3DAU
 
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7V6Y
 | | Cryo-EM structure of Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed with dataset of 7dzq) | | Descriptor: | (2S)-2-azanyl-3-[[(2S)-3-butanoyloxy-2-dec-9-enoyloxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Luo, Y, Zhao, Y, Qu, Q, Li, D. | | Deposit date: | 2021-08-20 | | Release date: | 2021-09-22 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM study of patched in lipid nanodisc suggests a structural basis for its clustering in caveolae.
Structure, 29, 2021
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7V6Z
 | | Cryo-EM structure of Patched1 (V1084A mutant) in lipid nanodisc, 3.64 angstrom (reprocessed with the dataset of 7dzp) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Luo, Y, Zhao, Y, Qu, Q, Li, D. | | Deposit date: | 2021-08-20 | | Release date: | 2021-09-22 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Cryo-EM study of patched in lipid nanodisc suggests a structural basis for its clustering in caveolae.
Structure, 29, 2021
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5J1A
 | | Antigen presenting molecule | | Descriptor: | 3-[(8Z,11Z)-pentadeca-8,11-dien-1-yl]benzene-1,2-diol, Beta-2-microglobulin, T-cell surface glycoprotein CD1a | | Authors: | Yongqing, T, Rossjohn, J, Le Nours, J, Marquez, E, Winau, F. | | Deposit date: | 2016-03-29 | | Release date: | 2016-08-03 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | CD1a on Langerhans cells controls inflammatory skin disease.
Nat. Immunol., 17, 2016
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7DVM
 | | DgkA structure in E.coli lipid bilayer | | Descriptor: | Diacylglycerol kinase | | Authors: | Li, J, Yang, J. | | Deposit date: | 2021-01-13 | | Release date: | 2022-04-13 | | Last modified: | 2023-09-27 | | Method: | SOLID-STATE NMR | | Cite: | Structure of membrane diacylglycerol kinase in lipid bilayers.
Commun Biol, 4, 2021
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4TW2
 | | Crystal Structure of SCARB2 in Neural Condition (pH7.5) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Scavenger receptor class B member 2, ... | | Authors: | Dang, M.H, Wang, X.X, Rao, Z.H. | | Deposit date: | 2014-06-29 | | Release date: | 2015-07-08 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.889 Å) | | Cite: | Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71
Protein Cell, 5, 2014
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8HZ8
 | | Structure of PPIA in complex with the peptide of NRF2 | | Descriptor: | NRF2 peptide, Peptidyl-prolyl cis-trans isomerase A, N-terminally processed | | Authors: | Wanyan, W, Hui, M, Jin, H, Lu, W. | | Deposit date: | 2023-01-08 | | Release date: | 2024-03-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | PPIA dictates NRF2 stability to promote lung cancer progression.
Nat Commun, 15, 2024
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4TXS
 | | An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | | Descriptor: | (4-hydroxyphenyl)acetonitrile, Polyprotein | | Authors: | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | | Deposit date: | 2014-07-07 | | Release date: | 2015-05-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline
Sci Rep, 5, 2015
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4TY8
 | | An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | | Descriptor: | 6-methyl-2H-chromen-2-one, Polyprotein | | Authors: | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | | Deposit date: | 2014-07-08 | | Release date: | 2015-05-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline
Sci Rep, 5, 2015
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6W51
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9KYQ
 | | GH57 family amylopullulanase from Aquifex aeolicus wild type co-crystallize with gama-cyclodextrin | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Zhu, Z.M, Wang, W.W, Yu, F, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S. | | Deposit date: | 2024-12-09 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Mechanistic insights into cyclodextrins as substrates and inhibitors of GH57 family amylopullulanase from Aquifex aeolicus.
J.Struct.Biol., 217, 2025
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9KYP
 | | GH57 family amylopullulanase from Aquifex aeolicus wild type complex with beta-cyclodextrin | | Descriptor: | 1,2-ETHANEDIOL, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), DI(HYDROXYETHYL)ETHER, ... | | Authors: | Zhu, Z.M, Wang, W.W, Yu, F, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S. | | Deposit date: | 2024-12-09 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Mechanistic insights into cyclodextrins as substrates and inhibitors of GH57 family amylopullulanase from Aquifex aeolicus.
J.Struct.Biol., 217, 2025
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9K7C
 | | Crystal structure of GH57 family amylopullulanase from Aquifex aeolicus mutant E256Q in complex with maltopentaose | | Descriptor: | GLYCEROL, Glycoside hydrolase family 57 N-terminal domain-containing protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | Authors: | Zhu, Z.M, Wang, W.W, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S, Yu, F. | | Deposit date: | 2024-10-23 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The crystal structure of GH57 family amylopullulanase reveals its dual binding pockets sharing the same catalytic dyad.
Commun Biol, 8, 2025
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9KYR
 | | GH57 family amylopullulanase from Aquifex aeolicus D352N mutant complex with gama-cyclodextrin | | Descriptor: | 1,2-ETHANEDIOL, Cyclooctakis-(1-4)-(alpha-D-glucopyranose), DI(HYDROXYETHYL)ETHER, ... | | Authors: | Zhu, Z.M, Wang, W.W, Yu, F, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S. | | Deposit date: | 2024-12-09 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Mechanistic insights into cyclodextrins as substrates and inhibitors of GH57 family amylopullulanase from Aquifex aeolicus.
J.Struct.Biol., 217, 2025
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9K7D
 | | Crystal structure of GH57 family amylopullulanase from Aquifex aeolicus mutant E256Q in complex with Maltohexaose | | Descriptor: | Glycoside hydrolase family 57 N-terminal domain-containing protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Zhu, Z.M, Wang, W.W, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S, Yu, F. | | Deposit date: | 2024-10-23 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | The crystal structure of GH57 family amylopullulanase reveals its dual binding pockets sharing the same catalytic dyad.
Commun Biol, 8, 2025
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9JLW
 | | Crystal structure of GH57 family amylopullulanase from Aquifex aeolicus mutant D352N in complex with maltoheptaose | | Descriptor: | GLYCEROL, Glycoside hydrolase family 57 N-terminal domain-containing protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | Authors: | Zhu, Z.M, Wang, W.W, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S, Yu, F. | | Deposit date: | 2024-09-19 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | High-Temperature Crystallization Method for the GH57 Family Hyperthermophilic Amylopullulanase from Aquifex aeolicus
Cryst.Growth Des., 24, 2024
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9JLU
 | | GH57 family amylopullulanase from Aquifex aeolicus D352N mutant complex with beta-cyclodextrin | | Descriptor: | Cycloheptakis-(1-4)-(alpha-D-glucopyranose), GLYCEROL, Glycoside hydrolase family 57 N-terminal domain-containing protein | | Authors: | Zhu, Z.M, Wang, W.W, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S, Yu, F. | | Deposit date: | 2024-09-19 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Mechanistic insights into cyclodextrins as substrates and inhibitors of GH57 family amylopullulanase from Aquifex aeolicus.
J.Struct.Biol., 217, 2025
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9JLR
 | | Crystal structure of GH57 family amylopullulanase from Aquifex aeolicus mutant E256Q in complex with maltopentaose | | Descriptor: | Glycoside hydrolase family 57 N-terminal domain-containing protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Zhu, Z.M, Wang, W.W, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S, Yu, F. | | Deposit date: | 2024-09-19 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | High-Temperature Crystallization Method for the GH57 Family Hyperthermophilic Amylopullulanase from Aquifex aeolicus
Cryst.Growth Des., 24, 2024
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9JLS
 | | Crystal structure of GH57 family amylopullulanase from Aquifex aeolicus wild type in complex with acarbose | | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Glycoside hydrolase family 57 N-terminal domain-containing protein | | Authors: | Zhu, Z.M, Wang, W.W, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S, Yu, F. | | Deposit date: | 2024-09-19 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (3.06 Å) | | Cite: | High-Temperature Crystallization Method for the GH57 Family Hyperthermophilic Amylopullulanase from Aquifex aeolicus
Cryst.Growth Des., 24, 2024
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9JLV
 | | Crystal structure of GH57 family amylopullulanase from Aquifex aeolicus mutant E256Q in complex with alpha-cyclodextrin | | Descriptor: | CITRATE ANION, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), GLYCEROL, ... | | Authors: | Zhu, Z.M, Wang, W.W, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S, Yu, F. | | Deposit date: | 2024-09-19 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Mechanistic insights into cyclodextrins as substrates and inhibitors of GH57 family amylopullulanase from Aquifex aeolicus.
J.Struct.Biol., 217, 2025
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9JLT
 | | GH57 family amylopullulanase D352N mutant from Aquifex aeolicus complex with alpha-cyclodextrin | | Descriptor: | Cyclohexakis-(1-4)-(alpha-D-glucopyranose), GLYCEROL, Glycoside hydrolase family 57 N-terminal domain-containing protein | | Authors: | Zhu, Z.M, Wang, W.W, Li, M.J, Xu, Q, Zhou, H, Huang, L.Q, Wang, Q.S, Yu, F. | | Deposit date: | 2024-09-19 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Mechanistic insights into cyclodextrins as substrates and inhibitors of GH57 family amylopullulanase from Aquifex aeolicus.
J.Struct.Biol., 217, 2025
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8ZYI
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9BLL
 | | Cryo-EM of RBD(EG5.1)/1301B7 Fab Complex | | Descriptor: | 1301B7 Heavy Chain, 1301B7 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Walter, M.R, Green, T.J. | | Deposit date: | 2024-04-30 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Potent neutralization by a RBD antibody with broad specificity for SARS-CoV-2 JN.1 and other variants.
Npj Viruses, 2, 2024
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3S5L
 | | Crystal structure of CD4 mutant bound to HLA-DR1 | | Descriptor: | GLYCEROL, HA peptide, HLA class II histocompatibility antigen DR beta chain, ... | | Authors: | Li, Y. | | Deposit date: | 2011-05-23 | | Release date: | 2011-09-21 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3S4S
 | | Crystal structure of CD4 mutant bound to HLA-DR1 | | Descriptor: | GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ... | | Authors: | Li, Y. | | Deposit date: | 2011-05-20 | | Release date: | 2011-09-21 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
Proc.Natl.Acad.Sci.USA, 108, 2011
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