6Z4C
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![BU of 6z4c by Molmil](/molmil-images/mine/6z4c) | The structure of the N-terminal domain of RssB from E. coli | Descriptor: | Regulator of RpoS | Authors: | Zeth, K, Dimce, M, Terrence, D.M, Schuenemann, V, Dougan, D. | Deposit date: | 2020-05-25 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insight into the RssB-Mediated Recognition and Delivery of sigma s to the AAA+ Protease, ClpXP. Biomolecules, 10, 2020
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6NIY
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![BU of 6niy by Molmil](/molmil-images/mine/6niy) | A high-resolution cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex | Descriptor: | Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | dal Maso, E, Glukhova, A, Zhu, Y, Garcia-Nafria, J, Tate, C.G, Atanasio, S, Reynolds, C.A, Ramirez-Aportela, E, Carazo, J.-M, Hick, C.A, Furness, S.G.B, Hay, D.L, Liang, Y.-L, Miller, L.J, Christopoulos, A, Wang, M.-W, Wootten, D, Sexton, P.M. | Deposit date: | 2019-01-02 | Release date: | 2019-01-23 | Last modified: | 2020-04-08 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | The Molecular Control of Calcitonin Receptor Signaling. Acs Pharmacol Transl Sci, 2, 2019
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2H3X
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![BU of 2h3x by Molmil](/molmil-images/mine/2h3x) | Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes Faecalis (Form 3) | Descriptor: | Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION | Authors: | Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S. | Deposit date: | 2006-05-23 | Release date: | 2006-11-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis. Biochemistry, 45, 2006
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3HVI
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![BU of 3hvi by Molmil](/molmil-images/mine/3hvi) | Rat catechol O-methyltransferase in complex with a catechol-type, N6-ethyladenine-containing bisubstrate inhibitor | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, CHLORIDE ION, Catechol O-methyltransferase, ... | Authors: | Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G. | Deposit date: | 2009-06-16 | Release date: | 2009-10-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor. Angew.Chem.Int.Ed.Engl., 48, 2009
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6NB9
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![BU of 6nb9 by Molmil](/molmil-images/mine/6nb9) | Amyloid-Beta (20-34) with L-isoaspartate 23 | Descriptor: | Amyloid-beta A4 protein | Authors: | Sawaya, M.R, Warmack, R.A, Boyer, D.R, Zee, C.T, Richards, L.S, Cascio, D, Gonen, T, Clarke, S.G, Eisenberg, D.S. | Deposit date: | 2018-12-06 | Release date: | 2019-08-07 | Last modified: | 2022-09-07 | Method: | ELECTRON CRYSTALLOGRAPHY (1.05 Å) | Cite: | Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun, 10, 2019
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6Z6F
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![BU of 6z6f by Molmil](/molmil-images/mine/6z6f) | HDAC-PC | Descriptor: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | Authors: | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | Deposit date: | 2020-05-28 | Release date: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Sci Adv, 7, 2021
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6Z6H
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![BU of 6z6h by Molmil](/molmil-images/mine/6z6h) | HDAC-DC | Descriptor: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | Authors: | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | Deposit date: | 2020-05-28 | Release date: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (8.55 Å) | Cite: | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Sci Adv, 7, 2021
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6Z6O
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![BU of 6z6o by Molmil](/molmil-images/mine/6z6o) | HDAC-TC | Descriptor: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | Authors: | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | Deposit date: | 2020-05-28 | Release date: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Sci Adv, 7, 2021
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6TAM
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![BU of 6tam by Molmil](/molmil-images/mine/6tam) | |
6Z6P
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![BU of 6z6p by Molmil](/molmil-images/mine/6z6p) | HDAC-PC-Nuc | Descriptor: | DNA (145-MER), HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, ... | Authors: | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | Deposit date: | 2020-05-28 | Release date: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (4.43 Å) | Cite: | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Sci Adv, 7, 2021
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4ADY
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![BU of 4ady by Molmil](/molmil-images/mine/4ady) | Crystal structure of 26S proteasome subunit Rpn2 | Descriptor: | 26S PROTEASOME REGULATORY SUBUNIT RPN2 | Authors: | Kulkarni, K, He, J, Da Fonseca, P.C.A, Krutauz, D, Glickman, M.H, Barford, D, Morris, E.P. | Deposit date: | 2012-01-04 | Release date: | 2012-03-14 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Structure of the 26S Proteasome Subunit Rpn2 Reveals its Pc Repeat Domain as a Closed Toroid of Two Concentric Alpha-Helical Rings Structure, 20, 2012
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4AFU
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![BU of 4afu by Molmil](/molmil-images/mine/4afu) | Human Chymase - Fynomer Complex | Descriptor: | CHYMASE, FYNOMER | Authors: | Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M. | Deposit date: | 2012-01-23 | Release date: | 2012-07-11 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain. Mabs, 4, 2012
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6TIC
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![BU of 6tic by Molmil](/molmil-images/mine/6tic) | |
6TIN
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![BU of 6tin by Molmil](/molmil-images/mine/6tin) | |
2GTD
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![BU of 2gtd by Molmil](/molmil-images/mine/2gtd) | Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria | Descriptor: | Type III Pantothenate Kinase | Authors: | Yang, K, Eyobo, Y, Brand, A.L, Martynowski, D, Tomchick, D. | Deposit date: | 2006-04-27 | Release date: | 2006-08-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of a Type III Pantothenate Kinase: Insight into the Mechanism of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria. J.Bacteriol., 188, 2006
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4AP6
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![BU of 4ap6 by Molmil](/molmil-images/mine/4ap6) | Crystal structure of human POFUT2 E54A mutant in complex with GDP- fucose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ... | Authors: | Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H. | Deposit date: | 2012-03-30 | Release date: | 2012-08-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.401 Å) | Cite: | Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation. Embo J., 31, 2012
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6TGX
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![BU of 6tgx by Molmil](/molmil-images/mine/6tgx) | Crystal structure of Arabidopsis thaliana NAA60 in complex with a bisubstrate analogue | Descriptor: | Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA | Authors: | Layer, D, Kopp, J, Lapouge, K, Sinning, I. | Deposit date: | 2019-11-18 | Release date: | 2020-06-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response. New Phytol., 228, 2020
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2H47
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![BU of 2h47 by Molmil](/molmil-images/mine/2h47) | Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dephydrogenase and Azurin from Alcaligenes Faecalis (Form 1) | Descriptor: | Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION | Authors: | Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S. | Deposit date: | 2006-05-23 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis. Biochemistry, 45, 2006
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6Z5U
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3R22
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![BU of 3r22 by Molmil](/molmil-images/mine/3r22) | Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (Part I) | Descriptor: | N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide, Serine/threonine-protein kinase 6 | Authors: | Zhang, L, Fan, J, Chong, J.-H, Cesana, A, Tam, B, Gilson, C, Boykin, C, Wang, D, Marcotte, D, Le Brazidec, J.-Y, Aivazian, D, Piao, J, Lundgren, K, Hong, K, Vu, K, Nguyen, K. | Deposit date: | 2011-03-11 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I). Bioorg.Med.Chem.Lett., 21, 2011
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2KPJ
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![BU of 2kpj by Molmil](/molmil-images/mine/2kpj) | Solution Structure Of Protein SOS-response transcriptional repressor, LexA From Eubacterium rectale. Northeast Structural Genomics Consortium Target ErR9A | Descriptor: | SOS-response transcriptional repressor, LexA | Authors: | Wu, Y, Eletsky, A, Lee, D, Ghosh, A, Buchwald, W, Zhang, Q, Janjua, H, Garcia, E, Nair, R, Sukumaran, D, Rost, B, Acton, T, Xiao, R, Everett, J, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-10-16 | Release date: | 2009-11-17 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution Structure Of Protein SOS-response transcriptional repressor, LexA From Eubacterium rectale. Northeast Structural Genomics Consortium Target ErR9A To be Published
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4EE9
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![BU of 4ee9 by Molmil](/molmil-images/mine/4ee9) | Crystal structure of the RBcel1 endo-1,4-glucanase | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoglucanase | Authors: | Delsaute, M, Berlemont, R, Van Elder, D, Galleni, M, Bauvois, C. | Deposit date: | 2012-03-28 | Release date: | 2013-04-03 | Last modified: | 2013-08-14 | Method: | X-RAY DIFFRACTION (1.381 Å) | Cite: | Three-dimensional structure of RBcel1, a metagenome-derived psychrotolerant family GH5 endoglucanase. Acta Crystallogr.,Sect.F, 69, 2013
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4RV2
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![BU of 4rv2 by Molmil](/molmil-images/mine/4rv2) | Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium smegmatis | Descriptor: | MaoC family protein, SULFATE ION, UPF0336 protein MSMEG_1340/MSMEI_1302 | Authors: | Biswas, R, Hazra, D, Dutta, D, Das, A.K. | Deposit date: | 2014-11-24 | Release date: | 2015-02-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of dehydratase component HadAB complex of mycobacterial FAS-II pathway. Biochem.Biophys.Res.Commun., 458, 2015
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5E0Q
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3HVJ
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![BU of 3hvj by Molmil](/molmil-images/mine/3hvj) | Rat catechol O-methyltransferase in complex with a catechol-type, N6-propyladenine-containing bisubstrate inhibitor | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Catechol O-methyltransferase, ... | Authors: | Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G. | Deposit date: | 2009-06-16 | Release date: | 2009-10-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor. Angew.Chem.Int.Ed.Engl., 48, 2009
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