5GMQ
| Structure of MERS-CoV RBD in complex with a fully human antibody MCA1 | Descriptor: | 1,2-ETHANEDIOL, MCA1 heavy chain, MCA1 light chain, ... | Authors: | Chen, C, Wang, J.M, Zou, T.T, Gao, X.P, Cui, S, Jin, Q. | Deposit date: | 2016-07-15 | Release date: | 2017-05-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset. J. Infect. Dis., 215, 2017
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6UHX
| Crystal structure of YIR035C short chain dehydrogenases/reductase from Saccharomyces cerevisiae | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized oxidoreductase YIR035C | Authors: | Stogios, P.J, Skarina, T, Chen, C, Kagan, O, Iakounine, A, Savchenko, A. | Deposit date: | 2019-09-29 | Release date: | 2020-08-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of YIR035C short chain dehydrogenases/reductase from Saccharomyces cerevisiae To Be Published
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5C94
| Infectious bronchitis virus nsp9 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Non-structural protein 9 | Authors: | Chen, C, Dou, Y, Yang, H, Su, D. | Deposit date: | 2015-06-26 | Release date: | 2016-06-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.438 Å) | Cite: | Structural basis for dimerization and RNA binding of avian infectious bronchitis virus nsp9. Protein Sci., 26, 2017
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5TPK
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3W9S
| Crystal Structure Analysis of the N-terminal Receiver domain of Response Regulator PmrA | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, OmpR family response regulator in two-component regulatory system with BasS | Authors: | Chen, C, Luo, S. | Deposit date: | 2013-04-15 | Release date: | 2013-07-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of a Physical Blockage Mechanism for the Interaction of Response Regulator PmrA with Connector Protein PmrD from Klebsiella Pneumoniae J.Biol.Chem., 288, 2013
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4LRH
| Crystal structure of human folate receptor alpha in complex with folic acid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, Folate receptor alpha | Authors: | Ke, J, Chen, C, Zhou, X.E, Yi, W, Brunzelle, J.S, Li, J, Young, E.-L, Xu, H.E, Melcher, K. | Deposit date: | 2013-07-19 | Release date: | 2013-07-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for molecular recognition of folic acid by folate receptors. Nature, 500, 2013
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3M0K
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3M0J
| Structure of oxaloacetate acetylhydrolase in complex with the inhibitor 3,3-difluorooxalacetate | Descriptor: | 2,2-difluoro-3,3-dihydroxybutanedioic acid, CALCIUM ION, MANGANESE (II) ION, ... | Authors: | Herzberg, O, Chen, C. | Deposit date: | 2010-03-03 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure of oxalacetate acetylhydrolase, a virulence factor of the chestnut blight fungus. J.Biol.Chem., 285, 2010
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6A4C
| Solution structure of MXAN_0049 | Descriptor: | Uncharacterized protein MXAN_0049 | Authors: | Chen, C, Feng, Y. | Deposit date: | 2018-06-19 | Release date: | 2019-06-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of MXAN_0049 To Be Published
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3LYE
| Crystal structure of oxaloacetate acetylhydrolase | Descriptor: | CALCIUM ION, Oxaloacetate acetyl hydrolase | Authors: | Herzberg, O, Chen, C. | Deposit date: | 2010-02-26 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure of oxalacetate acetylhydrolase, a virulence factor of the chestnut blight fungus. J.Biol.Chem., 285, 2010
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2LNM
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3QYM
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5X8Y
| A Mutation identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in vitro | Descriptor: | ZIKV NS1 | Authors: | Wang, D, Chen, C, Liu, S, Zhou, H, Yang, K, Zhao, Q, Ji, X, Chen, C, Xie, W, Wang, Z, Mi, L.Z, Yang, H. | Deposit date: | 2017-03-03 | Release date: | 2017-05-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.817 Å) | Cite: | A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro Sci Rep, 7, 2017
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5JMT
| Crystal structure of Zika virus NS3 helicase | Descriptor: | NS3 helicase | Authors: | Tian, H, Ji, X, Yang, X, Xie, W, Yang, K, Chen, C, Wu, C, Chi, H, Mu, Z, Wang, Z, Yang, H. | Deposit date: | 2016-04-29 | Release date: | 2016-05-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.796 Å) | Cite: | The crystal structure of Zika virus helicase: basis for antiviral drug design Protein Cell, 7, 2016
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4MY2
| Crystal Structure of Norrin in fusion with Maltose Binding Protein | Descriptor: | Maltose-binding periplasmic protein, Norrin fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Ke, J, Jurecky, C, Chen, C, Gu, X, Parker, N, Williams, B.O, Melcher, K, Xu, H.E. | Deposit date: | 2013-09-27 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex. Genes Dev., 27, 2013
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3LD1
| Crystal Structure of IBV Nsp2a | Descriptor: | Replicase polyprotein 1a | Authors: | Xu, Y, Cong, L, Wei, L, Fu, J, Chen, C, Yang, A, Tang, H, Bartlam, M, Rao, Z. | Deposit date: | 2010-01-12 | Release date: | 2011-05-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | IBV nsp2 is an endosome-associated protein and viral pathogenicity factor To be Published
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6DXK
| Glucocorticoid Receptor in complex with Compound 11 | Descriptor: | (8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-(3,3-dimethylbut-1-yn-1-yl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name), Glucocorticoid receptor | Authors: | Rew, Y, Du, X, Eksterowicz, J, Zhou, H, Jahchan, N, Zhu, L, Yan, X, Kawai, H, McGee, L.R, Medina, J.C, Huang, T, Chen, C, Zavorotinskaya, T, Sutimantanapi, D, Waszczuk, J, Jackson, E, Huang, E, Ye, Q, Fantin, V.R, Daqing, S. | Deposit date: | 2018-06-29 | Release date: | 2018-10-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101). J. Med. Chem., 61, 2018
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8X7A
| Treprostinil bound Prostacyclin Receptor G protein complex | Descriptor: | 2-[[(1~{R},2~{R},3~{a}~{S},9~{a}~{S})-2-oxidanyl-1-[(3~{S})-3-oxidanyloctyl]-2,3,3~{a},4,9,9~{a}-hexahydro-1~{H}-cyclopenta[g]naphthalen-5-yl]oxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, J.J, Jin, S, Zhang, H, Xu, Y, Hu, W, Jiang, Y, Chen, C, Wang, D.W, Xu, H.E, Wu, C. | Deposit date: | 2023-11-23 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs. Sci Adv, 10, 2024
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8X79
| MRE-269 bound Prostacyclin Receptor G protein complex | Descriptor: | 2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-yl-amino]butoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, J.J, Jin, S, Zhang, H, Xu, Y, Hu, W, Jiang, Y, Chen, C, Wang, D.W, Xu, H.E, Wu, C. | Deposit date: | 2023-11-23 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.41 Å) | Cite: | Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs. Sci Adv, 10, 2024
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6KZ6
| Crystal structure of ASFV dUTPase | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R, MAGNESIUM ION | Authors: | Guo, Y, Chen, C, Li, G.B, Cao, L, Wang, C.W. | Deposit date: | 2019-09-23 | Release date: | 2019-11-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.187 Å) | Cite: | Structural Insight into African Swine Fever Virus dUTPase Reveals a Novel Folding Pattern in the dUTPase Family. J.Virol., 94, 2020
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4TOS
| Crystal structure of Tankyrase 1 with 355 | Descriptor: | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide | Authors: | Chen, H, Zhang, X, Lum, l, Chen, C. | Deposit date: | 2014-06-06 | Release date: | 2015-05-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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6LJ9
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6LJB
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1Z5F
| Solution Structure of the Cytotoxic RC-RNase 3 with a Pyroglutamate Residue at the N-terminus | Descriptor: | RC-RNase 3 | Authors: | Lou, Y.C, Huang, Y.C, Pan, Y.R, Chen, C, Liao, Y.D. | Deposit date: | 2005-03-18 | Release date: | 2006-02-28 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Roles of N-terminal pyroglutamate in maintaining structural integrity and pKa values of catalytic histidine residues in bullfrog ribonuclease 3 J.Mol.Biol., 355, 2006
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1KVZ
| Solution Structure of Cytotoxic RC-RNase4 | Descriptor: | RC-RNase4 | Authors: | Hsu, C.-H, Liao, Y.-D, Chen, L.-W, Wu, S.-H, Chen, C. | Deposit date: | 2002-01-28 | Release date: | 2002-07-28 | Last modified: | 2022-12-21 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Cytotoxic RNase 4 from the Oocytes of Bullfrog Rana Catesbeiana J.MOL.BIOL., 326, 2003
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