2Q8I
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![BU of 2q8i by Molmil](/molmil-images/mine/2q8i) | Pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug radicicol | Descriptor: | DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, GLYCEROL, ... | Authors: | Kato, M, Li, J, Chuang, J.L, Chuang, D.T. | Deposit date: | 2007-06-10 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
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1B34
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![BU of 1b34 by Molmil](/molmil-images/mine/1b34) | CRYSTAL STRUCTURE OF THE D1D2 SUB-COMPLEX FROM THE HUMAN SNRNP CORE DOMAIN | Descriptor: | PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1), PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2) | Authors: | Walke, S, Young, R.J, Kambach, C, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | Deposit date: | 1998-12-17 | Release date: | 2000-01-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell(Cambridge,Mass.), 96, 1999
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6KOE
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![BU of 6koe by Molmil](/molmil-images/mine/6koe) | X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis | Descriptor: | 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, ... | Authors: | Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J. | Deposit date: | 2019-08-09 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.75 Å) | Cite: | Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site. Proc.Natl.Acad.Sci.USA, 117, 2020
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2Q8H
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![BU of 2q8h by Molmil](/molmil-images/mine/2q8h) | Structure of pyruvate dehydrogenase kinase isoform 1 in complex with dichloroacetate (DCA) | Descriptor: | DICHLORO-ACETIC ACID, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 | Authors: | Kato, M, Li, J, Chuang, J.L, Chuang, D.T. | Deposit date: | 2007-06-10 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
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6KOC
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![BU of 6koc by Molmil](/molmil-images/mine/6koc) | X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis complexed with 3-iodo-N-oxo-2-heptyl-4-hydroxyquinoline | Descriptor: | 2-heptyl-3-iodanyl-1-oxidanyl-quinolin-4-one, AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, ... | Authors: | Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J. | Deposit date: | 2019-08-09 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site. Proc.Natl.Acad.Sci.USA, 117, 2020
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4BGD
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![BU of 4bgd by Molmil](/molmil-images/mine/4bgd) | Crystal structure of Brr2 in complex with the Jab1/MPN domain of Prp8 | Descriptor: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nguyen, T.H.D, Li, J, Nagai, K. | Deposit date: | 2013-03-25 | Release date: | 2013-05-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Basis of Brr2-Prp8 Interactions and Implications for U5 Snrnp Biogenesis and the Spliceosome Active Site Structure, 21, 2013
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6KOB
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![BU of 6kob by Molmil](/molmil-images/mine/6kob) | X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis | Descriptor: | AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, AA3-600 quinol oxidase subunit IV,Quinol oxidase subunit 4, ... | Authors: | Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J. | Deposit date: | 2019-08-09 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site. Proc.Natl.Acad.Sci.USA, 117, 2020
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2Q8F
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![BU of 2q8f by Molmil](/molmil-images/mine/2q8f) | Structure of pyruvate dehydrogenase kinase isoform 1 | Descriptor: | POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 | Authors: | Kato, M, Li, J, Chuang, J.L, Chuang, D.T. | Deposit date: | 2007-06-10 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
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3UOT
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![BU of 3uot by Molmil](/molmil-images/mine/3uot) | Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus | Descriptor: | Mediator of DNA damage checkpoint protein 1 | Authors: | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | Deposit date: | 2011-11-17 | Release date: | 2011-12-28 | Last modified: | 2012-07-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
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1W2X
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![BU of 1w2x by Molmil](/molmil-images/mine/1w2x) | Crystal structure of the carboxyltransferase domain of acetyl- coenzyme A carboxylase in complex with CP-640186 | Descriptor: | (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE, ACETYL-COA CARBOXYLASE | Authors: | Zhang, H, Tweel, B, Li, J, Tong, L. | Deposit date: | 2004-07-09 | Release date: | 2004-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Carboxyltransferase Domain of Acetyl-Coenzyme a Carboxylase in Complex with Cp-640186 Structure, 12, 2004
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2Q8G
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![BU of 2q8g by Molmil](/molmil-images/mine/2q8g) | Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545 | Descriptor: | 4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 | Authors: | Kato, M, Li, J, Chuang, J.L, Chuang, D.T. | Deposit date: | 2007-06-10 | Release date: | 2007-07-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
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6P49
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![BU of 6p49 by Molmil](/molmil-images/mine/6p49) | Cryo-EM structure of calcium-bound TMEM16F in nanodisc with supplement of PIP2 in Cl2 | Descriptor: | Anoctamin-6, CALCIUM ION | Authors: | Feng, S, Dang, S, Han, T.W, Ye, W, Jin, P, Cheng, T, Li, J, Jan, Y.N, Jan, L.Y, Cheng, Y. | Deposit date: | 2019-05-26 | Release date: | 2019-07-24 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling. Cell Rep, 28, 2019
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2R2N
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![BU of 2r2n by Molmil](/molmil-images/mine/2r2n) | The crystal structure of human kynurenine aminotransferase II in complex with kynurenine | Descriptor: | (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLYCEROL, ... | Authors: | Han, Q, Robinson, H, Li, J. | Deposit date: | 2007-08-27 | Release date: | 2007-12-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of human kynurenine aminotransferase II. J.Biol.Chem., 283, 2008
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2QTW
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![BU of 2qtw by Molmil](/molmil-images/mine/2qtw) | The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, ... | Authors: | Hampton, E.N, Knuth, M.W, Li, J, Harris, J.L, Lesley, S.A, Spraggon, G. | Deposit date: | 2007-08-02 | Release date: | 2007-09-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain. Proc.Natl.Acad.Sci.Usa, 104, 2007
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5ET0
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![BU of 5et0 by Molmil](/molmil-images/mine/5et0) | Crystal structure of Myo3b-ARB2 in complex with Espin1-AR | Descriptor: | Espin, Myosin-IIIb | Authors: | Liu, H, Li, J, Liu, W, Zhang, M. | Deposit date: | 2015-11-17 | Release date: | 2016-02-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin Elife, 5, 2016
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5ET1
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![BU of 5et1 by Molmil](/molmil-images/mine/5et1) | Crystal structure of Myo3b-ARB1 in complex with Espin1-AR | Descriptor: | Espin, GLYCEROL, Myosin-IIIb | Authors: | Liu, H, Li, J, liu, W, Zhang, M. | Deposit date: | 2015-11-17 | Release date: | 2016-02-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin Elife, 5, 2016
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3KB3
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![BU of 3kb3 by Molmil](/molmil-images/mine/3kb3) | Crystal structure of abscisic acid-bound PYL2 in complex with HAB1 | Descriptor: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, MAGNESIUM ION, Protein phosphatase 2C 16, ... | Authors: | Zhou, X.E, Melcher, K, Soon, F.-F, Ng, L.-M, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E. | Deposit date: | 2009-10-20 | Release date: | 2009-12-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors Nature, 462, 2009
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1D3B
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![BU of 1d3b by Molmil](/molmil-images/mine/1d3b) | CRYSTAL STRUCTURE OF THE D3B SUBCOMPLEX OF THE HUMAN CORE SNRNP DOMAIN AT 2.0A RESOLUTION | Descriptor: | CITRIC ACID, GLYCEROL, PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN ASSOCIATED PROTEIN B), ... | Authors: | Kambach, C, Walke, S, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | Deposit date: | 1998-12-22 | Release date: | 1999-12-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell(Cambridge,Mass.), 96, 1999
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4E15
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![BU of 4e15 by Molmil](/molmil-images/mine/4e15) | |
2R5E
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![BU of 2r5e by Molmil](/molmil-images/mine/2r5e) | Aedes kynurenine aminotransferase in complex with glutamine | Descriptor: | Kynurenine aminotransferase, N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-GLUTAMINE | Authors: | Han, Q, Gao, Y.G, Robinson, H, Li, J. | Deposit date: | 2007-09-03 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase. Biochemistry, 47, 2008
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6JMK
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![BU of 6jmk by Molmil](/molmil-images/mine/6jmk) | Ribosomal protein S7 from Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, 30S ribosomal protein S7, GLYCEROL | Authors: | Li, Z, Li, J. | Deposit date: | 2019-03-11 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into the complex of trigger factor chaperone and ribosomal protein S7 from Mycobacterium tuberculosis. Biochem. Biophys. Res. Commun., 512, 2019
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4NXE
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![BU of 4nxe by Molmil](/molmil-images/mine/4nxe) | Crystal structure of iLOV-I486(2LT) at pH 6.5 | Descriptor: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | Authors: | Wang, J, Liu, X, Li, J. | Deposit date: | 2013-12-09 | Release date: | 2014-09-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers. J.Am.Chem.Soc., 136, 2014
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4NXF
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![BU of 4nxf by Molmil](/molmil-images/mine/4nxf) | Crystal structure of iLOV-I486(2LT) at pH 8.0 | Descriptor: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | Authors: | Wang, J, Liu, X, Li, J. | Deposit date: | 2013-12-09 | Release date: | 2014-09-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.766 Å) | Cite: | Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers. J.Am.Chem.Soc., 136, 2014
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4ELS
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![BU of 4els by Molmil](/molmil-images/mine/4els) | Structure of E. Coli. 1,4-dihydroxy-2- naphthoyl coenzyme A synthases (MENB) in complex with bicarbonate | Descriptor: | 1,2-ETHANEDIOL, 1,4-Dihydroxy-2-naphthoyl-CoA synthase, BICARBONATE ION, ... | Authors: | Sun, Y.R, Song, H.G, Li, J, Jiang, M, Li, Y, Zhou, J.H, Guo, Z.H. | Deposit date: | 2012-04-11 | Release date: | 2012-06-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways Biochemistry, 51, 2012
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4ELW
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![BU of 4elw by Molmil](/molmil-images/mine/4elw) | Structure of E. coli. 1,4-dihydroxy-2- naphthoyl coenzyme A synthases (MENB) in complex with nitrate | Descriptor: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, GLYCEROL, ... | Authors: | Sun, Y.R, Song, H.G, Li, J, Jiang, M, Li, Y, Zhou, J.H, Guo, Z.H. | Deposit date: | 2012-04-11 | Release date: | 2012-06-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.551 Å) | Cite: | Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways Biochemistry, 51, 2012
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