5K25
 
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1ME0
 | | Chimeric hairpin with 2',5'-linked RNA loop and DNA stem | | Descriptor: | DNA/RNA (5'-D(*GP*GP*AP*C)-R(P*(U25)P*(U25)P*(C25)P*(5GP))-D(P*GP*TP*CP*C)-3') | | Authors: | Denisov, A.Y, Hannoush, R.N, Gehring, K, Damha, M.J. | | Deposit date: | 2002-08-07 | | Release date: | 2003-08-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A Novel RNA Motif Based on the Structure of Unusually Stable 2',5'-Linked r(UUCG) Loops
J.AM.CHEM.SOC., 125, 2003
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5K22
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2QHO
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7SOT
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7SOV
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7SOQ
 | | LaM domain of human LARP1 in complex with AAA RNA | | Descriptor: | Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*A)-3') | | Authors: | Kozlov, G, Gehring, K. | | Deposit date: | 2021-11-01 | | Release date: | 2022-08-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
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7SOO
 | | LaM domain of human LARP1 | | Descriptor: | Isoform 2 of La-related protein 1, SODIUM ION, SULFATE ION | | Authors: | Kozlov, G, Gehring, K. | | Deposit date: | 2021-11-01 | | Release date: | 2022-08-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
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7SOP
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7SOR
 | | LaM domain of human LARP1 in complex with AAA RNA | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Isoform 2 of La-related protein 1, ... | | Authors: | Kozlov, G, Gehring, K. | | Deposit date: | 2021-11-01 | | Release date: | 2022-08-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
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7SOU
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7SOS
 | | LaM domain of human LARP1 in complex with AAAA RNA | | Descriptor: | Isoform 2 of La-related protein 1, POTASSIUM ION, RNA (5'-R(*AP*AP*AP*A)-3') | | Authors: | Kozlov, G, Gehring, K. | | Deposit date: | 2021-11-01 | | Release date: | 2022-08-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
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7SOW
 | | LaM domain of human LARP1 in complex with UUUUUU | | Descriptor: | 1,2-ETHANEDIOL, Isoform 2 of La-related protein 1, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3') | | Authors: | Kozlov, G, Gehring, K. | | Deposit date: | 2021-11-01 | | Release date: | 2022-11-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structural basis of 3'-end RNA recognition by LARP1
To Be Published
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8W31
 | | Crystal structure of parkin (R0RB):2pUb with activator compound | | Descriptor: | (S)-1-(6-benzyl-3-(4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)phenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)ethan-1-one, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | | Authors: | Sauve, V, Gehring, K. | | Deposit date: | 2024-02-21 | | Release date: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Activation of Parkin by a Molecular Glue
Nat Commun, 2024
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2X5N
 | | Crystal Structure of the SpRpn10 VWA domain | | Descriptor: | 26S PROTEASOME REGULATORY SUBUNIT RPN10, SULFATE ION | | Authors: | Riedinger, C, Boehringer, J, Trempe, J.-F, Lowe, E.D, Brown, N.R, Gehring, K, Noble, M.E.M, Gordon, C, Endicott, J.A. | | Deposit date: | 2010-02-10 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The Structure of Rpn10 and its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12.
J.Biol.Chem., 285, 2010
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7US1
 | | Structure of parkin (R0RB) bound to two phospho-ubiquitin molecules | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin, ... | | Authors: | Fakih, R, Sauve, V, Gehring, K. | | Deposit date: | 2022-04-22 | | Release date: | 2022-06-22 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.484 Å) | | Cite: | Structure of the second phosphoubiquitin-binding site in parkin.
J.Biol.Chem., 298, 2022
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5BTW
 | | Structure of the N-terminal domain of lpg1496 from Legionella pneumophila | | Descriptor: | Uncharacterized protein | | Authors: | Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | Deposit date: | 2015-06-03 | | Release date: | 2015-08-26 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
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5BU2
 | | Structure of the C-terminal domain of lpg1496 from Legionella pneumophila in complex with nucleotide | | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, alpha-D-ribofuranose, ... | | Authors: | Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | Deposit date: | 2015-06-03 | | Release date: | 2015-08-26 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
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5TDA
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1D5G
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5BTX
 | | Structure of the N-terminal domain of lpg1496 from Legionella pneumophila in complex with nucleotide | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, lpg1496 | | Authors: | Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | Deposit date: | 2015-06-03 | | Release date: | 2015-08-26 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
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5BU0
 | | Structure of the C-terminal domain of lpg1496 from Legionella pneumophila | | Descriptor: | lpg1496 | | Authors: | Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | Deposit date: | 2015-06-03 | | Release date: | 2015-08-26 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
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5BTZ
 | | Structure of the middle domain of lpg1496 from Legionella pneumophila in P212121 space group | | Descriptor: | lpg1496 | | Authors: | Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | Deposit date: | 2015-06-03 | | Release date: | 2015-08-26 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
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5BU1
 | | Structure of the truncated C-terminal domain of lpg1496 from Legionella pneumophila | | Descriptor: | LPG1496, MALONATE ION | | Authors: | Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | Deposit date: | 2015-06-03 | | Release date: | 2015-08-26 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
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4EEW
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