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Crystal structure of a murine antibody FAB 528
Descriptor:	CADMIUM ION, CHLORIDE ION, anti egfr antibody fab, ...
Authors:	Nakanishi, T, Tsumoto, K, Asano, R, Kondo, H, Kumagai, I.
Deposit date:	2007-06-22
Release date:	2007-10-30
Last modified:	2024-11-13
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528 J.Biol.Chem., 283, 2008

3SIC

MOLECULAR RECOGNITION AT THE ACTIVE SITE OF SUBTILISIN BPN': CRYSTALLOGRAPHIC STUDIES USING GENETICALLY ENGINEERED PROTEINACEOUS INHIBITOR SSI (STREPTOMYCES SUBTILISIN INHIBITOR)
Descriptor:	CALCIUM ION, STREPTOMYCES SUBTILISIN INHIBITOR (SSI), SUBTILISIN BPN'
Authors:	Mitsui, Y, Takeuchi, Y, Nakamura, K.T.
Deposit date:	1991-08-30
Release date:	1994-01-31
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Molecular recognition at the active site of subtilisin BPN': crystallographic studies using genetically engineered proteinaceous inhibitor SSI (Streptomyces subtilisin inhibitor). Protein Eng., 4, 1991

9IPA

Poly-alanine model for HL-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (open conformation)
Descriptor:	Epidermal growth factor receptor, HL-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain
Authors:	Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y.
Deposit date:	2024-07-10
Release date:	2025-05-28
Last modified:	2025-06-25
Method:	ELECTRON MICROSCOPY (3.85 Å)
Cite:	Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement Cell Rep, 2025

9IPE

Poly-alanine model for LH-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (open conformation)
Descriptor:	Epidermal growth factor receptor, LH-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain
Authors:	Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y.
Deposit date:	2024-07-10
Release date:	2025-05-28
Last modified:	2025-07-02
Method:	ELECTRON MICROSCOPY (3.31 Å)
Cite:	Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement Cell Rep, 2025

9IP8

Poly-alanine model for HL-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (closed conformation)
Descriptor:	Epidermal growth factor receptor, HL-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain
Authors:	Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y.
Deposit date:	2024-07-10
Release date:	2025-05-28
Last modified:	2025-07-02
Method:	ELECTRON MICROSCOPY (3.91 Å)
Cite:	Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement Cell Rep, 2025

9IP9

Poly-alanine model for HL-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (middle conformation)
Descriptor:	Epidermal growth factor receptor, HL-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain
Authors:	Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y.
Deposit date:	2024-07-10
Release date:	2025-05-28
Last modified:	2025-06-18
Method:	ELECTRON MICROSCOPY (3.64 Å)
Cite:	Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement Cell Rep, 2025

9IPC

Poly-alanine model for LH-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (closed conformation)
Descriptor:	Epidermal growth factor receptor, LH-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain
Authors:	Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y.
Deposit date:	2024-07-10
Release date:	2025-05-28
Last modified:	2025-07-02
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement Cell Rep, 2025

9IP7

Local refinement structure of sEGFR and 528 Fv (from HL-type bispecific diabody Ex3) complex
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 528 Fv from HL-type bispecific diabody Ex3, ...
Authors:	Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y.
Deposit date:	2024-07-10
Release date:	2025-05-28
Last modified:	2025-06-25
Method:	ELECTRON MICROSCOPY (3.21 Å)
Cite:	Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement Cell Rep, 2025

9IPD

Poly-alanine model for LH-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (middle conformation)
Descriptor:	Epidermal growth factor receptor, LH-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain
Authors:	Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y.
Deposit date:	2024-07-10
Release date:	2025-05-28
Last modified:	2025-06-18
Method:	ELECTRON MICROSCOPY (3.29 Å)
Cite:	Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement Cell Rep, 2025

9IPB

Local refinement structure of sEGFR and 528 Fv (from LH-type bispecific diabody Ex3) complex
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 528 Fv from LH-type bispecific diabody Ex3, ...
Authors:	Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y.
Deposit date:	2024-07-10
Release date:	2025-05-28
Last modified:	2025-07-02
Method:	ELECTRON MICROSCOPY (2.93 Å)
Cite:	Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement Cell Rep, 2025

5SIC

MOLECULAR RECOGNITION AT THE ACTIVE SITE OF SUBTILISIN BPN': CRYSTALLOGRAPHIC STUDIES USING GENETICALLY ENGINEERED PROTEINACEOUS INHIBITOR SSI (STREPTOMYCES SUBTILISIN INHIBITOR)
Descriptor:	CALCIUM ION, SUBTILISIN BPN', SUBTILISIN INHIBITOR (SSI)
Authors:	Mitsui, Y, Takeuchi, Y, Nakamura, K.T.
Deposit date:	1991-11-18
Release date:	1994-01-31
Last modified:	2024-11-13
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Molecular recognition at the active site of subtilisin BPN': crystallographic studies using genetically engineered proteinaceous inhibitor SSI (Streptomyces subtilisin inhibitor). Protein Eng., 4, 1991

6KR0

Crystal structure of HL homo-diabody
Descriptor:	HL diabody
Authors:	Tanaka, Y.
Deposit date:	2019-08-20
Release date:	2020-08-26
Last modified:	2024-11-06
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Association behavior and control of the quality of cancer therapeutic bispecific diabodies expressed in Escherichia coli Biochem Eng J, 160, 2020

1QQY

X-RAY CRYSTAL STRUCTURE ANALYSIS OF CANINE MILK LYSOZYME (APO-TYPE)
Descriptor:	LYSOZYME C
Authors:	Koshiba, T, Yao, M, Tanaka, I, Nitta, K.
Deposit date:	1999-06-09
Release date:	2000-06-09
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structure and thermodynamics of the extraordinarily stable molten globule state of canine milk lysozyme. Biochemistry, 39, 2000

1EL1

X-RAY CRYSTAL STRUCTURE ANALYSIS OF CANINE MILK LYSOZYME (HOLO-TYPE)
Descriptor:	CALCIUM ION, LYSOZYME C
Authors:	Koshiba, T, Yao, M, Tanaka, I, Nitta, K.
Deposit date:	2000-03-13
Release date:	2001-03-13
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Calcium Induced Conformational Changes of Canine Milk Lysozyme Revealed by Structural and Thermodynamical Evidences To be Published

2E27

Crystal structure of Fv fragment of anti-ciguatoxin antibody complexed with ABC-ring of ciguatoxin
Descriptor:	3,7:6,10:9,14-TRIANHYDRO-2,5,11,12,13-PENTADEOXY-4-O-(METHOXYMETHYL)-L-ARABINO-L-ALLO-TETRADEC-12-ENONIC ACID, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:	Yokota, A, Tanaka, Y, Tsumoto, K.
Deposit date:	2006-11-08
Release date:	2007-11-13
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49. J.Biol.Chem., 283, 2008

2D7T

Crystal structure of human anti polyhydroxybutyrate antibody Fv
Descriptor:	anti polyhydroxybutyrate antibody Fv, heavy chain, light chain
Authors:	Watanabe, H.
Deposit date:	2005-11-29
Release date:	2006-12-12
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	A human antibody fragment with high affinity for the biodegradable polymer film To be Published

2DYP

Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G
Descriptor:	9 Mer Peptide From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:	Shiroishi, M, Kuroki, K, Rasubala, L, Kohda, D, Maenaka, K.
Deposit date:	2006-09-15
Release date:	2006-11-07
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d) Proc.Natl.Acad.Sci.Usa, 103, 2006

2E7D

Crystal structure of a NEAT domain from Staphylococcus aureus
Descriptor:	ACETATE ION, GLYCEROL, Hypothetical protein IsdH, ...
Authors:	Suenaga, A, Tanaka, Y, Yao, M, Kumagai, I, Tanaka, I, Tsumoto, K.
Deposit date:	2007-01-09
Release date:	2008-01-22
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structural basis for multimeric heme complexation through a specific protein-heme interaction: the case of the third neat domain of IsdH from Staphylococcus aureus J.Biol.Chem., 283, 2008

2ZIJ

Crystal Structure of Human Lysozyme Expressed in E. coli.
Descriptor:	Lysozyme C, SODIUM ION
Authors:	Tamada, T, Kuroki, R, Koshiba, T.
Deposit date:	2008-02-18
Release date:	2009-01-06
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Preparation and characterization of methyonyl-lysine attached human lysozyme expressed in Escherichia coli and its effective conversion to the authentic-like protein To be Published

2ZIK

Crystal Structure of Human Lysozyme from Pichia pastoris
Descriptor:	Lysozyme C, SODIUM ION
Authors:	Tamada, T, Kuroki, R, Koshiba, T.
Deposit date:	2008-02-18
Release date:	2009-01-06
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (1.81 Å)
Cite:	Preparation and characterization of methyonyl-lysine attached human lysozyme expressed in Escherichia coli and its effective conversion to the authentic-like protein To be Published

2ZIL

Crystal Structure of Human Lysozyme from Urine
Descriptor:	Lysozyme C, SODIUM ION
Authors:	Tamada, T, Kuroki, R, Koshiba, T.
Deposit date:	2008-02-18
Release date:	2009-01-06
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Preparation and characterization of methyonyl-lysine attached human lysozyme expressed in Escherichia coli and its effective conversion to the authentic-like protein To be Published

3SSI

PROTEINASE INHIBITOR SSI (STREPTOMYCES SUBTILISIN, INHIBITOR) FROM STREPTOMYCES ALBOGRISEOLUS
Descriptor:	STREPTOMYCES SUBTILISIN INHIBITOR
Authors:	Suzuki, T, Nonaka, T, Mitsui, Y.
Deposit date:	1996-03-01
Release date:	1996-08-17
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structural Modulation of the Protein Proteinase Inhibitor Ssi (Streptomyces Subtilisin Inhibitor) To be Published

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