6QET
 
 | | [41-82]Gga-AvBD11 | | Descriptor: | Gallinacin-11 | | Authors: | Meudal, H, Loth, K, Delmas, A.F, Landon, C. | | Deposit date: | 2019-01-08 | | Release date: | 2019-12-18 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure, function, and evolution ofGga-AvBD11, the archetype of the structural avian-double-beta-defensin family.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6QEU
 | | Gga-AvBD11 (Avian beta-defensin 11 from Gallus gallus) | | Descriptor: | Gallinacin-11 | | Authors: | Meudal, H, Loth, K, Delmas, A.F, Landon, C. | | Deposit date: | 2019-01-08 | | Release date: | 2019-12-18 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure, function, and evolution ofGga-AvBD11, the archetype of the structural avian-double-beta-defensin family.
Proc.Natl.Acad.Sci.USA, 117, 2020
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1NLR
 | | ENDO-1,4-BETA-GLUCANASE CELB2, CELLULASE, NATIVE STRUCTURE | | Descriptor: | ENDO-1,4-BETA-GLUCANASE | | Authors: | Sulzenbacher, G, Dupont, C, Davies, G.J. | | Deposit date: | 1997-10-27 | | Release date: | 1998-11-25 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The Streptomyces lividans family 12 endoglucanase: construction of the catalytic cre, expression, and X-ray structure at 1.75 A resolution.
Biochemistry, 36, 1997
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6SKY
 | | FAT and kinase domain of CtTel1 | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | Authors: | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | Deposit date: | 2019-08-16 | | Release date: | 2019-10-30 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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6SL0
 | | Complete CtTel1 dimer with C2 symmetry | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | Authors: | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | Deposit date: | 2019-08-16 | | Release date: | 2019-10-30 | | Last modified: | 2020-01-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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6HJW
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6SKZ
 | | Structure of the closed conformation of CtTel1 | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | Authors: | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | Deposit date: | 2019-08-16 | | Release date: | 2019-10-30 | | Last modified: | 2020-01-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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6SL1
 | | Structure of the open conformation of CtTel1 | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | Authors: | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | Deposit date: | 2019-08-16 | | Release date: | 2019-10-30 | | Last modified: | 2020-05-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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6O0A
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1R74
 | | Crystal Structure of Human Glycine N-Methyltransferase | | Descriptor: | BETA-MERCAPTOETHANOL, CITRIC ACID, Glycine N-methyltransferase | | Authors: | Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E. | | Deposit date: | 2003-10-17 | | Release date: | 2004-09-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
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1R8X
 | | Crystal Structure of Mouse Glycine N-Methyltransferase (Tetragonal Form) | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, glycine N-methyltransferase | | Authors: | Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E. | | Deposit date: | 2003-10-28 | | Release date: | 2004-09-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
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2AMV
 | | THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID | | Descriptor: | 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM, GLYCEROL, PROTEIN (GLYCOGEN PHOSPHORYLASE), ... | | Authors: | Zographos, S.E, Oikonomakos, N.G, Johnson, L.N. | | Deposit date: | 1998-10-13 | | Release date: | 1998-10-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor.
Structure, 5, 1997
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2N2J
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5M5E
 | | Crystal structure of a interleukin-2 variant in complex with interleukin-2 receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Klein, C, Freimoser-Grundschober, A, Waldhauer, I, Stihle, M, Birk, M, Benz, J. | | Deposit date: | 2016-10-21 | | Release date: | 2017-05-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines.
Oncoimmunology, 6, 2017
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6NZM
 | | Brutons tyrosine kinase in complex with compound 50. | | Descriptor: | 1,2-ETHANEDIOL, N-[2-fluoro-6-(pyrrolidin-1-yl)phenyl]-N'-{3-[(2R)-1-(2-hydroxyethyl)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl]phenyl}urea, Tyrosine-protein kinase BTK | | Authors: | Marcotte, D.J. | | Deposit date: | 2019-02-14 | | Release date: | 2019-06-12 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Optimization of novel reversible Bruton's tyrosine kinase inhibitors identified using Tethering-fragment-based screens.
Bioorg.Med.Chem., 27, 2019
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1B9N
 | | REGULATOR FROM ESCHERICHIA COLI | | Descriptor: | NICKEL (II) ION, PROTEIN (MODE) | | Authors: | Hall, D.R, Gourley, D.G, Hunter, W.N. | | Deposit date: | 1999-02-12 | | Release date: | 2000-03-15 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds.
EMBO J., 18, 1999
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1B9M
 | | REGULATOR FROM ESCHERICHIA COLI | | Descriptor: | NICKEL (II) ION, PROTEIN (MODE) | | Authors: | Hall, D.R, Gourley, D.G, Hunter, W.N. | | Deposit date: | 1999-02-12 | | Release date: | 2000-03-15 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds.
EMBO J., 18, 1999
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2KMU
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2K5O
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5OR6
 | | Crystal structures of PYR1/HAB1 in complex with synthetic analogues of Abscisic Acid | | Descriptor: | (~{E})-3-(trifluoromethyl)-5-[(1~{S})-2,6,6-trimethyl-1-oxidanyl-4-oxidanylidene-cyclohex-2-en-1-yl]pent-2-en-4-ynoic acid, Abscisic acid receptor PYR1, MANGANESE (II) ION, ... | | Authors: | Freigang, J. | | Deposit date: | 2017-08-15 | | Release date: | 2018-06-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Insights into the in Vitro and in Vivo SAR of Abscisic Acid - Exploring Unprecedented Variations of the Side Chain via Cross-Coupling-Mediated Syntheses
Eur.J.Org.Chem., 2018
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5OR2
 | | Crystal structures of PYR1/HAB1 in complex with synthetic analogues of Abscisic Acid | | Descriptor: | (2~{Z},4~{E})-3-cyclopropyl-5-[(1~{S})-2,6,6-trimethyl-1-oxidanyl-4-oxidanylidene-cyclohex-2-en-1-yl]penta-2,4-dienoic acid, Abscisic acid receptor PYR1, MANGANESE (II) ION, ... | | Authors: | Freigang, J. | | Deposit date: | 2017-08-15 | | Release date: | 2018-06-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Insights into the in Vitro and in Vivo SAR of Abscisic Acid - Exploring Unprecedented Variations of the Side Chain via Cross-Coupling-Mediated Syntheses
Eur.J.Org.Chem., 2018
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7AO7
 | | Structure of CYP153A from Polaromonas sp. in complex with octan-1-ol | | Descriptor: | Cytochrome P450, OCTAN-1-OL, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Zukic, E, Rowlinson, B, Sharma, M, Hoffmann, S, Hauer, B, Grogan, G. | | Deposit date: | 2020-10-13 | | Release date: | 2021-04-07 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Substrate Anchoring and Flexibility Reduction in CYP153AM.aq Leads to Highly Improved Efficiency toward Octanoic Acid
Acs Catalysis, 11, 2021
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7QJ5
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7QJD
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7QJ2
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