ZXG
| Solution structure of A219 | Descriptor: | Immunoglobulin G binding protein A | Authors: | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | Deposit date: | 2005-06-08 | Release date: | 2005-11-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds. Biochemistry, 44, 2005
|
|
4P6W
| Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain | Descriptor: | Glucocorticoid receptor, MOMETASONE FUROATE, Nuclear receptor coactivator 2 | Authors: | He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E. | Deposit date: | 2014-03-25 | Release date: | 2014-04-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.951 Å) | Cite: | Structures and mechanism for the design of highly potent glucocorticoids. Cell Res., 24, 2014
|
|
2XM1
| BtGH84 in complex with N-acetyl gluconolactam | Descriptor: | GLYCEROL, N-ACETYL GLUCONOLACTAM, O-GLCNACASE BT_4395 | Authors: | He, Y, Davies, G.J. | Deposit date: | 2010-07-22 | Release date: | 2011-08-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inhibition of a Bacterial O-Glcnacase Homologue by Lactone and Lactam Derivatives: Structural, Kinetic and Thermodynamic Analyses. Amino Acids, 40, 2011
|
|
4P6X
| Crystal Structure of cortisol-bound glucocorticoid receptor ligand binding domain | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Glucocorticoid receptor, Nuclear receptor coactivator 2 | Authors: | He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E. | Deposit date: | 2014-03-25 | Release date: | 2014-04-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures and mechanism for the design of highly potent glucocorticoids. Cell Res., 24, 2014
|
|
4OIC
| Crystal structrual of a soluble protein | Descriptor: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Bet v I allergen-like, CHLORIDE ION, ... | Authors: | He, Y, Hao, Q, Li, W, Yan, C, Yan, N, Yin, P. | Deposit date: | 2014-01-19 | Release date: | 2015-01-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Identification and characterization of ABA receptors in Oryza sativa Plos One, 9, 2014
|
|
6LCP
| Cryo-EM structure of Dnf1 from Chaetomium thermophilum in the E2P state | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | He, Y, Xu, J, Wu, X, Li, L. | Deposit date: | 2019-11-19 | Release date: | 2020-04-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structures of a P4-ATPase lipid flippase in lipid bilayers. Protein Cell, 11, 2020
|
|
6LCR
| Cryo-EM structure of Dnf1 from Chaetomium thermophilum in the E1-ATP state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cdc50, ... | Authors: | He, Y, Xu, J, Wu, X, Li, L. | Deposit date: | 2019-11-19 | Release date: | 2020-04-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of a P4-ATPase lipid flippase in lipid bilayers. Protein Cell, 11, 2020
|
|
7D3M
| |
7D3K
| |
7D3R
| |
7D3L
| |
7FEJ
| Complex of FMDV A/AF/72 and bovine neutralizing scFv antibody R55 | Descriptor: | A/AF/72 VP1, A/AF/72 VP2, A/AF/72 VP3, ... | Authors: | He, Y, Li, K, Lou, Z. | Deposit date: | 2021-07-20 | Release date: | 2021-09-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization. J.Virol., 95, 2021
|
|
7FEI
| Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody R55 | Descriptor: | Capsid protein VP0, IG HEAVY CHAIN VARIABLE REGION, IG LAMDA CHAIN VARIABLE REGION | Authors: | He, Y, Li, K, Lou, Z. | Deposit date: | 2021-07-20 | Release date: | 2021-09-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization. J.Virol., 95, 2021
|
|
7UY8
| Tetrahymena Polymerase alpha-Primase | Descriptor: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-05-06 | Release date: | 2022-07-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
|
|
7MN2
| Rules for designing protein fold switches and their implications for the folding code | Descriptor: | Sb2 | Authors: | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | Deposit date: | 2021-04-30 | Release date: | 2022-05-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
|
|
7MP7
| Rules for designing protein fold switches and their implications for the folding code | Descriptor: | Sb3 | Authors: | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | Deposit date: | 2021-05-04 | Release date: | 2022-05-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
|
|
7MN1
| Rules for designing protein fold switches and their implications for the folding code | Descriptor: | Sa1 | Authors: | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | Deposit date: | 2021-04-30 | Release date: | 2022-05-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
|
|
7MQ4
| Rules for designing protein fold switches and their implications for the folding code | Descriptor: | Sb1 | Authors: | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | Deposit date: | 2021-05-05 | Release date: | 2022-05-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
|
|
7YUB
| S1P-bound human SPNS2 | Descriptor: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, NbFab-H-chain, NbFab-L-chain, ... | Authors: | He, Y, Duan, Y. | Deposit date: | 2022-08-17 | Release date: | 2023-09-06 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Structural basis of Sphingosine-1-phosphate transport via human SPNS2. Cell Res., 34, 2024
|
|
7YDM
| Cryo-EM structure of CD97/Gq complex | Descriptor: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | He, Y, Wang, N. | Deposit date: | 2022-07-04 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structural basis of CD97 activation and G-protein coupling. Cell Chem Biol, 30, 2023
|
|
7YDP
| Cryo-EM structure of CD97/miniGs complex | Descriptor: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | He, Y, Wang, N. | Deposit date: | 2022-07-04 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of CD97 activation and G-protein coupling. Cell Chem Biol, 30, 2023
|
|
7YDH
| Cryo EM structure of CD97/miniG13 complex | Descriptor: | Adhesion G protein-coupled receptor E5 subunit beta, G protein subunit 13 (Gi2-mini-G13 chimera), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | He, Y, Wang, N. | Deposit date: | 2022-07-04 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of CD97 activation and G-protein coupling. Cell Chem Biol, 30, 2023
|
|
8JXT
| Histamine-bound H4R/Gi complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | He, Y, Xia, R. | Deposit date: | 2023-07-01 | Release date: | 2024-03-20 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural basis of ligand recognition and design of antihistamines targeting histamine H 4 receptor. Nat Commun, 15, 2024
|
|