4CKC
| Vaccinia virus capping enzyme complexed with SAH (monoclinic form) | Descriptor: | MRNA-CAPPING ENZYME CATALYTIC SUBUNIT, MRNA-CAPPING ENZYME REGULATORY SUBUNIT, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Kyrieleis, O.J.P, Chang, J, de la Pena, M, Shuman, S, Cusack, S. | Deposit date: | 2014-01-02 | Release date: | 2014-03-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of Vaccinia Virus Mrna Capping Enzyme Provides Insights Into the Mechanism and Evolution of the Capping Apparatus. Structure, 22, 2014
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4CKB
| Vaccinia virus capping enzyme complexed with GTP and SAH | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MRNA-CAPPING ENZYME CATALYTIC SUBUNIT, MRNA-CAPPING ENZYME REGULATORY SUBUNIT, ... | Authors: | Kyrieleis, O.J.P, Chang, J, de la Pena, M, Shuman, S, Cusack, S. | Deposit date: | 2014-01-02 | Release date: | 2014-03-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Vaccinia Virus Mrna Capping Enzyme Provides Insights Into the Mechanism and Evolution of the Capping Apparatus. Structure, 22, 2014
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4GP7
| Polynucleotide kinase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ... | Authors: | Wang, L.K, Das, U, Smith, P, Shuman, S. | Deposit date: | 2012-08-20 | Release date: | 2012-11-14 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. Rna, 18, 2012
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1YN9
| Crystal structure of baculovirus RNA 5'-phosphatase complexed with phosphate | Descriptor: | PHOSPHATE ION, polynucleotide 5'-phosphatase | Authors: | Changela, A, Martins, A, Shuman, S, Mondragon, A. | Deposit date: | 2005-01-24 | Release date: | 2005-02-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of baculovirus RNA triphosphatase complexed with phosphate J.Biol.Chem., 280, 2005
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5H8A
| Mmi1 YTH domain | Descriptor: | YTH domain-containing protein mmi1 | Authors: | Chatterjee, D, Goldgur, Y, Shuman, S. | Deposit date: | 2015-12-23 | Release date: | 2016-01-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast. Rna, 22, 2016
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4GP6
| Polynucleotide kinase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Metallophosphoesterase | Authors: | Wang, L.K, Das, U, Smith, P, Shuman, S. | Deposit date: | 2012-08-20 | Release date: | 2012-11-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. Rna, 18, 2012
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5HFZ
| Mmi1 YTH domain | Descriptor: | YTH domain-containing protein mmi1 | Authors: | Chatterjee, D, Goldgur, Y, Shuman, S. | Deposit date: | 2016-01-07 | Release date: | 2016-02-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast. Rna, 22, 2016
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8TG3
| tRNA 2'-phosphotransferase (Tpt1) from Aeropyrum pernix in complex with ADP-ribose-1" -phosphate | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NITRATE ION, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2023-07-12 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120, 2023
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8TFY
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8TG4
| tRNA 2'-phosphotransferase (Tpt1) from Aeropyrum pernix in complex with ADP-ribose-2"-phosphate and 2'-OH RNA | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, NITRATE ION, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2023-07-12 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120, 2023
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8TFI
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8TFZ
| tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with NAD | Descriptor: | CHLORIDE ION, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2023-07-12 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120, 2023
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8TFX
| tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with 2',5'-ADP | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-2'-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2023-07-12 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120, 2023
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8TG6
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8TG5
| tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with branched 2'-PO4 RNA | Descriptor: | (2S,3R,4R,5S)-2-(6-amino-9H-purin-9-yl)-4-{[(S)-{[(2R,3S,4R,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-({[(S)-{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}(hydroxy)phosphoryl]oxy}methyl)oxolan-3-yl dihydrogen phosphate (non-preferred name), CHLORIDE ION, POTASSIUM ION, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2023-07-12 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120, 2023
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6PPR
| Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and DNA | Descriptor: | ATP-dependent DNA helicase (UvrD/REP), DNA (70-MER), IRON/SULFUR CLUSTER, ... | Authors: | Jia, N, Unciuleac, M, Shuman, S, Patel, D.J. | Deposit date: | 2019-07-08 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection. Proc.Natl.Acad.Sci.USA, 116, 2019
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8DCF
| RNA ligase RtcB from Pyrococcus horikoshii in complex with Cu2+ and GTP | Descriptor: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DCG
| Structure of guanylylated RNA ligase RtcB from Pyrococcus horikoshii | Descriptor: | CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DCD
| RNA ligase RtcB from Pyrococcus horikoshii in complex with Zn2+ and GTP | Descriptor: | CHLORIDE ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DCB
| RNA ligase RtcB from Pyrococcus horikoshii in complex with Ni2+ and GTP | Descriptor: | CHLORIDE ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DCA
| RNA ligase RtcB from Pyrococcus horikoshii in complex with Co2+ and GTP | Descriptor: | COBALT (II) ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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8DC9
| RNA ligase RtcB from Pyrococcus horikoshii in complex with Mn2+ and GTP | Descriptor: | CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2022-06-16 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structures of RNA ligase RtcB in complexes with divalent cations and GTP. Rna, 28, 2022
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6PPJ
| Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP | Descriptor: | ATP-dependent DNA helicase (UvrD/REP), IRON/SULFUR CLUSTER, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Jia, N, Unciuleac, M, Shuman, S, Patel, D.J. | Deposit date: | 2019-07-07 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection. Proc.Natl.Acad.Sci.USA, 116, 2019
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6PPU
| Cryo-EM structure of AdnAB-AMPPNP-DNA complex | Descriptor: | ATP-dependent DNA helicase (UvrD/REP), DNA (29-MER), IRON/SULFUR CLUSTER, ... | Authors: | Jia, N, Unciuleac, M, Shuman, S, Patel, D.J. | Deposit date: | 2019-07-08 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection. Proc.Natl.Acad.Sci.USA, 116, 2019
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1RI1
| Structure and mechanism of mRNA cap (guanine N-7) methyltransferase | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, S-ADENOSYL-L-HOMOCYSTEINE, mRNA CAPPING ENZYME | Authors: | Fabrega, C, Hausmann, S, Shen, V, Shuman, S, Lima, C.D. | Deposit date: | 2003-11-16 | Release date: | 2004-02-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and mechanism of mRNA cap (Guanine-n7) methyltransferase Mol.Cell, 13, 2004
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