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6DZE
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BU of 6dze by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox7
Descriptor: CPfox7
Authors:Sun, Y.-T, Varani, G.
Deposit date:2018-07-03
Release date:2019-05-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
6DZB
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BU of 6dzb by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox5
Descriptor: CPfox5
Authors:Sun, Y.-T, Varani, G.
Deposit date:2018-07-03
Release date:2019-05-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
2A9X
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BU of 2a9x by Molmil
TAR RNA recognition by a cyclic peptidomimetic of Tat protein
Descriptor: BIV TAR RNA, BIV-2 cyclic peptide
Authors:Leeper, T.C, Athanassiou, Z, Dias, R.L, Robinson, J.A, Varani, G.
Deposit date:2005-07-12
Release date:2005-11-01
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:TAR RNA recognition by a cyclic peptidomimetic of Tat protein.
Biochemistry, 44, 2005
2APO
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BU of 2apo by Molmil
Crystal Structure of the Methanococcus jannaschii Cbf5 Nop10 Complex
Descriptor: POTASSIUM ION, Probable tRNA pseudouridine synthase B, Ribosome biogenesis protein Nop10, ...
Authors:Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
Deposit date:2005-08-16
Release date:2005-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
1Z31
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BU of 1z31 by Molmil
The structure of an enzyme-activating fragment of human telomerase RNA
Descriptor: human telomerase PJ6 hairpin
Authors:Leeper, T.C, Varani, G.
Deposit date:2005-03-10
Release date:2005-03-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of an enzyme-activating fragment of human telomerase RNA.
RNA, 11, 2005
6BES
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BU of 6bes by Molmil
Solution structure of de novo macrocycle design11_ss
Descriptor: (DAL)Q(DPR)(DCY)(DLY)DS(DTY)(DCY)P(DSN)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BF3
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BU of 6bf3 by Molmil
Solution structure of de novo macrocycle design7.3a
Descriptor: QDP(DPR)K(2TL)(DAS)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2018-01-10
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BE7
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BU of 6be7 by Molmil
Solution structure of de novo macrocycle Design8.1
Descriptor: DDPT(DPR)(DAR)Q(DGN)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-24
Release date:2018-01-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEN
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BU of 6ben by Molmil
Solution structure of de novo macrocycle design8.2
Descriptor: (DAR)Q(DPR)(DGN)R(DGL)PQ
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, B.
Deposit date:2017-10-25
Release date:2017-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BET
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BU of 6bet by Molmil
Solution structure of de novo macrocycle design12_ss
Descriptor: H(DPR)(DVA)CIP(DPR)E(DLY)VC(DGL)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEW
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BU of 6bew by Molmil
Solution structure of de novo macrocycle design7.2
Descriptor: (DHI)P(DAS)(DGN)(DSN)(DGL)P
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BF5
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BU of 6bf5 by Molmil
Solution structure of de novo macrocycle design7.3a
Descriptor: QDP(DPR)K(DTH)(DAS)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2018-01-10
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BER
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BU of 6ber by Molmil
Solution structure of de novo macrocycle design10.2
Descriptor: E(DVA)DP(DGL)(DHI)(DPR)N(DAL)(DPR)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEO
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BU of 6beo by Molmil
Solution structure of de novo macrocycle design9.1
Descriptor: (DPR)PY(DHI)PKDL(DGN)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEQ
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BU of 6beq by Molmil
Solution structure of de novo macrocycle design10.1
Descriptor: AAR(DVA)(DPR)R(DLE)(DTH)PE
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2018-01-10
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEU
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BU of 6beu by Molmil
Solution structure of de novo macrocycle design14_ss
Descriptor: (DCY)N(DVA)(DPR)DVYC(DPR)(DSG)KY(DVA)(DPR)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BE9
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BU of 6be9 by Molmil
Solution structure of de novo macrocycle design7.1
Descriptor: T(DLY)NDT(DSG)(DPR)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, B.
Deposit date:2017-10-24
Release date:2017-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6B3X
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BU of 6b3x by Molmil
Crystal structure of CstF-50 in complex with CstF-77
Descriptor: Cleavage stimulation factor subunit 1, Cleavage stimulation factor subunit 3
Authors:Yang, W, Hsu, P, Yang, F, Song, J.E, Varani, G.
Deposit date:2017-09-25
Release date:2017-11-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3'-end processing signals.
Nucleic Acids Res., 46, 2018
6C2V
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BU of 6c2v by Molmil
Solution structure of a phosphate-loop protein
Descriptor: phosphate-loop protein
Authors:Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
Deposit date:2018-01-09
Release date:2018-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C2U
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BU of 6c2u by Molmil
Solution structure of a phosphate-loop protein
Descriptor: phosphate-loop protein
Authors:Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
Deposit date:2018-01-09
Release date:2018-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6D2U
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BU of 6d2u by Molmil
Solution structure of a ultra-high affinity macrocycle bound to HIV-1 TAR RNA
Descriptor: DAB-VAL-ARG-THR-ARG-LYS-GLY-ARG-ARG-ILE-NOR-ILE-DPR-PRO, RNA (29-MER)
Authors:Shortridge, M.D, Varani, G.
Deposit date:2018-04-13
Release date:2018-12-12
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb.
Nucleic Acids Res., 47, 2019
2LWK
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BU of 2lwk by Molmil
Solution structure of small molecule-influenza RNA complex
Descriptor: 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine, RNA (32-MER)
Authors:Lee, M.-K, Varani, G, Choi, B.-S, Pellecchia, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-08-01
Release date:2012-08-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication.
Chem.Commun.(Camb.), 50, 2014
2N6T
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BU of 2n6t by Molmil
NMR Assignment and NMR Structure of CssA3 (top stem) of CssA thermometer
Descriptor: RNA (42-MER)
Authors:Barnwal, R, Godin, K, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-08-28
Release date:2016-08-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure and mechanism of a molecular rheostat, an RNA thermometer that modulates immune evasion by Neisseria meningitidis.
Nucleic Acids Res., 44, 2016
2N6X
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BU of 2n6x by Molmil
NMR Assignment and structure of CssA5 (middle region) of CssA thermometer from Neisseria meningitidis
Descriptor: RNA (43-MER)
Authors:Barnwal, R, Godin, K, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-08-31
Release date:2016-08-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and mechanism of a molecular rheostat, an RNA thermometer that modulates immune evasion by Neisseria meningitidis.
Nucleic Acids Res., 44, 2016
2MRL
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BU of 2mrl by Molmil
Backbone 1H, 13C, and 15N Chemical Shift Assignments and NMR structure for potential drug target from Burkholderia thailandensis E264
Descriptor: Uncharacterized protein BTH I2711
Authors:Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-07-09
Release date:2014-07-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structure for potential drug target from Burkholderia thailandensis E264
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